Annual Report 2022

Department of Endoscopy, Respiratory Endoscopy Division

Takaaki Tsuchida, Yuji Matsumoto, Tatsuya Imabayashi, Keigo Uchimura

Introduction

 More than 1,000 bronchoscopies were performed between April 2022 and March 2023 (Table 1). We are one of the facilities with the highest number of bronchoscopies performed in Japan. Almost all cases of peripheral and central pulmonary lesions are diagnosed on an outpatient basis, and sedation is used in combination with bronchoscopy to reduce patient discomfort.

 The special feature of our hospital is the use of endobronchial ultrasound (EBUS-TBNA, radial EBUS) for almost all examinations, and for small peripheral lesions, virtual bronchoscopy and virtual fluoroscopy using workstations and other instruments are employed to simulate the lesion before the examination. Efforts have been made to shorten the length of the procedure.

 Guided biopsies are combined with rapid onsite cytology. Cryobiopsies have been used to diagnose ground grass nodules or to obtain large specimens especially for next-generation sequencing.

 Stenting for airway stenosis and tumor ablation have also been performed. We actively performed thoracoscopy under local anesthesia for cases with unexplained pleural effusion and pleural thickening.

The Team and What We Do

 Endobronchial ultrasonography (EBUS) is used not only to evaluate mediastinal or hilar malignant lesions but also to evaluate whether the biopsy devices can be directed to the peripheral lung lesions. A total of 376 cases of EBUS-TBNA (EBUS-guided transbronchial needle aspiration) were performed as a less invasive procedure to improve the diagnosis of patients with mediastinal or hilar lymph node swelling. Transbronchial biopsies with virtual navigation were performed in most of the peripheral pulmonary lesions.

 Patients with endobronchial stenosis were treated with airway stent placement, debulking with a cryoprobe and/or endobronchial electrocautery ablation. Medical thoracoscopy under local anesthesia were performed in the endoscopic examination room on patients with unknown pleural effusion and/or pleural thickening.

Research Activities

1)  We conducted a trial of photodynamic therapy for peripheral small lung cancers.

2)  The usefulness of ROSE during cryo-biopsy in respiratory endoscopy was demonstrated.

3)  The usefulness of convex-type ultrasound bronchoscopy-guided forceps biopsy was demonstrated.

4)  The role of core tissue in next-generation sequencing analysis of ultrasound bronchoscopy-guided needle puncture aspiration biopsy specimens was demonstrated.

5)  We demonstrated the safety of day treatment of photodynamic therapy.

Clinical Trials

 The world's first multicenter trial of photodynamic therapy for peripheral lung cancer was performed.

Education

 Since the flexible bronchoscope was developed at our hospital for the first time in the world, many residents and doctors from overseas have wished to receive training at our hospital, and we actively accept them. This year, however, due to the spread of COVID-19, the number of overseas doctors was limited. On the other hand, we have given many residents opportunities to write papers and present at conferences.

Future Prospects

1) We will complete a multicenter trial of photodynamic therapy for small peripheral lung cancer.

2) We will conduct a randomized controlled trial to evaluate the efficacy of cryo-biopsy in the bronchoscopic diagnosis of peripheral lung lesions.

3) We will develop a method to nondestructively understand tissue architecture by X-ray phase imaging.

4) We will investigate the usefulness of regular-diameter forceps for ultrasound bronchoscopy-guided intranodal forceps biopsy.

5) We will develop a new diagnostic method for malignant tumors using a tabletop electron microscope.

6) We will develop diagnostic and therapeutic procedures that employ minimally invasive technique of bronchoscopy.

7) We will conduct a research on multidimensional information analysis of lung cancer pathology and examine the potential diagnostic ability of ultra-high-resolution CT images for lung cancer.

8) We will lead a prospective observational study using a multicenter database on respiratory endoscopy in Japan.

