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論文業績

2026年

    1. Shoji, K., Yoshida, K., Iyoda, S., Ishikawa, M., Tanaka, M., Nobe, M., Saito, N., Shino, Y., Nannya, Y., Yamato, G., Tsujimoto, S., Shiba, N., Hayashi, Y., Shiozawa, Y., Shiraishi, Y., Chiba, K., Okada, A., Tanaka, H., Miyano, S., Koga, Y., Goto, H., Terui, K., Ito, E., Kiyokawa, N., Tomizawa, D., Taga, T., Moritake, H., Tawa, A., Takita, J., Nishikori, M., Adachi, S., Ogawa, S., Matsuo, H.: Age-specific mutation profiles and their prognostic implications in pediatric KMT2A-rearranged acute myeloid leukemia. Haematologica, (2026).
    2. Yoshida, K.: Somatic mutations and clonal evolution in normal tissues and cancer development. Exp Mol Med, (2026).
    3. Nishimura, K., Isobe, T., Shigehiro, T., Nomura, M., Zang, W., Xiao, M., Liao, W., Koike, Y., Nishimura, A., Sato-Otsubo, A., Yamazaki, H., Ito, H., Okada, S., Matsumoto, N., Saika, W., Zhang, Y., Aoyama, Y., Hasegawa, C., Yamasaki, T., Kubota, Y., Oki, K., Kiyokawa, N., Nagae, G., Yoshida, K., Nannya, Y., Ueno, H., Fukuda, S., Tatsuno, K., Tsutsumi, S., Shiozawa, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Eguchi, M., Arakawa, Y., Koh, K., Deguchi, T., Tomizawa, D., Miyamura, T., Ishii, E., Mizutani, S., Miyano, S., Aburatani, H., Ogawa, S., Takaori-Kondo, A., Yokoyama, A., Abdel-Wahab, O., Ernst, P., Takita, J., Ikawa, T., Takagi, M., Inoue, D.: Comprehensive Molecular and Functional Analysis of NUTM1-Rearranged Leukemia. Blood, (2026).
    4. Kanezaki, R., Toki, T., Okuse, R., Kobayashi, A., Sato, M., Kimura, S., Kudo, K., Sato, T., Tanaka, T., Yoshida, K., Kawai, Y., Tokunaga, K., Takita, J., Ogawa, S., Terui, K., Ito, E.: Functional impact of a deep intronic variant in the RPS19 gene detected in a case of Diamond-Blackfan anemia syndrome. Haematologica, (2026).
    5. Mimura, K., Kaino, A., Ochi, Y., Chang, Y. H., Seki, M., Takeda, J., Katayama, S., Niizuma, H., Sasahara, Y., Mizoguchi, Y., Shimomura, M., Koyamada, R., Ono, R., Hasegawa, D., Mitani, K., Kubota, H., Yoshihara, S., Hiramoto, N., Otsuki, A., Okamura, Y., Katsuoka, F., Kinoshita, K., Hasegawa, M., Togo-Ohno, M., Maeda, H., Kakiuchi, N., Takeuchi, M., Sato-Otsubo, A., Kato, S., Watanabe, K., Katayama, K., Imoto, S., Shiraishi, Y., Koh, K., Suenobu, S., Hiyama, E., Goyama, S., Kikuchi, A., Ogawa, S., Kato, M., Nannya, Y., Takita, J., Yoshida, K.: BCL11B enhancer hijacking by t(14;16)(q32;q24) translocation defines a novel high-risk subtype of T-ALL. Blood, (2026).

2025年

    1. Spencer Chapman, M., Mitchell, E., Yoshida K., Williams, N., Fabre, M. A., Ranzoni, A. M., Robinson, P. S., Kregar, L. D., Wilk, M., Boettcher, S., Mahbubani, K., Saeb Parsy, K., Gowers, K. H. C., Janes, S. M., Ng, S. W. K., Hoare, M., Green, A. R., Vassiliou, G. S., Cvejic, A., Manz, M. G., Laurenti, E., Martincorena, I., Stratton, M. R., Nangalia, J., Coorens, T. H. H., Campbell, P. J.: Prolonged persistence of mutagenic DNA lesions in somatic cells. Nature, 638:729-738 (2025).
    2. Yoshida K. Clonal hematopoiesis in cancer predisposition syndromes. Int J Hematol., 122: 351-357 (2025).
    3. Mimura, K., Yoshida, K.: The Genetic Footprint of Tobacco Smoking: Unraveling the Mutational Signatures in Head and Neck Cancer. Cancer Res, 85: 2781-2783 (2025).

