Annual Report 2022
Department of Infectious Diseases
Keiji Okinaka, Yusuke Ainoda
Introduction
The mission of the Department of Infectious Diseases is to provide consultation on clinical infectious diseases. We also work with the Office of Infection Control and Prevention to prevent healthcare-associated infections during cancer care.
The Team and What We Do
We provide medical support for fever and infections in patients with cancer (Table 1, a total of 270 cases during the period). Additionally, we collaborate with the Office of Infection Control and Prevention to contribute to infection control efforts.
- The total number of patients with positive blood cultures confirmed by our team was 318.
- The total number of patients confirmed to have treated by broad-spectrum antimicrobials by our team was 5,531 cases (including 411 cases out of 422 cases where consultation with the attending physician led to intervention within one week).
Table 1. Number of infectious diseases consultation
Research Activities
We have initiated research meetings and commenced supporting and promoting multidisciplinary research activities within the Office of Infection Control and Prevention.
Education
- We hold a weekly journal club with the participation of various professions in collaboration with the Office of Infection Control and Prevention of the National Cancer Center Hospital.
- We provided infectious diseases lectures to residents as one of the Clinical Oncology Education Intensive Course.
- We provided a presentation on cancer patient vaccinations at the multi-site cancer center joint conference.
- Monthly conferences are held in infectious disease departments across multiple facilities to provide resident education (Our team conducted a lecture in December).
Future Prospects
- We collaborate with the Office of Infection Control and Prevention to work on preventing the intra-hospital transmission of COVID-19.
- We promote vaccination as an infection prevention measure for cancer survivors.
- We have initiated the recruitment of residents and are actively engaged in nurturing the next generation.
- In partnership with the departments of infectious diseases of other national centers (National Center for Global Health and Medicine, National Center for Child Health and Development, and National Cancer Center Hospital), we will resume conferences from the fiscal year 2023.
List of papers published in 2022
Journal
1. Ainoda Y, Komaki-Yasuda K, Kano S, Hirai Y. False-positive fourth-generation HIV test result in a woman with Plasmodium malariae malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 117:147-148, 2023
2. Kimura SI, Kameda K, Harada K, Saburi M, Okinaka K, Shinohara A, Uchida N, Nishijima A, Ozawa Y, Tanaka M, Kuriyama T, Katayama Y, Sawa M, Ikegame K, Kawakita T, Kanda Y, Nakamae H, Ara T, Kimura T, Sato A, Fukuda T, Atsuta Y, Nakasone H. Risk and Predictive Factors for Candidemia After Allogeneic Hematopoietic Cell Transplantation: JSTCT Transplant Complications Working Group. Transplantation and cellular therapy, 28:209.e1-209.e9, 2022
3. Onishi A, Fuji S, Kitano S, Maeshima AM, Tajima K, Yamaguchi J, Kawashima I, Kawajiri A, Takemura T, Ito A, Tanaka T, Okinaka K, Inamoto Y, Kurosawa S, Kim SW, Munakata W, Maruyama D, Tobinai K, Fukuda T. Prognostic implication of CTLA-4, PD-1, and PD-L1 expression in aggressive adult T-cell leukemia-lymphoma. Annals of hematology, 101:799-810, 2022
4. Ainoda Y, Tanaka E, Wajima T, Nakaminami H, Hirota Y, Matsushita T, Hirai Y. A case of Shewanella algae-induced bacteremia in Japan: Case report and literature review. Journal of infection and chemotherapy, 28:1430-1432, 2022