List of papers published in 2022

Journal

1. Matsuzaki J, Kato K, Oono K, Tsuchiya N, Sudo K, Shimomura A, Tamura K, Shiino S, Kinoshita T, Daiko H, Wada T, Katai H, Ochiai H, Kanemitsu Y, Takamaru H, Abe S, Saito Y, Boku N, Kondo S, Ueno H, Okusaka T, Shimada K, Ohe Y, Asakura K, Yoshida Y, Watanabe SI, Asano N, Kawai A, Ohno M, Narita Y, Ishikawa M, Kato T, Fujimoto H, Niida S, Sakamoto H, Takizawa S, Akiba T, Okanohara D, Shiraishi K, Kohno T, Takeshita F, Nakagama H, Ota N, Ochiya T. Prediction of tissue-of-origin of early stage cancers using serum miRNomes. JNCI cancer spectrum, 7:pkac080, 2023

2. Takemura C, Imabayashi T, Furuse H, Uchimura K, Matsumoto Y, Tsuchida T, Watanabe SI. Thoracic SMARCA4-deficient undifferentiated tumor diagnosed by transbronchial mediastinal cryobiopsy: A case report. Thoracic cancer, 14:953-957, 2023

3. Konno-Yamamoto A, Matsumoto Y, Imabayashi T, Tanaka M, Uchimura K, Nakagomi T, Yanase K, So C, Ohe Y, Tsuchida T. Feasibility of Modified Endobronchial Ultrasound-Guided Intranodal Forceps Biopsy: A Retrospective Analysis. Respiration; international review of thoracic diseases, 102:143-153, 2023

4. Furuse H, Matsumoto Y, Nakai T, Tanaka M, Nishimatsu K, Uchimura K, Imabayashi T, Tsuchida T, Ohe Y. Diagnostic efficacy of cryobiopsy for peripheral pulmonary lesions: A propensity score analysis. Lung cancer (Amsterdam, Netherlands), 178:220-228, 2023

5. Uchimura K, Imabayashi T, Matsumoto Y, Tsuchida T. Kimura’s Disease Diagnosed with Pleural Tumor. Internal medicine (Tokyo, Japan), 62:805-806, 2023

6. Suzuki H, Ono H, Hirasawa T, Takeuchi Y, Ishido K, Hoteya S, Yano T, Tanaka S, Toya Y, Nakagawa M, Toyonaga T, Takemura K, Hirasawa K, Matsuda M, Yamamoto H, Tsuji Y, Hashimoto S, Yuki M, Oyama T, Takenaka R, Yamamoto Y, Naito Y, Yamamoto K, Kobayashi N, Kawahara Y, Hirano M, Koizumi S, Hori S, Tajika M, Hikichi T, Yao K, Yokoi C, Ohnita K, Hisanaga Y, Sumiyoshi T, Kitamura S, Tanaka H, Shimoda R, Shimazu T, Takizawa K, Tanabe S, Kondo H, Iishi H, Ninomiya M, Oda I. Long-term Survival After Endoscopic Resection For Gastric Cancer: Real-world Evidence From a Multicenter Prospective Cohort. Clinical gastroenterology and hepatology, 21:307-318.e2, 2023

7. Fukushi G, Yamada M, Kakugawa Y, Gotoh M, Tanabe N, Ushiama M, Watanabe T, Yamazaki T, Matsumoto M, Hirata M, Nakajima T, Sugano K, Yoshida T, Matsuda T, Igarashi Y, Saito Y. Genotype-phenotype correlation of small-intestinal polyps on small-bowel capsule endoscopy in familial adenomatous polyposis. Gastrointestinal endoscopy, 97:59-68.e7, 2023

8. Hiki K, Ogata D, Hisada I, Sakamoto T, Hiroyuki T, Yamakawa K, Namikawa K, Takahashi A, Saito Y, Yamazaki N. Minimally invasive surgery combined with excision and endoscopic submucosal dissection for anorectal melanoma. The Journal of dermatology, 50:e26-e27, 2023

9. Hirata S, Toyoshima N, Takamaru H, Yamada M, Kobayashi N, Kozu T, Saito Y. Underwater endoscopic mucosal resection with submucosal injection. Endoscopy, 55:E70-E71, 2023

10. Takamaru H, Saito Y, Toyoshima N, Yamada M, Sakamoto T, Matsuda T. Polyglycolic acid sheet with clipping for closing delayed perforation after colonic endoscopic submucosal dissection. Endoscopy, 55:E211-E213, 2023

11. Uraoka T, Uedo N, Oyama T, Saito Y, Yahagi N, Fujimoto A, Kawahara Y, Mabe K, Hikichi T, Yamamoto Y, Tajiri H. Efficacy and Safety of a Novel Hemostatic Peptide Solution During Endoscopic Submucosal Dissection: A Multicenter Randomized Controlled Trial. The American journal of gastroenterology, 118:276-283, 2023

12. Saito Y. Pathologic sm2 carries a moderate risk of metastases even without other unfavorable factors, but positive horizontal margins have low local recurrence risk after en bloc resection. Endoscopy, 55:252-254, 2023