2024年

    1. Halik, A., Tilgner, M., Silva, P., Estrada, N., Altwasser, R., Jahn, E., Heuser, M., Hou, H. A., Pratcorona, M., Hills, R. K., Metzeler, K. H., Fenwarth, L., Dolnik, A., Terre, C., Kopp, K., Blau, O., Szyska, M., Christen, F., Kronke, J., Vasseur, L., Lowenberg, B., Esteve, J., Valk, P. J. M., Duchmann, M., Chou, W. C., Linch, D. C., Dohner, H., Gale, R. E., Dohner, K., Bullinger, L., Yoshida K., Damm, F.: Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients. J Hematol Oncol, 17: 70 (2024).
    2. Noerenberg, D., Briest, F., Hennch, C., Yoshida K., Hablesreiter, R., Takeuchi, Y., Ueno, H., Staiger, A. M., Ziepert, M., Asmar, F., Locher, B. N., Toth, E., Weber, T., Amini, R. M., Klapper, W., Bouzani, M., Poeschel, V., Rosenwald, A., Held, G., Campo, E., Ishaque, N., Stamatopoulos, K., Kanellis, G., Anagnostopoulos, I., Bullinger, L., Goldschmidt, N., Zinzani, P. L., Bodor, C., Rosenquist, R., Vassilakopoulos, T. P., Ott, G., Ogawa, S., Damm, F.: Genetic Characterization of Primary Mediastinal B-Cell Lymphoma: Pathogenesis and Patient Outcomes. J Clin Oncol, 42:452-466 (2024).
    3. Aoki, T., Shiba, N., Tsujimoto, S., Yamato, G., Hara, Y., Kato, S., Yoshida K., Ogawa, S., Hayashi, Y., Iwamoto, S., Taki, T., Shimada, A., Iijima-Yamashita, Y., Horibe, K., Tawa, A., Taga, T., Adachi, S., Tomizawa, D.: High IL2RA/CD25 expression is a prognostic stem cell biomarker for pediatric acute myeloid leukemia without a core-binding factor. Pediatr Blood Cancer, 71:e30803 (2024).
    4. Iyoda, S., Yoshida K., Shoji, K., Ito, N., Tanaka, M., Nannya, Y., Yamato, G., Tsujimoto, S., Shiba, N., Hayashi, Y., Shiozawa, Y., Shiraishi, Y., Chiba, K., Okada, A., Tanaka, H., Miyano, S., Koga, Y., Goto, H., Moritake, H., Terui, K., Ito, E., Kiyokawa, N., Tomizawa, D., Taga, T., Tawa, A., Takita, J., Nishikori, M., Adachi, S., Ogawa, S., Matsuo, H.: KRAS G12 mutations as adverse prognostic factors in KMT2A-rearranged acute myeloid leukemia. Leukemia, 38:1609-1612 (2024).
    5. Sato, T., Yoshida K., Toki, T., Kanezaki, R., Terui, K., Saiki, R., Ojima, M., Ochi, Y., Mizuno, S., Yoshihara, M., Uechi, T., Kenmochi, N., Tanaka, S., Matsubayashi, J., Kisai, K., Kudo, K., Yuzawa, K., Takahashi, Y., Tanaka, T., Yamamoto, Y., Kobayashi, A., Kamio, T., Sasaki, S., Shiraishi, Y., Chiba, K., Tanaka, H., Muramatsu, H., Hama, A., Hasegawa, D., Sato, A., Koh, K., Karakawa, S., Kobayashi, M., Hara, J., Taneyama, Y., Imai, C., Hasegawa, D., Fujita, N., Yoshitomi, M., Iwamoto, S., Yamato, G., Saida, S., Kiyokawa, N., Deguchi, T., Ito, M., Matsuo, H., Adachi, S. P., Hayashi, Y., Taga, T., Moriya Saito, A., Horibe, K., Watanabe, K., Tomizawa, D., Miyano, S., Takahashi, S., Ogawa, S., Ito, E.: Landscape of driver mutations and their clinical effects on Down syndrome-related myeloid neoplasms. Blood, 143:2627-2643 (2024).

