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Home > Organization > Divisions and Independent Research Units > Division of Cancer Evolution > Research Papers > 2020

2020

  1. Dingler, F. A., Wang, M., Mu, A., Millington, C. L., Oberbeck, N., Watcham, S., Pontel, L. B., Kamimae-Lanning, A. N., Langevin, F., Nadler, C., Cordell, R. L., Monks, P. S., Yu, R., Wilson, N. K., Hira, A., Yoshida K., Mori, M., Okamoto, Y., Okuno, Y., Muramatsu, H., Shiraishi, Y., Kobayashi, M., Moriguchi, T., Osumi, T., Kato, M., Miyano, S., Ito, E., Kojima, S., Yabe, H., Yabe, M., Matsuo, K., Ogawa, S., Gottgens, B., Hodskinson, M. R. G., Takata, M., Patel, K. J.: Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans. Mol Cell, 80: 996-1012 e1019 (2020).
  2. Inagaki-Kawata, Y., Yoshida K., Kawaguchi-Sakita, N., Kawashima, M., Nishimura, T., Senda, N., Shiozawa, Y., Takeuchi, Y., Inoue, Y., Sato-Otsubo, A., Fujii, Y., Nannya, Y., Suzuki, E., Takada, M., Tanaka, H., Shiraishi, Y., Chiba, K., Kataoka, Y., Torii, M., Yoshibayashi, H., Yamagami, K., Okamura, R., Moriguchi, Y., Kato, H., Tsuyuki, S., Yamauchi, A., Suwa, H., Inamoto, T., Miyano, S., Ogawa, S., Toi, M.: Genetic and clinical landscape of breast cancers with germline BRCA1/2 variants. Commun Biol, 3: 578 (2020).
  3. Kakiuchi, N., Yoshida K., Uchino, M., Kihara, T., Akaki, K., Inoue, Y., Kawada, K., Nagayama, S., Yokoyama, A., Yamamoto, S., Matsuura, M., Horimatsu, T., Hirano, T., Goto, N., Takeuchi, Y., Ochi, Y., Shiozawa, Y., Kogure, Y., Watatani, Y., Fujii, Y., Kim, S. K., Kon, A., Kataoka, K., Yoshizato, T., Nakagawa, M. M., Yoda, A., Nanya, Y., Makishima, H., Shiraishi, Y., Chiba, K., Tanaka, H., Sanada, M., Sugihara, E., Sato, T. A., Maruyama, T., Miyoshi, H., Taketo, M. M., Oishi, J., Inagaki, R., Ueda, Y., Okamoto, S., Okajima, H., Sakai, Y., Sakurai, T., Haga, H., Hirota, S., Ikeuchi, H., Nakase, H., Marusawa, H., Chiba, T., Takeuchi, O., Miyano, S., Seno, H., Ogawa, S.: Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis. Nature, 577: 260-265 (2020).
  4. Kanamori, T., Sanada, M., Ri, M., Ueno, H., Nishijima, D., Yasuda, T., Tachita, T., Narita, T., Kusumoto, S., Inagaki, A., Ishihara, R., Murakami, Y., Kobayashi, N., Shiozawa, Y., Yoshida K., Nakagawa, M. M., Nannya, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Horibe, K., Handa, H., Ogawa, S., Iida, S.: Genomic analysis of multiple myeloma using targeted capture sequencing in the Japanese cohort. Br J Haematol, 191: 755-763 (2020).
  5. Kimura, S., Seki, M., Kawai, T., Goto, H., Yoshida K., Isobe, T., Sekiguchi, M., Watanabe, K., Kubota, Y., Nannya, Y., Ueno, H., Shiozawa, Y., Suzuki, H., Shiraishi, Y., Ohki, K., Kato, M., Koh, K., Kobayashi, R., Deguchi, T., Hashii, Y., Imamura, T., Sato, A., Kiyokawa, N., Manabe, A., Sanada, M., Mansour, M. R., Ohara, A., Horibe, K., Kobayashi, M., Oka, A., Hayashi, Y., Miyano, S., Hata, K., Ogawa, S., Takita, J.: DNA methylation-based classification reveals difference between pediatric T-cell acute lymphoblastic leukemia and normal thymocytes. Leukemia, 34: 1163-1168 (2020).
  6. Kubota, Y., Seki, M., Kawai, T., Isobe, T., Yoshida, M., Sekiguchi, M., Kimura, S., Watanabe, K., Sato-Otsubo, A., Yoshida K., Suzuki, H., Kataoka, K., Fujii, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Hiwatari, M., Oka, A., Hayashi, Y., Miyano, S., Ogawa, S., Hata, K., Tanaka, Y., Takita, J.: Comprehensive genetic analysis of pediatric germ cell tumors identifies potential drug targets. Commun Biol, 3: 544 (2020).
  7. Matsuo, H., Yoshida K., Nakatani, K., Harata, Y., Higashitani, M., Ito, Y., Kamikubo, Y., Shiozawa, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Okada, A., Nannya, Y., Takeda, J., Ueno, H., Kiyokawa, N., Tomizawa, D., Taga, T., Tawa, A., Miyano, S., Meggendorfer, M., Haferlach, C., Ogawa, S., Adachi, S.: Fusion partner-specific mutation profiles and KRAS mutations as adverse prognostic factors in MLL-rearranged AML. Blood Adv, 4: 4623-4631 (2020).