13. Kadota T, Ishihara R, Hatta W, Yoshida M, Kanzaki H, Kikuchi D, Ono Y, Abe S, Yamamoto Y, Yoshio T, Urabe Y, Yamaguchi N, Nagami Y, Iizuka T, Takahashi H, Oyama T, Yano T. Multi-institutional questionnaire on treatment strategies for superficial entire circumferential esophageal squamous cell carcinoma. DEN open, 3:e206, 2023

14. Tsuchida T, Matsumoto Y, Imabayashi T, Uchimura K. A study of laser dose in photodynamic therapy with talaporfin sodium for malignant central airway stenosis. Photodiagnosis and photodynamic therapy, 41:103315, 2023

15. Hirai Y, Abe S, Makiguchi ME, Sekiguchi M, Nonaka S, Suzuki H, Yoshinaga S, Saito Y. Endoscopic Resection of Undifferentiated Early Gastric Cancer. Journal of gastric cancer, 23:146-158, 2023

16. Tamura K, Uchimura K, Furuse H, Imabayashi T, Matsumoto Y, Tsuchida T. Mucoepidermoid carcinoma cured by a combination of high-frequency snare and photodynamic therapy: A case report. Thoracic cancer, 14:1306-1310, 2023

17. Imabayashi T, Matsumoto Y, Uchimura K, Furuse H, Tsuchida T. Computed Tomography Bronchus Sign Subclassification during Radial Endobronchial Ultrasound-Guided Transbronchial Biopsy: A Retrospective Analysis. Diagnostics (Basel, Switzerland), 13:1064, 2023

18. Yamada M, Shino R, Kondo H, Yamada S, Takamaru H, Sakamoto T, Bhandari P, Imaoka H, Kuchiba A, Shibata T, Saito Y, Hamamoto R. Robust automated prediction of the revised Vienna Classification in colonoscopy using deep learning: development and initial external validation. Journal of gastroenterology, 57:879-889, 2022

19. Ishiguro Y, Uchimura K, Furuse H, Imabayashi T, Matsumoto Y, Watanabe SI, Tsuchida T. Esophageal submucosal tumor diagnosed with EBUS-guided transbronchial mediastinal cryobiopsy: A case report. Thoracic cancer, 13:3068-3072, 2022

20. Kakeji Y, Ishikawa T, Suzuki S, Akazawa K, Irino T, Miyashiro I, Ono H, Suzuki H, Tanabe S, Kadowaki S, Muro K, Fukagawa T, Nunobe S, Wada T, Katai H, Kodera Y. A retrospective 5-year survival analysis of surgically resected gastric cancer cases from the Japanese Gastric Cancer Association nationwide registry (2001-2013). Gastric cancer, 25:1082-1093, 2022

21. Shiroma H, Shiba S, Erawijantari PP, Takamaru H, Yamada M, Sakamoto T, Kanemitsu Y, Mizutani S, Soga T, Saito Y, Shibata T, Fukuda S, Yachida S, Yamada T. Surgical Treatment for Colorectal Cancer Partially Restores Gut Microbiome and Metabolome Traits. mSystems, 7:e0001822, 2022

22. Kasuga K, Oda I, Nonaka S, Abe S, Suzuki H, Uraoka T, Saito Y. Endoscopic complete closure of duodenal mucosal defects using a clip with a looped thread after endoscopic resection. Endoscopy, 54:E135-E136, 2022

23. Kasuga K, Saito Y, Takamaru H, Yamada M, Sakamoto T, Sekine S, Uraoka T. Optical real-time biopsy by endocytoscopy: a case of sessile serrated lesion with dysplasia. Endoscopy, 54:E249-E251, 2022

24. Kasuga K, Abe S, Oda I, Yoshinaga S, Suzuki H, Uraoka T, Saito Y. Guidewire-assisted technique for gastroscope insertion through stricture of Zenker’s diverticulum for esophageal endoscopic submucosal dissection. Endoscopy, 54:E279-E280, 2022

25. Sakamoto T, Nakashima H, Nakamura K, Nagahama R, Saito Y. Performance of Computer-Aided Detection and Diagnosis of Colorectal Polyps Compares to That of Experienced Endoscopists. Digestive diseases and sciences, 67:3976-3983, 2022

26. Harai S, Hijioka S, Maruki Y, Ohba A, Nagashio Y, Okusaka T, Saito Y. Endoscopic ultrasound-guided hepaticoduodenostomy with anterograde stenting for recurrent hepatic hilar obstruction. Endoscopy, 54:E398-E400, 2022

