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Publications

2024

          1. Shinya Hasegawa, Yutaka Shoji, Mamoru Kato, Asmaa Elzawahry, Momoko Nagai, Min Gi, Shugo Suzuki, Hideki Wanibuchi, Sachiyo Mimaki, Katsuya Tsuchihara, Yukari Totsuka.
            Whole Genome Sequencing Analysis of Model Organisms Elucidates the Association Between Environmental Factors and Human Cancer Development.
            International Journal of Molecular Sciences, 2024, Volume 25, Issue 20.

          2. Takahiro Nishino, Mio Yumura, Kuniko Sunami, Takashi Kubo, Hitoshi Ichikawa, Tomoyo Yasuda, Eisaku Furukawa, Momoko Nagai, Yasushi Yatabe, Mamoru Kato, Takashi Kohno.
            Leveraging non-coding regions to guarantee the accuracy of small-sized panel-based tumor mutational burden estimates.
            Cancer Science, 2024
          3. Takashi Kubo, Kuniko Sunami, Takafumi Koyama, Mayuko Kitami, Yasuhiro Fujiwara, Shunsuke Kondo, Kan Yonemori, Emi Noguchi, Chigusa Morizane, Yasushi Goto, Aiko Maejima, Satoru Iwasa, Tetsuya Hamaguchi, Akira Kawai, Kenjiro Namikawa, Ayumu Arakawa, Masanaka Sugiyama, Makoto Ohno, Teruhiko Yoshida, Nobuyoshi Hiraoka, Akihiko Yoshida, Masayuki Yoshida, Takahiro Nishino, Eiji Furukawa, Daichi Narushima, Momoko Nagai, Mamoru Kato, Hiroshi Ichikawa, Yasuhiro Fujiwara, Takashi Kohno, Noboru Yamamoto.
            The impact of rare cancer and early-line treatments on the benefit of comprehensive genome profiling-based precision oncology.
            ESMO Open,2024 Apr 12;9(4):102981
 
Review Articles（総説）
          1.     Mamoru Kato
                Informatics on target sequencing
                Cancer Genopedia (Gan Genome Pedia, in Japanese), 2024, 137-138
                加藤　護
                ターゲットシークエンス情報解析
                がんゲノムペディア、2024, 137-138
          2.     Eisaku Furukawa, Mamoru Kato
                Variant annotation
                Cancer Genopedia (Gan Genome Pedia, in Japanese), 2024, 164-165
                古川　英作、加藤　護
                変異アノテーション
                がんゲノムペディア、2024, 164-165

2023

          1. Bunpei Miyazaki, Toshihide Ueno, Masanaka Sugiyama, Shinya Kojima, Ayumu Arakawa, Kayoko Tao, Kazuki Tanimura, Kouya Shiraishi, Shigehiro Yagishita, Shinji Kohsaka, Mamoru Kato, Nobutaka Kiyokawa, Yasushi Goto, Yasushi Yatabe, Akinobu Hamada, Hiroyuki Mano, Chitose Ogawa & Yosuke Tanaka
            Promoter swapping of truncated PDGFRB drives Ph-like acute lymphoblastic leukemia.
            npj Precision Oncology, 2023, 7, 132
          2. Kana Shimomura, Naoko Hattori, Naoko Iida, Yukari Muranaka, Kotomi Sato, Yuichi Shiraishi, Yasuhito Arai, Natsuko Hama, Tatsuhiro Shibata, Daichi Narushima, Mamoru Kato, Hiroyuki Takamaru, Koji Okamoto, Haruna Takeda
            Sleeping Beauty transposon mutagenesis identified genes and pathways involved in inflammation-associated colon tumor development.
            Nature communications, 2023, 14, 6514.1-16
          3. Mihoko Saito-Adachi, Natsuko Hama, Yasushi Totoki, Hiromi Nakamura, Yasuhito Arai, Fumie Hosoda, Hirofumi Rokutan, Shinichi Yachida, Mamoru Kato, Akihiko Fukagawa, Tatsuhiro Shibata
            Oncogenic structural aberration landscape in gastric cancer genomes
            Nature Communications, 2023, 14(3688)
          4. Yasushi Totoki, Mihoko Saito-Adachi, Yuichi Shiraishi, Daisuke Komura, Hiromi Nakamura, Akihiro Suzuki, Kenji Tatsuno, Hirofumi Rokutan, Natsuko Hama, Shogo Yamamoto, Hanako Ono, Yasuhito Arai, Fumie Hosoda, Hiroto Katoh, Kenichi Chiba, Naoko Iida, Genta Nagae, Hiroki Ueda, Chen Shihang, Shigeki Sekine, Hiroyuki Abe, Sachiyo Nomura, Tetsuya Matsuura, Eiji Sakai, Takashi Ohshima, Yasushi Rino, Khay Guan Yeoh, Jimmy So, Kaushal Sanghvi, Richie Soong, Akihiko Fukagawa, Shinichi Yachida, Mamoru Kato, Yasuyuki Seto, Tetsuo Ushiku, Atsushi Nakajima, Hitoshi Katai, Patrick Tan, Shumpei Ishikawa, Hiroyuki Aburatani, Tatsuhiro Shibata
            Multiancestry genomic and transcriptomic analysis of gastric cancer
            Nature Genetics, 2023, 55(4):581-594. doi: 10.1038/s41588-023-01333-x