2023年

    1. Makishima, H., Saiki, R., Nannya, Y., Korotev, S. C., Gurnari, C., Takeda, J., Momozawa, Y., Best, S., Krishnamurthy, P., Yoshizato, T., Atsuta, Y., Shiozawa, Y., Iijima-Yamashita, Y., Yoshida K., Shiraishi, Y., Nagata, Y., Kakiuchi, N., Onizuka, M., Chiba, K., Tanaka, H., Kon, A., Ochi, Y., Nakagawa, M. M., Okuda, R., Mori, T., Yoda, A., Itonaga, H., Miyazaki, Y., Sanada, M., Ishikawa, T., Chiba, S., Tsurumi, H., Kasahara, S., Muller-Tidow, C., Takaori-Kondo, A., Ohyashiki, K., Kiguchi, T., Matsuda, F., Jansen, J. H., Polprasert, C., Blombery, P., Kamatani, Y., Miyano, S., Malcovati, L., Haferlach, T., Kubo, M., Cazzola, M., Kulasekararaj, A. G., Godley, L. A., Maciejewski, J. P., Ogawa, S.: Germline DDX41 mutations define a unique subtype of myeloid neoplasms. Blood, 141: 534-549 (2023).
    2. Kaburagi, T., Shiba, N., Yamato, G., Yoshida K., Tabuchi, K., Ohki, K., Ishikita, E., Hara, Y., Shiraishi, Y., Kawasaki, H., Sotomatsu, M., Takizawa, T., Taki, T., Kiyokawa, N., Tomizawa, D., Horibe, K., Miyano, S., Taga, T., Adachi, S., Ogawa, S., Hayashi, Y.: UBTF-internal tandem duplication as a novel poor prognostic factor in pediatric acute myeloid leukemia. Genes Chromosomes Cancer, 62: 202-209 (2023).
    3. Nishimura, T., Kakiuchi, N., Yoshida, K., Sakurai, T., Kataoka, T. R., Kondoh, E., Chigusa, Y., Kawai, M., Sawada, M., Inoue, T., Takeuchi, Y., Maeda, H., Baba, S., Shiozawa, Y., Saiki, R., Nakagawa, M. M., Nannya, Y., Ochi, Y., Hirano, T., Nakagawa, T., Inagaki-Kawata, Y., Aoki, K., Hirata, M., Nanki, K., Matano, M., Saito, M., Suzuki, E., Takada, M., Kawashima, M., Kawaguchi, K., Chiba, K., Shiraishi, Y., Takita, J., Miyano, S., Mandai, M., Sato, T., Takeuchi, K., Haga, H., Toi, M., Ogawa, S.: Evolutionary histories of breast cancer and related clones. Nature, 620: 607-614 (2023)
    4. Briest, F., Noerenberg, D., Hennch, C., Yoshida K., Hablesreiter, R., Nimo, J., Sasca, D., Kirchner, M., Mansouri, L., Inoue, Y., Wiegand, L., Staiger, AM., Casadei, B., Korkolopoulou, P., Weiner, J., Lopez-Guillermo, A., Warth, A., Schneider, T., Nagy, Á., Klapper, W., Hummel, M., Kanellis, G., Anagnostopoulos, I., Mertins, P., Bullinger, L., Rosenquist, R., Vassilakopoulos, TP., Ott, G., Ogawa, S., Damm, F.: Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma. Leukemia, 37: 2237-2249 (2023)
    5. Hara, Y., Shiba, N., Yoshida K., Yamato, G., Kaburagi, T., Shiraishi, Y., Ohki, K., Shiozawa, Y., Kawamura, M., Kawasaki, H., Sotomatsu, M., Takizawa, T., Matsuo, H., Shimada, A., Kiyokawa, N., Tomizawa, D., Taga, T., Ito, E., Horibe, K., Miyano, S., Adachi, S., Taki, T., Ogawa, S., Hayashi, Y.: TP53 and RB1 alterations characterize poor prognostic subgroups in pediatric acute myeloid leukemia. Genes Chromosomes Cancer, 62: 412-422 (2023).
    6. Nannya, Y., Tobiasson, M., Sato, S., Bernard, E., Ohtake, S., Takeda, J., Creignou, M., Zhao, L., Kusakabe, M., Shibata, Y., Nakamura, N., Watanabe, M., Hiramoto, N., Shiozawa, Y., Shiraishi, Y., Tanaka, H., Yoshida K., Kakiuchi, N., Makishima, H., Nakagawa, M., Usuki, K., Watanabe, M., Imada, K., Handa, H., Taguchi, M., Kiguchi, T., Ohyashiki, K., Ishikawa, T., Takaori-Kondo, A., Tsurumi, H., Kasahara, S., Chiba, S., Naoe, T., Miyano, S., Papaemanuil, E., Miyazaki, Y., Hellstrom-Lindberg, E., Ogawa, S.: Postazacitidine clone size predicts long-term outcome of patients with myelodysplastic syndromes and related myeloid neoplasms. Blood Adv, 7: 3624-3636 (2023).
    7. Takagi, M., Hoshino, A., Bousset, K., Roddecke, J., Martin, H. L., Folcut, I., Tomomasa, D., Yang, X., Kobayashi, J., Sakata, N., Yoshida K., Miyano, S., Ogawa, S., Kojima, S., Morio, T., Dork, T., Kanegane, H.: Bone Marrow Failure and Immunodeficiency Associated with Human RAD50 Variants. J Clin Immunol, 43: 2136-2145 (2023).