27. Abe S, Makiguchi ME, Nonaka S, Suzuki H, Yoshinaga S, Saito Y. Emerging texture and color enhancement imaging in early gastric cancer. Digestive endoscopy, 34:714-720, 2022

28. Koyama Y, Fukuzawa M, Kono S, Madarame A, Morise T, Uchida K, Yamaguchi H, Sugimoto A, Nagata N, Kawai T, Takamaru H, Sekiguchi M, Yamada M, Sakamoto T, Matsuda T, Saito Y, Itoi T. Diagnostic efficacy of the Japan NBI Expert Team classification with dual-focus magnification for colorectal tumors. Surgical endoscopy, 36:5032-5040, 2022

29. Kobayashi N, Takeuchi Y, Ohata K, Igarashi M, Yamada M, Kodashima S, Hotta K, Harada K, Ikematsu H, Uraoka T, Sakamoto N, Doyama H, Abe T, Katagiri A, Hori S, Michida T, Yamaguchi T, Fukuzawa M, Kiriyama S, Fukase K, Murakami Y, Ishikawa H, Saito Y. Outcomes of endoscopic submucosal dissection for colorectal neoplasms: Prospective, multicenter, cohort trial. Digestive endoscopy, 34:1042-1051, 2022

30. Takamaru H, Saito Y, Hammoud GM, Mizuguchi Y, Cho H, Sekiguchi M, Yamada M, Sakamoto T, Matsuda T. Comparison of postpolypectomy bleeding events between cold snare polypectomy and hot snare polypectomy for small colorectal lesions: a large-scale propensity score-matched analysis. Gastrointestinal endoscopy, 95:982-989.e6, 2022

31. Uraoka T, Takizawa K, Tanaka S, Kashida H, Saito Y, Yahagi N, Yamano HO, Saito S, Hisabe T, Yao T, Watanabe M, Yoshida M, Saitoh Y, Tsuruta O, Igarashi M, Toyonaga T, Ajioka Y, Fujimoto K, Inoue H. Guidelines for Colorectal Cold Polypectomy (supplement to "Guidelines for Colorectal Endoscopic Submucosal Dissection/Endoscopic Mucosal Resection"). Digestive endoscopy, 34:668-675, 2022

32. Kitamura H, Hijioka S, Nagashio Y, Ban D, Esaki M, Okusaka T, Saito Y. A case of high grade pancreatic intraepithelial neoplasia diagnosed by endoscopic ultrasound-guided fine needle aspiration. Endoscopy, 54:E628-E630, 2022

33. Abe S, Tomizawa Y, Saito Y. Can artificial intelligence be your angel to diagnose early gastric cancer in real clinical practice? Gastrointestinal endoscopy, 95:679-681, 2022

34. Abe S, Hirai Y, Uozumi T, Makiguchi ME, Nonaka S, Suzuki H, Yoshinaga S, Oda I, Saito Y. Endoscopic resection of esophageal squamous cell carcinoma: Current indications and treatment outcomes. DEN open, 2:e45, 2022

35. Abe S, Yamazaki T, Hisada IT, Makiguchi ME, Yoshinaga S, Sato T, Nonaka S, Suzuki H, Oda I, Saito Y. Visibility of early gastric cancer in texture and color enhancement imaging. DEN open, 2:e46, 2022

36. Saito Y, Ono A, García VAJ, Mizuguchi Y, Hisada I, Takamaru H, Yamada M, Sekiguchi M, Makiguchi M, Sekine S, Abe S. Diagnosis and treatment of colorectal tumors: Differences between Japan and the West and future prospects. DEN open, 2:e66, 2022

37. Koga T, Hijioka S, Nagashio Y, Ohba A, Maruki Y, Yoshinari M, Hisada Y, Harai S, Kitamura H, Maehara K, Murashima Y, Kawasaki Y, Kawahara S, Takeshita K, Yamada N, Satake T, Kondo S, Morizane C, Ueno H, Okusaka T, Saito Y. Endoscopic ultrasound-guided choledochoduodenostomy without fistula dilation using a stent with a 5.9-Fr delivery system: Comparison to a conventional procedure with fistula dilation. DEN open, 2:e56, 2022

38. Ma X, Kawashima K, Saito Y. Using the string-clip method to retrieve the resected specimen allowed a clear observation of the colon and detection of a new lesion. Digestive endoscopy, 34:e77-e78, 2022