    2022

            1. Motoo Nagane, Koichi Ichimura, Ritsuko Onuki, Daichi Narushima, Mai Honda Kitahara, Kaishi Satomi, Arata Tomiyama, Yasuhito Arai, Tatsuhiro Shibata, Yoshitaka Narita, Takeo Uzuka, Hideo Nakamura, Mitsutoshi Nakada, Yoshiki Arakawa, Takanori Ohnishi, Akitake Mukasa, Shota Tanaka, Toshihiko Wakabayashi, Tomokazu Aoki, Shigeki Aoki, Soichiro Shibui, Masao Matsutani, Keisuke Ishizawa, Hideaki Yokoo, Hiroyoshi Suzuki, Satoshi Morita, Mamoru Kato, Ryo Nishikawa
              Bevacizumab Beyond Progression for Newly Diagnosed Glioblastoma (BIOMARK): Phase II Safety, Efficacy and Biomarker Study
              Cancers, 2022, 14(22):5522. doi: 10.3390/cancers14225522
            2. Takashi Kohno, Mamoru Kato, Shinji Kohsaka, Tomohisa Sudo, Ikuo Tamai, Yuichi Shiraishi, Yusuke Okuma, Daisuke Ogasawara, Tatsuya Suzuki, Teruhiko Yoshida, Hiroyuki ManoC-CAT: The National Datacenter for Cancer Genomic Medicine in JapanCancer Discov, 2022, 12, 2509-2515
            3. Hironori Satoh, Yasuhito Arai, Eisaku Furukawa, Takashi Moriguchi, Natuko Hama, Tomoko Urushidate, Yasushi Totoki, Mamoru Kato, Yuichiro Ohe, Masayuki Yamamoto, Tatsuhiro Shibata
              Genomic landscape of chemical-induced lung tumors under Nrf2 different expression levels
              Carcinogenesis, 2022, 43(7):613-623. doi: 10.1093/carcin/bgac041
            4. Yusuke Suenaga+, Mamoru Kato+, Momoko Nagai, Kazuma Nakatani, Hiroyuki Kogashi, Miho Kobatake, Takashi Makino
              Open reading frame dominance indicates protein-coding potential of RNAs
              EMBO Rep, 2022, 23(6):e54321. doi: 10.15252/embr.202154321
            5. Hirokazu Takami, Asmaa Elzawahry, Yasin Mamatjan, Shintaro Fukushima, Kohei Fukuoka, Tomonari Suzuki, Takaaki Yanagisawa, Yuko Matsushita, Taishi Nakamura, Kaishi Satomi, Shota Tanaka, Akitake Mukasa, Nobuhito Saito, Masayuki Kanamori, Toshihiro Kumabe, Teiji Tominaga, Keiichi Kobayashi, Motoo Nagane, Toshihiko Iuchi, Kaoru Tamura, Taketoshi Maehara, Kazuhiko Sugiyama, Koji Yoshimoto, Keiichi Sakai, Masahiro Nonaka, Akio Asai, Kiyotaka Yokogami, Hideo Takeshima, Yoshitaka Narita, Soichiro Shibui, Yoichi Nakazato, Natsuko Hama, Yasushi Totoki, Mamoru Kato, Tatsuhiro Shibata, Ryo Nishikawa, Masao Matsutani, Koichi Ichimura, Intracranial Germ Cell Tumor Genome Analysis Consortium (the iGCT Consortium)
              Transcriptome and Methylome Analysis of CNS Germ Cell Tumor Finds its Cell-of-Origin in Embryogenesis and Reveals Shared Similarities with Testicular Counterparts
              Neuro Oncol, 2022, 24(8):1246-1258. doi: 10.1093/neuonc/noac021.
            6. Kotoe Oshima, Ken Kato, Yoshinori Ito, Hiroyuki Daiko, Isao Nozaki, Satoru Nakagawa, Yuichi Shibuya, Takashi Kojima, Yasushi Toh, Morihito Okada, Shuichi Hironaka, Yuji Akiyama, Yoshito Komatsu, Kazuhiro Maejima, Hidewaki Nakagawa, Ritsuko Onuki, Momoko Nagai, Mamoru Kato, Keisuke Kanato, Aya Kuchiba, Kenichi Nakamura, Yuko Kitagawa
              Prognostic biomarker study in patients with clinical stage I esophageal squamous cell carcinoma: JCOG0502-A1Cancer Science, 2022, 113, 1018–1027
     Review Articles（総説）
            1.     Mamoru Kato
                  Variant analysis in cancer genome medicine
                  Pathology and Clinical Medicine (Byouri-to Rinsyou, in Japanese), 2022, 40, 70-76
                  加藤　護
                  がんゲノム医療における変異解析
                  病理と臨床、2022, 40, 70-76

