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Home > Organization > Divisions and Independent Research Units > Division of Cancer Evolution > Research Papers > 2017

2017

  1. da Silva-Coelho, P., Kroeze, L. I., Yoshida K., Koorenhof-Scheele, T. N., Knops, R., van de Locht, L. T., de Graaf, A. O., Massop, M., Sandmann, S., Dugas, M., Stevens-Kroef, M. J., Cermak, J., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., de Witte, T., Blijlevens, N. M. A., Muus, P., Huls, G., van der Reijden, B. A., Ogawa, S., Jansen, J. H.: Clonal evolution in myelodysplastic syndromes. Nat Commun, 8: 15099 (2017).
  2. Hirabayashi, S., Seki, M., Hasegawa, D., Kato, M., Hyakuna, N., Shuo, T., Kimura, S., Yoshida K., Kataoka, K., Fujii, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Kiyokawa, N., Miyano, S., Ogawa, S., Takita, J., Manabe, A.: Constitutional abnormalities of IDH1 combined with secondary mutations predispose a patient with Maffucci syndrome to acute lymphoblastic leukemia. Pediatr Blood Cancer, 64:  (2017).
  3. Hiwatari, M., Seki, M., Akahoshi, S., Yoshida K., Miyano, S., Shiraishi, Y., Tanaka, H., Chiba, K., Ogawa, S., Takita, J.: Molecular studies reveal MLL-MLLT10/AF10 and ARID5B-MLL gene fusions displaced in a case of infantile acute lymphoblastic leukemia with complex karyotype. Oncol Lett, 14: 2295-2299 (2017).
  4. Hoshino, A., Okada, S., Yoshida K., Nishida, N., Okuno, Y., Ueno, H., Yamashita, M., Okano, T., Tsumura, M., Nishimura, S., Sakata, S., Kobayashi, M., Nakamura, H., Kamizono, J., Mitsui-Sekinaka, K., Ichimura, T., Ohga, S., Nakazawa, Y., Takagi, M., Imai, K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Ogawa, S., Kojima, S., Nonoyama, S., Morio, T., Kanegane, H.: Abnormal hematopoiesis and autoimmunity in human subjects with germline IKZF1 mutations. J Allergy Clin Immunol, 140: 223-231 (2017).
  5. Hosono, N., Makishima, H., Mahfouz, R., Przychodzen, B., Yoshida K., Jerez, A., LaFramboise, T., Polprasert, C., Clemente, M. J., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Sanada, M., Cui, E., Verma, A. K., McDevitt, M. A., List, A. F., Saunthararajah, Y., Sekeres, M. A., Boultwood, J., Ogawa, S., Maciejewski, J. P.: Recurrent genetic defects on chromosome 5q in myeloid neoplasms. Oncotarget, 8: 6483-6495 (2017).
  6. Ichimura, T., Yoshida K., Okuno, Y., Yujiri, T., Nagai, K., Nishi, M., Shiraishi, Y., Ueno, H., Toki, T., Chiba, K., Tanaka, H., Muramatsu, H., Hara, T., Kanno, H., Kojima, S., Miyano, S., Ito, E., Ogawa, S., Ohga, S.: Diagnostic challenge of Diamond-Blackfan anemia in mothers and children by whole-exome sequencing. Int J Hematol, 105: 515-520 (2017).
  7. Ikeda, F., Yoshida K., Toki, T., Uechi, T., Ishida, S., Nakajima, Y., Sasahara, Y., Okuno, Y., Kanezaki, R., Terui, K., Kamio, T., Kobayashi, A., Fujita, T., Sato-Otsubo, A., Shiraishi, Y., Tanaka, H., Chiba, K., Muramatsu, H., Kanno, H., Ohga, S., Ohara, A., Kojima, S., Kenmochi, N., Miyano, S., Ogawa, S., Ito, E.: Exome sequencing identified RPS15A as a novel causative gene for Diamond-Blackfan anemia. Haematologica, 102: e93-e96 (2017).