39. Abe S, Sekiguchi M. It is time to tailor endoscopic resection for early gastric cancer: Evaluate not only lesion but also patient. Digestive endoscopy, 34:826-827, 2022

40. Kawasaki Y, Hijioka S, Saito Y. Modified double-guidewire technique using a new double-lumen catheter and 0.018-inch guidewire for difficult biliary cannulation. Digestive endoscopy, 34:e71-e72, 2022

41. Saito Y, Yamada M, Mori Y. Although depth prediction of colorectal cancer with artificial intelligence is clinically relevant, standardization of histopathologic diagnosis should also be taken care of. Gastrointestinal endoscopy, 95:1195-1197, 2022

42. Takada K, Imabayashi T, Matsumoto Y, Uchimura K, Furuse H, Nishimatsu K, Tsuchida T. Feasibility of the modified balloon occlusion method using a 6-Fr balloon catheter in transbronchial lung cryobiopsy. Respiratory investigation, 60:425-429, 2022

43. Tsuchida T, Matsumoto Y, Imabayashi T, Uchimura K, Sasada S. Photodynamic therapy can be safely performed with Talaporfin sodium as a day treatment for central-type early-stage lung cancer. Photodiagnosis and photodynamic therapy, 38:102836, 2022

44. Lu D, Peng J, Wang Z, Sun Y, Zhai J, Wang Z, Chen Z, Matsumoto Y, Wang L, Xin SX, Cai K. Dielectric property measurements for the rapid differentiation of thoracic lymph nodes using XGBoost in patients with non-small cell lung cancer: a self-control clinical trial. Translational lung cancer research, 11:342-356, 2022

45. Toyoshima N, Abe S, Saito Y. In addition to free deep margins, R0 resection should be required for T1 colorectal cancers to inform further surgical resection. Endoscopy international open, 10:E291-E292, 2022

46. Yachida T, Matsuda T, Sakamoto T, Nakajima T, Kakugawa Y, Maeshima AM, Taniguchi H, Kushima R, Tobinai K, Kobara H, Masugata H, Masaki T, Saito Y. Endoscopic features of colorectal lymphoma according to histological type. JGH open, 6:257-262, 2022

47. Kawasaki Y, Hijioka S, Maehara K, Tamada K, Okusaka T, Saito Y. Endoscopic ultrasound-guided intra-afferent loop entero-enterostomy using a forward-viewing echoendoscope and insertion of a metal stent. Endoscopy, 54:E815-E817, 2022

48. Sakamoto T, Akiyama S, Narasaka T, Suzuki H, Sekine S, Saito Y, Tsuchiya K. Anal Intraepithelial Neoplasia: Precursor of Anal Squamous Cell Carcinoma. Journal of the anus, rectum and colon, 6:92-99, 2022

49. Ainechi D, Misawa M, Barua I, Larsen SLV, Paulsen V, Garborg KK, Aabakken L, Tønnesen CJ, Løberg M, Kalager M, Kudo SE, Hotta K, Ohtsuka K, Saito S, Ikematsu H, Saito Y, Matsuda T, Itoh H, Mori K, Bretthauer M, Mori Y. Impact of artificial intelligence on colorectal polyp detection for early-career endoscopists: an international comparative study. Scandinavian journal of gastroenterology, 57:1272-1277, 2022

50. Kuriki Y, Yoshioka T, Kamiya M, Komatsu T, Takamaru H, Fujita K, Iwaki H, Nanjo A, Akagi Y, Takeshita K, Hino H, Hino R, Kojima R, Ueno T, Hanaoka K, Abe S, Saito Y, Nakajima J, Urano Y. Development of a fluorescent probe library enabling efficient screening of tumour-imaging probes based on discovery of biomarker enzymatic activities. Chemical science, 13:4474-4481, 2022

51. Tanaka M, Matsumoto Y, Imabayashi T, Kawahara T, Tsuchida T. Diagnostic value of a new cryoprobe for peripheral pulmonary lesions: a prospective study. BMC pulmonary medicine, 22:226, 2022

52. Saito Y, Takamaru H, Toyoshima N. Resection depth: a very important advantage for underwater EMR. Endoscopy international open, 10:E729-E730, 2022

53. Ohata K, Kobayashi N, Sakai E, Takeuchi Y, Chino A, Takamaru H, Kodashima S, Hotta K, Harada K, Ikematsu H, Uraoka T, Murakami T, Tsuji S, Abe T, Katagiri A, Hori S, Michida T, Suzuki T, Fukuzawa M, Kiriyama S, Fukase K, Murakami Y, Ishikawa H, Saito Y. Long-term Outcomes After Endoscopic Submucosal Dissection for Large Colorectal Epithelial Neoplasms: A Prospective, Multicenter, Cohort Trial From Japan. Gastroenterology, 163:1423-1434.e2, 2022