    2021

            1. Shinichi Yachida, Yasushi Totoki, Michael Noe, Yoichiro Nakatani, Masafumi Horie, Kenta Kawasaki, Hiromi Nakamura, Mihoko Saito-Adachi, Masami Suzuki, Erina Takai, Natsuko Hama, Ryota Higuchi, Seiko Hirono, Satoshi Shiba, Mamoru Kato, Eisaku Furukawa, Yasuhito Arai, Hirofumi Rokutan, Taiki Hashimoto, Shuichi Mitsunaga, Mitsuro Kanda, Hidenori Tanaka, So Takata, Ayaka Shimomura, Minoru Oshima, Wenzel M Hackeng, Tomoyuki Okumura, Keiichi Okano, Masakazu Yamamoto, Hiroki Yamaue, Chigusa Morizane, Koji Arihiro, Toru Furukawa, Toshiro Sato, Tohru Kiyono, Lodewijk A.A. Brosens, Laura D. Wood, Ralph H Hruban and Tatsuhiro Shibata
              Comprehensive Genomic Profiling of Neuroendocrine Carcinomas of the Gastrointestinal System
              Cancer Discov, 2021, 4, 1398–1405
            2. Hanako Ono, Yasuhito Arai, Eisaku Furukawa, Daichi Narushima, Tetsuya Matsuura, Hiromi Nakamura, Daisuke Shiokawa, Momoko Nagai, Toshio Imai, Koshi Mimori, Koji Okamoto, Yoshitaka Hippo, Tatsuhiro Shibata, Mamoru Kato
              Single-cell DNA and RNA sequencing reveals the dynamics of intra-tumor heterogeneity in a colorectal cancer model.
              BMC Biology, 2021, 19, 207.1-17
            3. Shinichi Mizuno, Rui Yamaguchi, Takanori Hasegawa, Shuto Hayashi, Masashi Fujita, Fan Zhang, Youngil Koh, Su-Yeon Lee, Sung-Soo Yoon,  Eigo Shimizu, Mitsuhiro Komura, Akihiro Fujimoto, Momoko Nagai, Mamoru Kato, Han Liang, Satoru Miyano, Zemin Zhang, Hidewaki Nakagawa, Seiya Imoto
              Immunogenomic Pan-cancer Landscape Reveals Immune Escape Mechanisms and Immunoediting Histories
              Scientific Reports, 2021, 15713.1-13
            4. Iurii S. Nagornov, Jo Nishino, Mamoru Kato
              Dataset of tugHall simulations of cell evolution for colorectal cancer
              Data in Brief, 2021, 34, 106719

    2020

            1. Iurii S. Nagornov, Jo Nishino, Mamoru Kato
              tugHall: A Tool to Reproduce Darwinian Evolution of Cancer Cells for Simulation-Based Personalized Medicine
              ISMCO 2020: Mathematical and Computational Oncology
              Lecture Notes in Computer Science, vol 12508, 71-76

            2. Daisuke Shiokawa, Hiroaki Sakai, Hirokazu Ohata, Toshiaki Miyazaki, Yusuke Kanda, Shigeki Sekine, Daichi Narushima, Masahito Hosokawa, Mamoru Kato, Yutaka Suzuki, Haruko Takeyama, Hideki Kambara, Hitoshi Nakagama and Koji Okamoto
              Slow-cycling cancer stem cells regulate progression and chemoresistance in colon cancer
              Cancer Res, 2020, 80, 4451-4464

            3. Yukari Totsuka, Yuya Maesako, Hanako Ono, Momoko Nagai, Mamoru Kato, Min Gi, Hideki Wanibuchi, Shoji Fukushima, Kazuhiro Shiizaki, Hitoshi Nakagama
              Comprehensive analysis of DNA adducts (DNA adductome analysis) in the liver of rats treated with 1,4-dioxane
              Proc. Jpn. Acad., Ser. B, 2020, 96, 180-187

            4. Iurii S. Nagornov and Mamoru Kato
              tugHall: a simulator of cancer-cell evolution based on the hallmarks of cancer and tumor-related genes
              Bioinformatics, 2020, 36, 3597–3599

            5. The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium
              Pan-cancer analysis of whole genomes
              Nature, 2020, 578, 82–93

            6. Erina Takai, Daichi Maeda, Zhuo Li, Yukitsugu Kudo-Asabe, Yasushi Totoki, Hiromi Nakamura, Akiko Nakamura, Rumi Nakamura, Misato Kirikawa, Yukinobu Ito, Makoto Yoshida, Takamitsu Inoue, Tomonori Habuchi, Shohei Ikoma, Hiroto Katoh, Mamoru Kato, Tatsuhiro Shibata, Shumpei Ishikawa, Shinichi Yachida, Akiteru Goto
              Post-mortem Plasma Cell-Free DNA Sequencing: Proof-of-Concept Study for the "Liquid Autopsy"
              Scientific Reports, 2020, 10, 2120.1-10

            7. Wei Jiao, Gurnit Atwal, Paz Polak, Rosa Karlic, Edwin Cuppen, PCAWG Tumor Subtypes and Clinical Translation Working Group (incl. Mamoru Kato), Alexandra Danyi, Jeroen de Ridder, Carla van Herpen, Martijn P. Lolkema, Neeltje Steeghs, Gad Getz, Quaid Morris, Lincoln D. Stein, PCAWG Consortium
              A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns.
              Nature communications, 2020, 11, 728.1-12
     Review Articles（総説）
            1.     Mamoru Kato
                  NCC Oncopanel and multigene panels abroad
                  Journal of Clinical and Experimental Medicine (Igaku-no Ayumi, in Japanese), 2020, 275, 419-423
                  加藤　護
                  NCCオンコパネルと海外の遺伝子パネル
                  医学のあゆみ、2020, 275, 419-423

    2019

            1. Kuniko Sunami, Hitoshi Ichikawa, Takashi Kubo, Mamoru Kato, Yutaka Fujiwara, Akihiko Shimomura, Takafumi Koyama, Hiroki Kakishima, Mayuko Kitami, Hiromichi Matsushita, Eisaku Furukawa, Daichi Narushima, Momoko Nagai, Hirokazu Taniguchi, Noriko Motoi, Shigeaki Sekine, Akiko Maeshima, Taisuke Mori, Reiko Watanabe, Masayuki Yoshida, Akihiko Yoshida, Hiroshi Yoshida, Kaishi Satomi, Aoi Sukeda, Taiki Hashimoto, Toshio Shimizu, Satoru Iwasa, Kan Yonemori, Ken Kato, Chigusa Morizane, Chitose Ogawa, Noriko Tanabe, Kokichi Sugano, Nobuyoshi Hiraoka, Kenji Tamura, Teruhiko Yoshida, Yasuhiro Fujiwara, Atsushi Ochiai, Noboru Yamamoto, Takashi Kohno
              Feasibility and utility of a panel testing for 114 cancer-associated genes in a clinical setting: A hospital-based study
              Cancer Science, 2019, 110, 1480.1-11