2022年

    1. Yamato, G., Kawai, T., Shiba, N., Ikeda, J., Hara, Y., Ohki, K., Tsujimoto, S. I., Kaburagi, T., Yoshida K., Shiraishi, Y., Miyano, S., Kiyokawa, N., Tomizawa, D., Shimada, A., Sotomatsu, M., Arakawa, H., Adachi, S., Taga, T., Horibe, K., Ogawa, S., Hata, K., Hayashi, Y.: Genome-wide DNA Methylation Analysis in Pediatric Acute Myeloid Leukemia. Blood Adv,  (2022).
    2. Yaguchi, T., Kimura, S., Sekiguchi, M., Kubota, Y., Seki, M., Yoshida K., Shiraishi, Y., Kataoka, K., Fujii, Y., Watanabe, K., Hiwatari, M., Miyano, S., Ogawa, S., Takita, J.: Description of longitudinal tumor evolution in a case of multiply relapsed clear cell sarcoma of the kidney. Cancer Rep (Hoboken),   (2022).
    3. Takeuchi, Y., Yoshida K., Halik, A., Kunitz, A., Suzuki, H., Kakiuchi, N., Shiozawa, Y., Yokoyama, A., Inoue, Y., Hirano, T., Yoshizato, T., Aoki, K., Fujii, Y., Nannya, Y., Makishima, H., Pfitzner, B. M., Bullinger, L., Hirata, M., Jinnouchi, K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Okamoto, T., Haga, H., Ogawa, S., Damm, F.: The landscape of genetic aberrations in myxofibrosarcoma. Int J Cancer,   (2022).
    4. Takeda, J., Yoshida K., Nakagawa, M. M., Nannya, Y., Yoda, A., Saiki, R., Ochi, Y., Zhao, L., Okuda, R., Qi, X., Mori, T., Kon, A., Chiba, K., Tanaka, H., Shiraishi, Y., Kuo, M. C., Kerr, C. M., Nagata, Y., Morishita, D., Hiramoto, N., Hangaishi, A., Nakazawa, H., Ishiyama, K., Miyano, S., Chiba, S., Miyazaki, Y., Kitano, T., Usuki, K., Sezaki, N., Tsurumi, H., Miyawaki, S., Maciejewski, J. P., Ishikawa, T., Ohyashiki, K., Ganser, A., Heuser, M., Thol, F., Shih, L. Y., Takaori-Kondo, A., Makishima, H., Ogawa, S.: Amplified EPOR/JAK2 Genes Define a Unique Subtype of Acute Erythroid Leukemia. Blood Cancer Discov,   (2022).
    5. Kaburagi, T., Yamato, G., Shiba, N., Yoshida K., Hara, Y., Tabuchi, K., Shiraishi, Y., Ohki, K., Sotomatsu, M., Arakawa, H., Matsuo, H., Shimada, A., Taki, T., Kiyokawa, N., Tomizawa, D., Horibe, K., Miyano, S., Taga, T., Adachi, S., Ogawa, S., Hayashi, Y.: Clinical significance of RAS pathway alterations in pediatric acute myeloid leukemia. Haematologica,  (2022).
    6. Isobe, T., Takagi, M., Sato-Otsubo, A., Nishimura, A., Nagae, G., Yamagishi, C., Tamura, M., Tanaka, Y., Asada, S., Takeda, R., Tsuchiya, A., Wang, X., Yoshida K., Nannya, Y., Ueno, H., Akazawa, R., Kato, I., Mikami, T., Watanabe, K., Sekiguchi, M., Seki, M., Kimura, S., Hiwatari, M., Kato, M., Fukuda, S., Tatsuno, K., Tsutsumi, S., Kanai, A., Inaba, T., Shiozawa, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Kotecha, R. S., Cruickshank, M. N., Ishikawa, F., Morio, T., Eguchi, M., Deguchi, T., Kiyokawa, N., Arakawa, Y., Koh, K., Aoki, Y., Ishihara, T., Tomizawa, D., Miyamura, T., Ishii, E., Mizutani, S., Wilson, N. K., Gottgens, B., Miyano, S., Kitamura, T., Goyama, S., Yokoyama, A., Aburatani, H., Ogawa, S., Takita, J.: Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia. Nat Commun,   (2022).