54. Hoshino Y, Hanaoka K, Sakamoto K, Yasunaga M, Kojima T, Kotani D, Nomoto A, Sasaki E, Komatsu T, Ueno T, Takamaru H, Saito Y, Seto Y, Urano Y. Molecular design of near-infrared (NIR) fluorescent probes targeting exopeptidase and application for detection of dipeptidyl peptidase 4 (DPP-4) activity. RSC chemical biology, 3:859-867, 2022

55. Uchimura K, Furuse H, Imabayashi T, Matsumoto Y, Tsuchida T. Airway stenosis complicated by endobronchial ultrasound-guided tissue acquisition: A case report. Thoracic cancer, 13:2659-2663, 2022

56. Yamamoto Y, Yoshida N, Yano T, Horimatsu T, Uedo N, Kawata N, Kanzaki H, Hori S, Yao K, Abe S, Katada C, Yokoi C, Ohata K, Doyama H, Yoshimura K, Ishikawa H, Muto M. Assessment of Outcomes From 1-Year Surveillance After Detection of Early Gastric Cancer Among Patients at High Risk in Japan. JAMA network open, 5:e2227667, 2022

57. Muto Y, Uchimura K, Imabayashi T, Matsumoto Y, Furuse H, Tsuchida T. Clinical Utility of Rapid On-Site Evaluation of Touch Imprint Cytology during Cryobiopsy for Peripheral Pulmonary Lesions. Cancers, 14:4493, 2022

58. Odagiri H, Hatta W, Tsuji Y, Yoshio T, Yabuuchi Y, Kikuchi D, Tsuji S, Nagami Y, Hikichi T, Kobayashi M, Morita Y, Sumiyoshi T, Iguchi M, Tomida H, Inoue T, Mikami T, Hasatani K, Nishikawa J, Matsumura T, Nebiki H, Nakamatsu D, Ohnita K, Suzuki H, Ueyama H, Hayashi Y, Sugimoto M, Yamaguchi S, Michida T, Yada T, Asahina Y, Narasaka T, Kuribayashi S, Kiyotoki S, Mabe K, Fujishiro M, Masamune A, Hoteya S. Bleeding following Endoscopic Submucosal Dissection for Early Gastric Cancer in Surgically Altered Stomach. Digestion, 103:428-437, 2022

59. Messmann H, Bisschops R, Antonelli G, Libânio D, Sinonquel P, Abdelrahim M, Ahmad OF, Areia M, Bergman JJGHM, Bhandari P, Boskoski I, Dekker E, Domagk D, Ebigbo A, Eelbode T, Eliakim R, Häfner M, Haidry RJ, Jover R, Kaminski MF, Kuvaev R, Mori Y, Palazzo M, Repici A, Rondonotti E, Rutter MD, Saito Y, Sharma P, Spada C, Spadaccini M, Veitch A, Gralnek IM, Hassan C, Dinis-Ribeiro M. Expected value of artificial intelligence in gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement. Endoscopy, 54:1211-1231, 2022

60. Ito T, Matsumoto Y, Okachi S, Nishida K, Tanaka M, Imabayashi T, Tsuchida T, Hashimoto N. A Diagnostic Predictive Model of Bronchoscopy with Radial Endobronchial Ultrasound for Peripheral Pulmonary Lesions. Respiration; international review of thoracic diseases, 101:1148-1156, 2022

61. Morishita M, Uchimura K, Furuse H, Imabayashi T, Tsuchida T, Matsumoto Y. Predicting Malignant Lymph Nodes Using a Novel Scoring System Based on Multi-Endobronchial Ultrasound Features. Cancers, 14:5355, 2022

62. Kahaleh M, Bhagat V, Dellatore P, Tyberg A, Sarkar A, Shahid HM, Andalib I, Alkhiari R, Gaidhane M, Kedia P, Nieto J, Kumta NA, Dixon RE, Salameh H, Mavrogenis G, Bassioukas S, Abe S, Arentes VN, Morita FH, Sakai P, de Moura EG. Subepithelial tumors: How does endoscopic full-thickness resection & submucosal tunneling with endoscopic resection compare with laparoscopic endoscopic cooperative surgery? Endoscopy international open, 10:E1491-E1496, 2022