  8. Kato, I., Nishinaka, Y., Nakamura, M., Akarca, A. U., Niwa, A., Ozawa, H., Yoshida K., Mori, M., Wang, D., Morita, M., Ueno, H., Shiozawa, Y., Shiraishi, Y., Miyano, S., Gupta, R., Umeda, K., Watanabe, K., Koh, K., Adachi, S., Heike, T., Saito, M. K., Sanada, M., Ogawa, S., Marafioti, T., Watanabe, A., Nakahata, T., Enver, T.: Hypoxic adaptation of leukemic cells infiltrating the CNS affords a therapeutic strategy targeting VEGFA. Blood, 129: 3126-3129 (2017).
  9. Kato, M., Ishimaru, S., Seki, M., Yoshida K., Shiraishi, Y., Chiba, K., Kakiuchi, N., Sato, Y., Ueno, H., Tanaka, H., Inukai, T., Tomizawa, D., Hasegawa, D., Osumi, T., Arakawa, Y., Aoki, T., Okuya, M., Kaizu, K., Kato, K., Taneyama, Y., Goto, H., Taki, T., Takagi, M., Sanada, M., Koh, K., Takita, J., Miyano, S., Ogawa, S., Ohara, A., Tsuchida, M., Manabe, A.: Long-term outcome of 6-month maintenance chemotherapy for acute lymphoblastic leukemia in children. Leukemia, 31: 580-584 (2017).
  10. Makishima, H., Yoshizato, T., Yoshida K., Sekeres, M. A., Radivoyevitch, T., Suzuki, H., Przychodzen, B., Nagata, Y., Meggendorfer, M., Sanada, M., Okuno, Y., Hirsch, C., Kuzmanovic, T., Sato, Y., Sato-Otsubo, A., LaFramboise, T., Hosono, N., Shiraishi, Y., Chiba, K., Haferlach, C., Kern, W., Tanaka, H., Shiozawa, Y., Gomez-Segui, I., Husseinzadeh, H. D., Thota, S., Guinta, K. M., Dienes, B., Nakamaki, T., Miyawaki, S., Saunthararajah, Y., Chiba, S., Miyano, S., Shih, L. Y., Haferlach, T., Ogawa, S., Maciejewski, J. P.: Dynamics of clonal evolution in myelodysplastic syndromes. Nat Genet, 49: 204-212 (2017).
  11. Mandai, M., Watanabe, A., Kurimoto, Y., Hirami, Y., Morinaga, C., Daimon, T., Fujihara, M., Akimaru, H., Sakai, N., Shibata, Y., Terada, M., Nomiya, Y., Tanishima, S., Nakamura, M., Kamao, H., Sugita, S., Onishi, A., Ito, T., Fujita, K., Kawamata, S., Go, M. J., Shinohara, C., Hata, K. I., Sawada, M., Yamamoto, M., Ohta, S., Ohara, Y., Yoshida K., Kuwahara, J., Kitano, Y., Amano, N., Umekage, M., Kitaoka, F., Tanaka, A., Okada, C., Takasu, N., Ogawa, S., Yamanaka, S., Takahashi, M.: Autologous Induced Stem-Cell-Derived Retinal Cells for Macular Degeneration. N Engl J Med, 376: 1038-1046 (2017).
  12. Miyazaki, M., Miyazaki, K., Chen, K., Jin, Y., Turner, J., Moore, A. J., Saito, R., Yoshida K., Ogawa, S., Rodewald, H. R., Lin, Y. C., Kawamoto, H., Murre, C.: The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development. Immunity, 46: 818-834 e814 (2017).
  13. Monoi, A., Sugawa, M., Kato, M., Seki, M., Yoshida K., Shiraishi, Y., Sakaguchi, H., Ogawa, S., Takita, J.: Atypical dyskeratosis congenita diagnosed using whole-exome sequencing. Pediatr Int, 59: 933-935 (2017).
  14. Morita, K., Noura, M., Tokushige, C., Maeda, S., Kiyose, H., Kashiwazaki, G., Taniguchi, J., Bando, T., Yoshida K., Ozaki, T., Matsuo, H., Ogawa, S., Liu, P. P., Nakahata, T., Sugiyama, H., Adachi, S., Kamikubo, Y.: Autonomous feedback loop of RUNX1-p53-CBFB in acute myeloid leukemia cells. Sci Rep, 7: 16604 (2017).