2021年

    1. Fujii, Y., Sato, Y., Suzuki, H., Kakiuchi, N., Yoshizato, T., Lenis, A. T., Maekawa, S., Yokoyama, A., Takeuchi, Y., Inoue, Y., Ochi, Y., Shiozawa, Y., Aoki, K., Yoshida K., Kataoka, K., Nakagawa, M. M., Nannya, Y., Makishima, H., Miyakawa, J., Kawai, T., Morikawa, T., Shiraishi, Y., Chiba, K., Tanaka, H., Nagae, G., Sanada, M., Sugihara, E., Sato, T. A., Nakagawa, T., Fukayama, M., Ushiku, T., Aburatani, H., Miyano, S., Coleman, J. A., Homma, Y., Solit, D. B., Kume, H., Ogawa, S.: Molecular classification and diagnostics of upper urinary tract urothelial carcinoma. Cancer Cell, 39: 793-809 e798 (2021).
    2. Honda, T., Yamaoka, M., Terao, Y. M., Hasegawa, D., Kumamoto, T., Takagi, M., Yoshida K., Ogawa, S., Goto, H., Akiyama, M.: Successful treatment of hepatosplenic T-cell lymphoma with fludarabine, high-dose cytarabine and subsequent unrelated umbilical cord blood transplantation. Int J Hematol,   (2021).
    3. Hoyer, K., Hablesreiter, R., Inoue, Y., Yoshida K., Briest, F., Christen, F., Kakiuchi, N., Yoshizato, T., Shiozawa, Y., Shiraishi, Y., Striefler, J. K., Bischoff, S., Lohneis, P., Putter, H., Blau, O., Keilholz, U., Bullinger, L., Pelzer, U., Hummel, M., Riess, H., Ogawa, S., Sinn, M., Damm, F.: A genetically defined signature of responsiveness to erlotinib in early-stage pancreatic cancer patients: Results from the CONKO-005 trial. EBioMedicine, 66: 103327 (2021).
    4. Ishida, Y., Kakiuchi, N., Yoshida K., Inoue, Y., Irie, H., Kataoka, T. R., Hirata, M., Funakoshi, T., Matsushita, S., Hata, H., Uchi, H., Yamamoto, Y., Fujisawa, Y., Fujimura, T., Saiki, R., Takeuchi, K., Shiraishi, Y., Chiba, K., Tanaka, H., Otsuka, A., Miyano, S., Kabashima, K., Ogawa, S.: Unbiased Detection of Driver Mutations in Extramammary Paget Disease. Clin Cancer Res, 27: 1756-1765 (2021).
    5. Kaburagi, T., Yamato, G., Shiba, N., Yoshida K., Hara, Y., Tabuchi, K., Shiraishi, Y., Ohki, K., Sotomatsu, M., Arakawa, H., Matsuo, H., Shimada, A., Taki, T., Kiyokawa, N., Tomizawa, D., Horibe, K., Miyano, S., Taga, T., Adachi, S., Ogawa, S., Hayashi, Y.: Clinical significance of RAS pathway alterations in pediatric acute myeloid leukemia. Haematologica,   (2021).
    6. Kimura, S., Sekiguchi, M., Watanabe, K., Hiwatarai, M., Seki, M., Yoshida K., Isobe, T., Shiozawa, Y., Suzuki, H., Hoshino, N., Hayashi, Y., Oka, A., Miyano, S., Ogawa, S., Takita, J.: Association of high-risk neuroblastoma classification based on expression profiles with differentiation and metabolism. PLoS One, 16: e0245526 (2021).