  8. Mylonas, E., Yoshida K., Frick, M., Hoyer, K., Christen, F., Kaeda, J., Obenaus, M., Noerenberg, D., Hennch, C., Chan, W., Ochi, Y., Shiraishi, Y., Shiozawa, Y., Zenz, T., Oakes, C. C., Sawitzki, B., Schwarz, M., Bullinger, L., le Coutre, P., Rose-Zerilli, M. J. J., Ogawa, S., Damm, F.: Single-cell analysis based dissection of clonality in myelofibrosis. Nat Commun, 11: 73 (2020).
  9. Ochi, Y., Kon, A., Sakata, T., Nakagawa, M. M., Nakazawa, N., Kakuta, M., Kataoka, K., Koseki, H., Nakayama, M., Morishita, D., Tsuruyama, T., Saiki, R., Yoda, A., Okuda, R., Yoshizato, T., Yoshida K., Shiozawa, Y., Nannya, Y., Kotani, S., Kogure, Y., Kakiuchi, N., Nishimura, T., Makishima, H., Malcovati, L., Yokoyama, A., Takeuchi, K., Sugihara, E., Sato, T. A., Sanada, M., Takaori-Kondo, A., Cazzola, M., Kengaku, M., Miyano, S., Shirahige, K., Suzuki, H. I., Ogawa, S.: Combined Cohesin-RUNX1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes. Cancer Discov, 10: 836-853 (2020).
  10. Ogura, H., Ohga, S., Aoki, T., Utsugisawa, T., Takahashi, H., Iwai, A., Watanabe, K., Okuno, Y., Yoshida K., Ogawa, S., Miyano, S., Kojima, S., Yamamoto, T., Yamamoto-Shimojima, K., Kanno, H.: Novel COL4A1 mutations identified in infants with congenital hemolytic anemia in association with brain malformations. Hum Genome Var, 7: 42 (2020).
  11. Polprasert, C., Takeda, J., Niparuck, P., Rattanathammethee, T., Pirunsarn, A., Suksusut, A., Kobbuaklee, S., Wudhikarn, K., Lawasut, P., Kongkiatkamon, S., Chuncharunee, S., Songserm, K., Phowthongkum, P., Bunworasate, U., Nannya, Y., Yoshida K., Makishima, H., Ogawa, S., Rojnuckarin, P.: Novel DDX41 variants in Thai patients with myeloid neoplasms. Int J Hematol, 111: 241-246 (2020).
  12. Sekiguchi, M., Seki, M., Kawai, T., Yoshida K., Yoshida, M., Isobe, T., Hoshino, N., Shirai, R., Tanaka, M., Souzaki, R., Watanabe, K., Arakawa, Y., Nannya, Y., Suzuki, H., Fujii, Y., Kataoka, K., Shiraishi, Y., Chiba, K., Tanaka, H., Shimamura, T., Sato, Y., Sato-Otsubo, A., Kimura, S., Kubota, Y., Hiwatari, M., Koh, K., Hayashi, Y., Kanamori, Y., Kasahara, M., Kohashi, K., Kato, M., Yoshioka, T., Matsumoto, K., Oka, A., Taguchi, T., Sanada, M., Tanaka, Y., Miyano, S., Hata, K., Ogawa, S., Takita, J.: Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets. NPJ Precis Oncol, 4: 20 (2020).
  13. Ueno, H., Yoshida K., Shiozawa, Y., Nannya, Y., Iijima-Yamashita, Y., Kiyokawa, N., Shiraishi, Y., Chiba, K., Tanaka, H., Isobe, T., Seki, M., Kimura, S., Makishima, H., Nakagawa, M. M., Kakiuchi, N., Kataoka, K., Yoshizato, T., Nishijima, D., Deguchi, T., Ohki, K., Sato, A., Takahashi, H., Hashii, Y., Tokimasa, S., Hara, J., Kosaka, Y., Kato, K., Inukai, T., Takita, J., Imamura, T., Miyano, S., Manabe, A., Horibe, K., Ogawa, S., Sanada, M.: Landscape of driver mutations and their clinical impacts in pediatric B-cell precursor acute lymphoblastic leukemia. Blood Adv, 4: 5165-5173 (2020).
  14. Yasuda, T., Sanada, M., Nishijima, D., Kanamori, T., Iijima, Y., Hattori, H., Saito, A., Miyoshi, H., Ishikawa, Y., Asou, N., Usuki, K., Hirabayashi, S., Kato, M., Ri, M., Handa, H., Ishida, T., Shibayama, H., Abe, M., Iriyama, C., Karube, K., Nishikori, M., Ohshima, K., Kataoka, K., Yoshida K., Shiraishi, Y., Goto, H., Adachi, S., Kobayashi, R., Kiyoi, H., Miyazaki, Y., Ogawa, S., Kurahashi, H., Yokoyama, H., Manabe, A., Iida, S., Tomita, A., Horibe, K.: Clinical utility of target capture-based panel sequencing in hematological malignancies: A multicenter feasibility study. Cancer Sci, 111: 3367-3378 (2020).
  15. Yoshida K., Gowers, K. H. C., Lee-Six, H., Chandrasekharan, D. P., Coorens, T., Maughan, E. F., Beal, K., Menzies, A., Millar, F. R., Anderson, E., Clarke, S. E., Pennycuick, A., Thakrar, R. M., Butler, C. R., Kakiuchi, N., Hirano, T., Hynds, R. E., Stratton, M. R., Martincorena, I., Janes, S. M., Campbell, P. J.: Tobacco smoking and somatic mutations in human bronchial epithelium. Nature, 578: 266-272 (2020).
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