            2. Yukari Totsuka, Yingsong Lin, Yutong He, Kousuke Ishino, Haruna Sato, Mamoru Kato, Momoko Nagai, Asmaa Elzawahry, Yasushi Totoki, Hiromi Nakamura, Fumie Hosoda, Tatsuhiro Shibata, Tomonari Matsuda, Yoshitaka Matsushima, Guohui Song, Fanshu Meng, Dongfang Li, Junfeng Liu, Youlin Qiao, Wenqiang Wei, Manami Inoue, Shogo Kikuchi, Hitoshi Nakagama, Baoen Shan
              DNA Adductome Analysis Identifies N-Nitrosopiperidine Involved in the Etiology of Esophageal Cancer in Cixian, China
              Chem Res Toxicol, 2019, 32, 1515.1-13

    2018

            1. Masaya Sekimizu, Akihiko Yoshida, Sachiyo Mitani, Naofumi Asano, Makoto Hirata, Takashi Kubo, Fumito Yamazaki, Hiromi Sakamoto, Mamoru Kato, Naohiro Makise, Taisuke Mori, Naoya Yamazaki, Shigeki Sekine, Ichiro Oda, Shun-ichi Watanabe, Hiroaki Hiraga, Tsukasa Yonemoto, Teruya Kawamoto, Norifumi Naka, Yuki Funauchi, Yoshihiro Nishida, Kanya Honoki, Hirotaka Kawano, Hiroyuki Tsuchiya, Toshiyuki Kunisada , Koichi Matsuda, Katsunori Inagaki, Akira Kawai, Hitoshi Ichikawa
              Frequent mutations of genes encoding vacuolar H+-ATPase components in granular cell tumors
              Genes, Chromosomes & Cancer, 2018, 58, 373.1-8

            2. Kohei Fukuoka, Yonehiro Kanemura, Tomoko Shofuda, Shintaro Fukushima, Satoshi Yamashita, Daichi Narushima, Mamoru Kato, Mai Honda-Kitahara, Hitoshi Ichikawa, Takashi Kohno, Atsushi Sasaki, Junko Hirato, Takanori Hirose, Takashi Komori, Kaishi Satomi, Akihiko Yoshida, Kai Yamasaki, Yoshiko Nakano, Ai Takada, Taishi Nakamura, Hirokazu Takami, Yuko Matsushita, Tomonari Suzuki, Hideo Nakamura, Keishi Makino, Yukihiko Sonoda, Ryuta Saito, Teiji Tominaga, Yasuhiro Matsusaka, Keiichi Kobayashi, Motoo Nagane, Takuya Furuta, Mitsutoshi Nakada, Yoshitaka Narita, Yuichi Hirose, Shigeo Ohba, Akira Wada, Katsuyoshi Shimizu, Kazuhiko Kurozumi, Isao Date, Junya Fukai, Yousuke Miyairi, Naoki Kagawa, Atsushi Kawamura, Makiko Yoshida, Namiko Nishida, Takafumi Wataya, Masayoshi Yamaoka, Naohiro Tsuyuguchi, Takehiro Uda, Mayu Takahashi, Yoshiteru Nakano, Takuya Akai, Shuichi Izumoto, Masahiro Nonaka, Kazuhisa Yoshifuji, Yoshinori Kodama, Masayuki Mano, Tatsuya Ozawa, Vijay Ramaswamy, Michael D. Taylor, Toshikazu Ushijima, Soichiro Shibui, Mami Yamasaki, Hajime Arai, Hiroaki Sakamoto, Ryo Nishikawa, Koichi Ichimura
              Significance of molecular classification in ependymomas: C11orf95-RELA fusion-negative supratentorial ependymomas are a heterogenous group of tumor
              Acta Neuropathologica Communications, 2018, 6, 134.1-18
            3. Kota Itahashi, Shunsuke Kondo, Takashi Kubo, Yutaka Fujiwara, Mamoru Kato, Hitoshi Ichikawa, Takahiko Koyama, Reitaro Tokumasu, Jia Xu, Claudia S. Huettner, Vanessa V. Michelinim, Laxmi Parida, Takashi Kohno, and Noboru Yamamoto
              Evaluating clinical genome sequence analysis by Watson for Genomics
              Frontiers in Medicine, 2018, 5, 305.1-10

            4. Endi Xia, Sotaro Kanematsu, Yusuke Suenaga, Asmaa Elzawahry, Hitomi Kondo, Noriko Otsuka, Yasumitsu Moriya, Toshihiko Iizasa, Mamoru Kato, Ichiro Yoshino, and Sana Yokoi
              MicroRNA induction by copy number gain is associated with poor outcome in squamous cell carcinoma of the lung
              Scientific Reports, 2018, 8, 15363.1-10

            5. Tomoko Saito, Atsushi Niida, Ryutaro Uchi, Hidenari Hirata, Hisateru Komatsu, Shotaro Sakimura, Shuto Hayashi, Sho Nambara, Yosuke Kuroda, Shuhei Ito, Hidetoshi Eguchi, Takaaki Masuda, Keishi Sugimachi, Taro Tobo, Haruto Nishida, Tsutomu Daa, Kenichi Chiba, Yuichi Shiraishi, Tetsuichi Yoshizato, Masaaki Kodama, Tadayoshi Okimoto, Kazuhiro Mizukami, Ryo Ogawa, Kazuhisa Okamoto, Mitsutaka Shuto, Kensuke Fukuda, Yusuke Matsui, Teppei Shimamura, Takanori Hasegawa, Yuichiro Doki, Satoshi Nagayama, Kazutaka Yamada, Mamoru Kato, Tatsuhiro Shibata, Masaki Mori, Hiroyuki Aburatani, Kazunari Murakami, Yutaka Suzuki, Seishi Ogawa, Satoru Miyano, and Koshi Mimori
              A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer
              Nature Communications, 2018, 9, 2884.1-11