  15. Muramatsu, H., Okuno, Y., Yoshida K., Shiraishi, Y., Doisaki, S., Narita, A., Sakaguchi, H., Kawashima, N., Wang, X., Xu, Y., Chiba, K., Tanaka, H., Hama, A., Sanada, M., Takahashi, Y., Kanno, H., Yamaguchi, H., Ohga, S., Manabe, A., Harigae, H., Kunishima, S., Ishii, E., Kobayashi, M., Koike, K., Watanabe, K., Ito, E., Takata, M., Yabe, M., Ogawa, S., Miyano, S., Kojima, S.: Clinical utility of next-generation sequencing for inherited bone marrow failure syndromes. Genet Med, 19: 796-802 (2017).
  16. Nguyen, T. B., Sakata-Yanagimoto, M., Asabe, Y., Matsubara, D., Kano, J., Yoshida K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Izutsu, K., Nakamura, N., Takeuchi, K., Miyoshi, H., Ohshima, K., Minowa, T., Ogawa, S., Noguchi, M., Chiba, S.: Identification of cell-type-specific mutations in nodal T-cell lymphomas. Blood Cancer J, 7: e516 (2017).
  17. Nishizawa, S., Sakata-Yanagimoto, M., Hattori, K., Muto, H., Nguyen, T., Izutsu, K., Yoshida K., Ogawa, S., Nakamura, N., Chiba, S.: BCL6 locus is hypermethylated in angioimmunoblastic T-cell lymphoma. Int J Hematol, 105: 465-469 (2017).
  18. Seki, M., Kimura, S., Isobe, T., Yoshida K., Ueno, H., Nakajima-Takagi, Y., Wang, C., Lin, L., Kon, A., Suzuki, H., Shiozawa, Y., Kataoka, K., Fujii, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Shimamura, T., Masuda, K., Kawamoto, H., Ohki, K., Kato, M., Arakawa, Y., Koh, K., Hanada, R., Moritake, H., Akiyama, M., Kobayashi, R., Deguchi, T., Hashii, Y., Imamura, T., Sato, A., Kiyokawa, N., Oka, A., Hayashi, Y., Takagi, M., Manabe, A., Ohara, A., Horibe, K., Sanada, M., Iwama, A., Mano, H., Miyano, S., Ogawa, S., Takita, J.: Recurrent SPI1 (PU.1) fusions in high-risk pediatric T cell acute lymphoblastic leukemia. Nat Genet, 49: 1274-1281 (2017).
  19. Sekinaka, Y., Mitsuiki, N., Imai, K., Yabe, M., Yabe, H., Mitsui-Sekinaka, K., Honma, K., Takagi, M., Arai, A., Yoshida K., Okuno, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Muramatsu, H., Kojima, S., Hira, A., Takata, M., Ohara, O., Ogawa, S., Morio, T., Nonoyama, S.: Common Variable Immunodeficiency Caused by FANC Mutations. J Clin Immunol, 37: 434-444 (2017).
  20. Shiozawa, Y., Malcovati, L., Galli, A., Pellagatti, A., Karimi, M., Sato-Otsubo, A., Sato, Y., Suzuki, H., Yoshizato, T., Yoshida K., Shiraishi, Y., Chiba, K., Makishima, H., Boultwood, J., Hellstrom-Lindberg, E., Miyano, S., Cazzola, M., Ogawa, S.: Gene expression and risk of leukemic transformation in myelodysplasia. Blood, 130: 2642-2653 (2017).
  21. Takagi, M., Ogata, S., Ueno, H., Yoshida K., Yeh, T., Hoshino, A., Piao, J., Yamashita, M., Nanya, M., Okano, T., Kajiwara, M., Kanegane, H., Muramatsu, H., Okuno, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Bando, Y., Kato, M., Hayashi, Y., Miyano, S., Imai, K., Ogawa, S., Kojima, S., Morio, T.: Haploinsufficiency of TNFAIP3 (A20) by germline mutation is involved in autoimmune lymphoproliferative syndrome. J Allergy Clin Immunol, 139: 1914-1922 (2017).
