Annual Report 2018

Division of Boron Neutron Capture Therapy

Jun Itami, Hiroshi Igaki, Hiroaki Kurihara, Yoshitaka Narita, Seiichi Yoshimoto, Naoya Yamazaki, Mitsuko Masutani, Hiroyuki Okamoto, Akihisa Wakita, Satoshi Nakamura, Shie Nishioka, Yoshihisa Abe, Masashi Ito, Shouji Imamichi

Introduction

 Linear accelerator-based boron neutron therapy system was developed using a solid lithium target, which was realized for the first time in the world. Now physical and biological experiments are performed to measure the neutron spectrum from an accelerator. After the consultation with PMDA, the first-in-human trial will be launched next year.

The Team and What We Do

 Physical and biological experiments of neutron fields are performed.

Research activities

 The physical and biological experiments are intensively performed. Additionally, to select the optimal patients for BNCT, basic and clinical research of F-BPA PET/CT is being done.

Clinical trials

 First-in-human trials will be launched after consultation with PMDA in 2019.

Future prospects

 With the hospital based-BNCT system, recruitment of patients into BNCT clinical trials will be facilitated and the role of BNCT in oncology will be established very soon.