            6. Eri Arai, Fumihito Miura, Yasushi Totoki, Satoshi Yamashita, Ying Tian, Masahiro Gotoh, Hidenori Ojima, Hiroyuki Nakagawa, Yoriko Takahashi, Hiromi Nakamura, Natsuko Hama, Mamoru Kato, Hiroshi Kimura, Yutaka Suzuki, Takashi Ito, Tatsuhiro Shibata, and Yae Kanai
              Epigenome mapping of human normal purified hepatocytes: personal epigenome variation and genome–epigenome correlation
              Epigenomics, 10, 955-979

            7. Mamoru Kato, Hiromi Nakamura, Momoko Nagai, Takashi Kubo, Asmaa Elzawahry, Yasushi Totoki, Yuko Tanabe, Eisaku Furukawa, Joe Miyamoto, Hiromi Sakamoto, Shingo Matsumoto, Kuniko Sunami, Yasuhito Arai, Yutaka Suzuki, Teruhiko Yoshida, Katsuya Tsuchihara, Kenji Tamura, Noboru Yamamoto, Hitoshi Ichikawa, Takashi Kohno, and Tatsuhiro Shibata
              A computational tool to detect DNA alterations tailored to formalin-fixed paraffin-embedded samples in cancer clinical sequencing
              Genome Medicine, 2018, 10, 44.1-11

            8. Jo Nishino, Yuta Kochi, Daichi Shigemizu, Mamoru Kato, Katsunori Ikari, Hidenori Ochi, Hisashi Noma, Kota Matsui, Takashi Morizono, Keith Boroevich, Tatsuhiko Tsunoda, Shigeyuki Matsui
              Empirical Bayes estimation of semi-parametric hierarchical mixture models for unbiased characterization of polygenic disease architectures
              Frontiers in Genetics, 2018, 9.1-12

            9. Koichi Ogura, Fumie Hosoda, Yasuhito Arai, Hiromi Nakamura, Natsuko Hama, Yasushi Totoki, Akihiko Yoshida, Momoko Nagai, Mamoru Kato, Shoko Ohashi, Hiroko Shimizu, Erika Arakawa, Wakako Mukai, Hirofumi Rokutan, Akira Kawai, Sakae Tanaka, Tatsuhiro Shibata
              Integrated genetic and epigenetic analysis of myxofibrosarcoma
              Nature Communications, 2018, 9, 2765.1-11

     Review Articles（総説）
            1. Mamoru Kato
              Development of bioinformatics methods in cancer gene-panel test
              Precision Medicine (in Japanese), NTS, ISBN 978-4-86043-580-6, 2018, 71-80
              加藤　護
              がん遺伝子パネル検査におけるバイオインフォマティクス分析手法の開発、
              プレシジョン・メディシン、NTS, ISBN 978-4-86043-580-6, 2018, 71-80
            2. Mamoru Kato
              Bioinformatics pipelines in genome medicine
              Experimental Medicine (Jikken Igaku, in Japanese), 2018, 36, 2645-2652
              加藤　護
              ゲノム医療のバイオインフォマティクス・パイプライン、
              実験医学、2018, 36, 2645-2652