  22. Takagi, M., Yoshida, M., Nemoto, Y., Tamaichi, H., Tsuchida, R., Seki, M., Uryu, K., Nishii, R., Miyamoto, S., Saito, M., Hanada, R., Kaneko, H., Miyano, S., Kataoka, K., Yoshida K., Ohira, M., Hayashi, Y., Nakagawara, A., Ogawa, S., Mizutani, S., Takita, J.: Loss of DNA Damage Response in Neuroblastoma and Utility of a PARP Inhibitor. J Natl Cancer Inst, 109:  (2017).
  23. Togasaki, E., Takeda, J., Yoshida K., Shiozawa, Y., Takeuchi, M., Oshima, M., Saraya, A., Iwama, A., Yokote, K., Sakaida, E., Hirase, C., Takeshita, A., Imai, K., Okumura, H., Morishita, Y., Usui, N., Takahashi, N., Fujisawa, S., Shiraishi, Y., Chiba, K., Tanaka, H., Kiyoi, H., Ohnishi, K., Ohtake, S., Asou, N., Kobayashi, Y., Miyazaki, Y., Miyano, S., Ogawa, S., Matsumura, I., Nakaseko, C., Naoe, T.: Frequent somatic mutations in epigenetic regulators in newly diagnosed chronic myeloid leukemia. Blood Cancer J, 7: e559 (2017).
  24. Uryu, K., Nishimura, R., Kataoka, K., Sato, Y., Nakazawa, A., Suzuki, H., Yoshida K., Seki, M., Hiwatari, M., Isobe, T., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Koh, K., Hanada, R., Oka, A., Hayashi, Y., Ohira, M., Kamijo, T., Nagase, H., Takimoto, T., Tajiri, T., Nakagawara, A., Ogawa, S., Takita, J.: Identification of the genetic and clinical characteristics of neuroblastomas using genome-wide analysis. Oncotarget, 8: 107513-107529 (2017).
  25. Yamato, G., Shiba, N., Yoshida K., Shiraishi, Y., Hara, Y., Ohki, K., Okubo, J., Okuno, H., Chiba, K., Tanaka, H., Kinoshita, A., Moritake, H., Kiyokawa, N., Tomizawa, D., Park, M. J., Sotomatsu, M., Taga, T., Adachi, S., Tawa, A., Horibe, K., Arakawa, H., Miyano, S., Ogawa, S., Hayashi, Y.: ASXL2 mutations are frequently found in pediatric AML patients with t(8;21)/ RUNX1-RUNX1T1 and associated with a better prognosis. Genes Chromosomes Cancer, 56: 382-393 (2017).
  26. Yoshida, M., Hamanoue, S., Seki, M., Tanaka, M., Yoshida K., Goto, H., Ogawa, S., Takita, J., Tanaka, Y.: Metachronous anaplastic sarcoma of the kidney and thyroid follicular carcinoma as manifestations of DICER1 abnormalities. Hum Pathol, 61: 205-209 (2017).
  27. Yoshizato, T., Nannya, Y., Atsuta, Y., Shiozawa, Y., Iijima-Yamashita, Y., Yoshida K., Shiraishi, Y., Suzuki, H., Nagata, Y., Sato, Y., Kakiuchi, N., Matsuo, K., Onizuka, M., Kataoka, K., Chiba, K., Tanaka, H., Ueno, H., Nakagawa, M. M., Przychodzen, B., Haferlach, C., Kern, W., Aoki, K., Itonaga, H., Kanda, Y., Sekeres, M. A., Maciejewski, J. P., Haferlach, T., Miyazaki, Y., Horibe, K., Sanada, M., Miyano, S., Makishima, H., Ogawa, S.: Genetic abnormalities in myelodysplasia and secondary acute myeloid leukemia: impact on outcome of stem cell transplantation. Blood, 129: 2347-2358 (2017).
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