    2017

            1. Mamoru Kato, Daniel A. Vasco, Ryuichi Sugino, Daichi Narushima, and Alexander Krasnitz
              Sweepstake evolution revealed by population-genetic analysis of copy-number alterations in single genomes of breast cancer
              Royal Society Open Science, 2017, 4, 171060.1-11
            2. Daisuke Shiokawa, Hirokazu Ohata, Ai Sato, Michihiro Muto, Shigeki Sekine, Masahito Hosokawa, Mamoru Kato, Hideki Kanbara, Tatsuhiro Shibata, Koji Okamoto
              The induction of selected Wnt target genes by Tcf1 mediates generation of tumorigenic colon stem cells
              Cell Reports, 2017, 19, 981-994
            3. Shigeki Sekine, Taisuke Mori, Reiko Ogawa, Masahiro Tanaka, Hiroshi Yoshida, Hirokazu Taniguchi, Takeshi Nakajima, Kokichi Sugano, Teruhiko Yoshida, Mamoru Kato, Eisaku Furukawa, Atsushi Ochiai, and Nobuyoshi Hiraoka
              Mismatch repair deficiency commonly precedes adenoma formation in Lynch syndrome-associated colorectal tumorigenesis
              Modern Pathology, 2017, 30, 1144-1151
            4. Shintaro Fukushima, Satoshi Yamashita, Hisato Kobayashi, Hirokazu Takami, Kohei Fukuoka, Taishi Nakamura, Kai Yamasaki, Yuko Matsushita, Hiromi Nakamura, Yasushi Totoki, Mamoru Kato, Tomonari Suzuki, Kazuhiko Mishima, Takaaki Yanagisawa, Akitake Mukasa, Nobuhito Saito, Masayuki Kanamori, Toshihiro Kumabe, Teiji Tominaga, Motoo Nagane, Toshihiko Iuchi, Koji Yoshimoto, Masahiro Mizoguchi, Kaoru Tamura, Keiichi Sakai, Kazuhiko Sugiyama, Mitsutoshi Nakada, Kiyotaka Yokogami, Hideo Takeshima, Yonehiro Kanemura, Masahide Matsuda, Akira Matsumura, Kazuhiko Kurozumi, Keisuke Ueki, Masahiro Nonaka, Akio Asai, Nobutaka Kawahara, Yuichi Hirose, Tatusya Takayama, Yoichi Nakazato, Yoshitaka Narita, Tatsuhiro Shibata, Masao Matsutani, Toshikazu Ushijima, Ryo Nishikawa, Koichi Ichimura, On behalf of The Intracranial Germ Cell Tumor Genome Analysis Consortium (The iGCTConsortium)
              Genome‑wide methylation profiles in primary intracranial germ cell tumors indicate a primordial germ cell origin for germinomas
              Acta Neuropathologica, 2017, 133, 445-462
            5. Tsuyoshi Takahashi, Asmaa Elzawahry, Sachiyo Mimaki, Eisaku Furukawa, Rie Nakatsuka, Hiromi Nakamura, Takahiko Nishigaki, Satoshi Serada, Tetsuji Naka, Seiichi Hirota, Tatsuhiro Shibata, Katsuya Tsuchihara, Toshirou Nishida, and Mamoru Kato
              Genomic and transcriptomic analysis of imatinib resistance in gastrointestinal stromal tumors
              Genes, Chromosomes & Cancer, 2017, 56, 303-313
            6. Naofumi Asano, Akihiko Yoshida, Sachiyo Mitani, Eisuke Kobayashi, Bunsyo Shiotani, Motokiyo Komiyama, Hiroyuki Fujimoto, Hirokazu Chuman, Hideo Morioka, Morio Matsumoto, Masaya Nakamura, Takashi Kubo, Mamoru Kato, Takashi Kohno, Akira Kawai, Tadashi Kondo, and Hitoshi Ichikawa
              Frequent amplification of receptor tyrosine kinase genes in well-differentiated/dedifferentiated liposarcoma
              Oncotarget, 2017, 8, 12941-12952
            7. Hideyuki Hayashi, Takashi Kohno, Hideki Ueno, Nobuyoshi Hiraoka, Shunsuke Kondo, Motonobu Saito, Yoko Shimada, Hitoshi Ichikawa, Mamoru Kato, Tatsuhiro Shibata, Chigusa Morizane, Yasunari Sakamoto, Kazuaki Shimada, Yoshito Komatsu, Naoya Sakamoto, and Takuji Okusaka
              Utility of Assessing the Number of Mutated KRAS, CDKN2A, TP53, and SMAD4 Genes Using a Targeted Deep Sequencing Assay as a Prognostic Biomarker for Pancreatic Cancer
              Pancreas, 2017, 46, 335-340
    Review Articles（総説）
            1. Mamoru Kato
              Cancer precision medicine
              Anti-Aging Medicine (Anti-Aging Igaku, in Japanese), 2017, 13, 663-669
              加藤　護
              がんのプレシジョン・メディシン
              アンチ・エイジング医学、2017, 13, 663-669

    2016

            1. Yuko Tanabe, Hitoshi Ichikawa, Takashi Kohno, Hiroshi Yoshida, Takashi Kubo, Mamoru Kato, Satoru Iwasa, Atsushi Ochiai, Noboru Yamamoto, Yasuhiro Fujiwara, and Kenji Tamura
              Comprehensive screening of target molecules by next-generation sequencing in patients with malignant solid tumors: guiding entry into phase I clinical trials
              Molecular Cancer, 2016, 15, 73-77
            2. Koichi Ichimura, Shintaro Fukushima, Yasushi Totoki, Yuko Matsushita, Ayaka Otsuka, Arata Tomiyama, Tohru Niwa, Hirokazu Takami, Taishi Nakamura, Tomonari Suzuki, Kohei Fukuoka, Takaaki Yanagisawa, Kazuhiko Mishima, Yoichi Nakazato, Fumie Hosoda, Yoshitaka Narita, Soichiro Shibui, Akihiko Yoshida, Akitake Mukasa, Nobuhito Saito, Toshihiro Kumabe, Masayuki Kanamori, Teiji Tominaga, Keiichi Kobayashi, Saki Shimizu, Motoo Nagane, Toshihiko Iuchi, Masahiro Mizoguchi, Koji Yoshimoto, Kaoru Tamura, Taketoshi Maehara, Kazuhiko Sugiyama, Mitsutoshi Nakada, Keiichi Sakai, Yonehiro Kanemura, Masahiro Nonaka, Akio Asai, Kiyotaka Yokogami, Hideo Takeshima, Nobutaka Kawahara, Tatsuya Takayama, Masahiro Yao, Mamoru Kato, Hiromi Nakamura, Natsuko Hama, Ryuichi Sakai, Toshikazu Ushijima, Masao Matsutani, Tatsuhiro Shibata, Ryo Nishikawa, The Intracranial Germ Cell Tumor Genome Analysis Consortium
              Recurrent neomorphic mutations of MTOR in central nervous system and testicular germ cell tumors may be targeted for therapy
              Acta Neuropathologica, 2016, 131, 889–901
            3. Akihiro Fujimoto+, Mayuko Furuta+, Yasushi Totoki+, Tatsuhiko Tsunoda+, Mamoru Kato+, Yuichi Shiraishi, Hiroko Tanaka, Hiroaki Taniguchi, Yoshiiku Kawakami, Masaki Ueno, Kunihito Gotoh, Shun-ichi Ariizumi, Christopher P Wardell, Shinya Hayami, Toru Nakamura, Hiroshi Aikata, Koji Arihiro, Keith A Boroevich, Tetsuo Abe, Kaoru Nakano, Kazuhiro Maejima, Aya Sasaki-Oku, Ayako Ohsawa, Tetsuo Shibuya, Hiromi Nakamura, Natsuko Hama, Fumie Hosoda, Yasuhito Arai, Shoko Ohashi, Tomoko Urushidate, Genta Nagae, Shogo Yamamoto, Hiroki Ueda, Kenji Tatsuno, Hidenori Ojima, Nobuyuki Hiraoka, Takuji Okusaka, Michiaki Kubo, Shigeru Marubashi, Terumasa Yamada, Satoshi Hirano, Masakazu Yamamoto, Hideki Ohdan, Kazuaki Shimada, Osamu Ishikawa, Hiroki Yamaue, Kazuki Chayama, Satoru Miyano, Hiroyuki Aburatani, Tatsuhiro Shibata, and Hidewaki Nakagawa
              Whole genome mutational landscape and characterization of non-coding and structural mutations in liver cancer
              Nature Genetics, 2016, 48, 500-509
            4. Ryutaro Uchi, Yusuke Takahashi, Atsushi Niida, Teppei Shimamura, Hidenari Hirata, Keishi Sugimachi, Genta Sawada, Takeshi Iwaya, Junji Kurashige, Yoshiaki Shinden, Tomohiro Iguchi, Hidetoshi Eguchi, Kenichi Chiba, Yuichi Shiraishi, Genta Nagae, Kenichi Yoshida, Yasunobu Nagata, Hiroshi Haeno, Hirofumi Yamamoto, Hideshi Ishii, Yuichiro Doki, Hisae Iinuma, Shin Sasaki, Satoshi Nagayama, Kazutaka Yamada, Shinichi Yachida, Mamoru Kato, Tatsuhiro Shibata, Eiji Oki, Hiroshi Saeki, Ken Shirabe, Yoshinao Oda, Yoshihiko Maehara, Shizuo Komune, Masaki Mori, Yutaka Suzuki, Ken Yamamoto, Hiroyuki Aburatani, Seishi Ogawa, Satoru Miyano, and Koshi Mimori
              Integrated multiregional analysis proposing a new model of colorectal cancer evolution
              PLOS Genetics, 2016, 12, e1005778.1-24
            5. Shinichi Yachida, Laura D. Wood, Masami Suzuki, Erina Takai, Yasushi Totoki, Mamoru Kato, Claudio Luchini, Yasuhito Arai, Hiromi Nakamura, Natsuko Hama, Asmaa Elzawahry, Fumie Hosoda, Tomoki Shirota, Nobuhiko Morimoto, Kunio Hori, Jun Funazaki, Hikaru Tanaka, Chigusa Morizane, Takuji Okusaka, Satoshi Nara, Kazuaki Shimada, Nobuyoshi Hiraoka, Hirokazu Taniguchi, Ryota Higuchi, Minoru Oshima, Keiichi Okano, Seiko Hirono, Masamichi Mizuma, Koji Arihiro, Masakazu Yamamoto, Michiaki Unno, Hiroki Yamaue, Matthew J. Weiss, Christopher L. Wolfgang, Toru Furukawa, Hitoshi Nakagama, Bert Vogelstein, Tohru Kiyono, Ralph H. Hruban, and Tatsuhiro Shibata
              Genomic sequencing identifies ELF3 as a driver of ampullary carcinoma
              Cancer Cell, 2016, 29, 229-240
    Review Articles（総説）
            1. Mamoru Kato
              The current status and future prospects of biomarker exploration for cancer by bioinformatics analysis
              Pharma Medica (Pharma Medica, in Japanese), 2016, 34, 45-51
              加藤　護
               バイオインフォマティクス解析によるがんバイオマーカー探索の現状と今後の展望
              Pharma Medica、2016, 34, 45-51
            2. Mamoru Kato
              Data analysis of single-cell sequencing
              Journal of Clinical and Experimental Medicine (Igaku-no Ayumi, in Japanese), 2016, 258, 317-323
              加藤　護
               一細胞シークエンスのデータ解析
              医学のあゆみ、2016, 258, 317-323
            3. Mamoru Kato
              Bioinformatics in cancer clinical sequencing – an emerging field of cancer personalized medicine
              Japanese Journal of Cancer and Chemotherapy (Gan To Kagaku Ryouhou, in Japanese), 2016, 43, 391-397
              加藤　護
               最新がん個別化医療―臨床シークエンスのバイオインフォマティクス
              癌と化学療法、2016, 43, 391-397

    2015

            1. Erina Takai, Yasushi Totoki, Hiromi Nakamura, Chigusa Morizane, Satoshi Nara, Natsuko Hama, Masami Suzuki, Eisaku Furukawa, Mamoru Kato, Hideyuki Hayashi, Takashi Kohno, Hideki Ueno, Kazuaki Shimada, Takuji Okusaka, Hitoshi Nakagama, Tatsuhiro Shibata, and Shinichi Yachida
              Clinical utility of circulating tumor DNA for molecular assessment in pancreatic cancer
              Scientific Reports, 2015, 5, 18425.1-10
            2. Hiromi Nakamura, Yasuhito Arai, Yasushi Totoki, Tomoki Shirota, Asmaa Elzawahry, Mamoru Kato, Natsuko Hama, Fumie Hosoda, Tomoko Urushidate, Shoko Ohashi, Nobuyoshi Hiraoka, Hidenori Ojima, Kazuaki Shimada, Takuji Okusaka, Tomoo Kosuge, Shinichi Miyagawa, Tatsuhiro Shibata
              Genomic spectra of biliary tract cancer
              Nature Genetics, 2015, 47, 1003-1010
            3. Motonobu Saito, Yoko Shimada, Kouya Shiraishi, Hiromi Sakamoto, Koji Tsuta, Hirohiko Totsuka, Suenori Chiku, Hitoshi Ichikawa, Mamoru Kato, Shun-ichi Watanabe, Teruhiko Yoshida, Jun Yokota, Takashi Kohno
              Development of Lung Adenocarcinomas with Wxclusie Dependence on Oncogene Fusions
              Cancer Research, 2015, 75, 2264-2271
            4. Masataka Takenaka, Motonobu Saito, Reika Iwakawa, Nozomu Yanaihara, Misato Saito, Mamoru Kato, Hitoshi Ichikawa, Tatsuhiro Shibata, Jun Yokota, Aikou Okamoto, Takashi Kohno
              Profiling of actionable gene alterations in ovarian cancer by targeted deep sequencing
              International Journal of Oncology, 2015, 46, 2389-2398
            5. Kousuke Ishino, Tatsuya Kato, Mamoru Kato, Tatsuhiro Shibata, Masatoshi Watanabe, Keiji Wakabayashi, Hitoshi Nakagama, Yukari Totsuka
              Comprehensive DNA adduct analysis reveals pulmonary inflammatory response contributes to genotoxic action of magnetite nanoparticles
              Int. J. Mol. Sci., 2015, 16, 3474-3492

    2014

            1. Yasushi Totoki, Kenji Tatsuno, Kyle R Covington, Hiroki Ueda, Chad J Creighton, Mamoru Kato, Shingo Tsuji, Lawrence A Donehower, Betty L Slagle, Hiromi Nakamura, Shogo Yamamoto, Eve Shinbrot, Natsuko Hama, Megan Lehmkuhl, Fumie Hosoda, Yasuhito Arai, Kim Walker, Mahmoud Dahdouli, Kengo Gotoh, Genta Nagae, Marie-Claude Gingras, Donna M Muzny, Hidenori Ojima, Kazuaki Shimada, Yutaka Midorikawa, John A Goss, Ronald Cotton, Akimasa Hayashi, Junji Shibahara, Shumpei Ishikawa, Jacfranz Guiteau, Mariko Tanaka, Tomoko Urushidate, Shoko Ohashi, Naoko Okada, Harsha Doddapaneni, Min Wang, Yiming Zhu, Huyen Dinh, Takuji Okusaka, Norihiro Kokudo, Tomoo Kosuge, Tadatoshi Takayama, Masashi Fukayama, Richard A Gibbs, David A Wheeler, Hiroyuki Aburatani & Tatsuhiro Shibata
              Trans-ancestry mutational landscape of hepatocellular carcinoma genomes
              Nature Genetics, 2014, 46, 1267-1273
            2. Tatsuji Mizukami, Kouya Shiraishi, Yoko Shimada, Hideaki Ogiwara, Koji Tsuta, Hitoshi Ichikawa, Hiromi Sakamoto, Mamoru Kato, Tatsuhiro Shibata, Takashi Nakano, Takashi Kohno
              Molecular mechanisms underlying oncogenic RET fusion in lung adenocarcinoma
              Journal of Thoracic Oncology, 2014, 9, 622-630
            3. Shintaro Fukushima, Ayaka Otsuka, Tomonari Suzuki, Takaaki Yanagisawa, Kazuhiko Mishima, Akitake Mukasa, Nobuhito Saito, Toshihiro Kumabe, Masayuki Kanamori, Teiji Tominaga, Yoshitaka Narita, Soichiro Shibui, Mamoru Kato, Tatsuhiro Shibata, Masao Matsutani, Ryo Nishikawa, Koichi Ichimura, On behalf of the Intracranial Germ Cell Tumor Genome Analysis Consortium (iGCT Consortium)
              Mutually exclusive mutations of KIT and RAS are associated with KIT mRNA expression and chromosomal instability in primary intracranial pure germinomas
              Acta Neuropathologica, 2014, 127, 911-925
            4. Yusuke Suenaga, S. M. Rafiqul Islam, Jennifer Alagu, Yoshiki Kaneko, Mamoru Kato, Yukichi Tanaka, Hidetada Kawana, Shamim Hossain, Daisuke Matsumoto, Mami Yamamoto, Wataru Shoji, Makiko Itami, Tatsuhiro Shibata, Yohko Nakamura, Miki Ohira, Seiki Haraguchi, Atsushi Takatori, Akira Nakagawara
              NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3β resulting in the stabilization of MYCN in human neuroblastomas
              PLoS Genetics, 2014, 10, e1003996.1-14
    Review Articles（総説）
            1. Mamoru Kato
              Single-cell genomics of cancer
              Journal of Clinical and Experimental Medicine (Igaku-no Ayumi, in Japanese), 2014, 249, 1088-1092
              加藤　護
              一細胞ゲノム解析
              医学のあゆみ、2014, 249, 1088-1092
            2. Translation: Mamoru Kato
              Identification of oncogenic driver mutations by David Tamborero, Abel Gonzalez-Perez, and Nuria Lopez-Bigas
              Experimental Medicine (Jikken Igaku, in Japanese), 2014, 32, 213-219
              翻訳：加藤　護
              発がんドライバー変異の同定  by David Tamborero, Abel Gonzalez-Perez, and Nuria Lopez-Bigas
              実験医学、2014, 32, 213-219

    2013 or before

    https://mkato3000.wixsite.com/mysite/papers

    • Our Research Focus