    7. Koyamaishi, S., Kamio, T., Kobayashi, A., Sato, T., Kudo, K., Sasaki, S., Kanezaki, R., Hasegawa, D., Muramatsu, H., Takahashi, Y., Sasahara, Y., Hiramatsu, H., Kakuda, H., Tanaka, M., Ishimura, M., Nishi, M., Ishiguro, A., Yabe, H., Sarashina, T., Yamamoto, M., Yuza, Y., Hyakuna, N., Yoshida K., Kanno, H., Ohga, S., Ohara, A., Kojima, S., Miyano, S., Ogawa, S., Toki, T., Terui, K., Ito, E.: Reduced-intensity conditioning is effective for hematopoietic stem cell transplantation in young pediatric patients with Diamond-Blackfan anemia. Bone Marrow Transplant, 56: 1013-1020 (2021).
    8. Mu A, H. A., Niwa A, Osawa M, Yoshida K, Mori M, Okamoto Y, Inoue K, Kondo K, Kanemaki MT, Matsuda T, Ito E, Kojima S, Nakahata T, Ogawa S, Tanaka K, Matsuo K, Saito MK, Takata M.: Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia–like IBMFS ADH5/ALDH2 deficiency. Blood, 137: 2021-2032 (2021).
    9. Nishimura, A., Hirabayashi, S., Hasegawa, D., Yoshida K., Shiraishi, Y., Ashiarai, M., Hosoya, Y., Fujiwara, T., Harigae, H., Miyano, S., Ogawa, S., Manabe, A.: Acquisition of monosomy 7 and a RUNX1 mutation in Pearson syndrome. Pediatr Blood Cancer, 68: e28799 (2021).
    10. Ochi, Y., Yoshida K., Huang, Y. J., Kuo, M. C., Nannya, Y., Sasaki, K., Mitani, K., Hosoya, N., Hiramoto, N., Ishikawa, T., Branford, S., Shanmuganathan, N., Ohyashiki, K., Takahashi, N., Takaku, T., Tsuchiya, S., Kanemura, N., Nakamura, N., Ueda, Y., Yoshihara, S., Bera, R., Shiozawa, Y., Zhao, L., Takeda, J., Watatani, Y., Okuda, R., Makishima, H., Shiraishi, Y., Chiba, K., Tanaka, H., Sanada, M., Takaori-Kondo, A., Miyano, S., Ogawa, S., Shih, L. Y.: Clonal evolution and clinical implications of genetic abnormalities in blastic transformation of chronic myeloid leukaemia. Nat Commun, 12: 2833 (2021).
    11. Ono, R., Ueno, H., Yoshida K., Takahashi, S., Yoshihara, H., Nozaki, T., Suzuki, K., Nakazawa, A., Saiki, R., Seki, M., Takita, J., Ogawa, S., Manabe, A., Hasegawa, D.: Clonal evidence for the development of neuroblastoma with extensive copy-neutral loss of heterozygosity arising in a mature teratoma. Cancer Sci, 112: 2921-2927 (2021).
    12. Polprasert, C., Takeuchi, Y., Makishima, H., Wudhikarn, K., Kakiuchi, N., Tangnuntachai, N., Assanasen, T., Sitthi, W., Muhamad, H., Lawasut, P., Kongkiatkamon, S., Bunworasate, U., Izutsu, K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Ogawa, S., Yoshida K., Rojnuckarin, P.: Frequent mutations in HLA and related genes in extranodal NK/T cell lymphomas. Leuk Lymphoma, 62: 95-103 (2021).
    13. Sasaki, K., Tsujimoto, S., Miyake, M., Uchiyama, Y., Ikeda, J., Yoshitomi, M., Shimosato, Y., Tokumasu, M., Matsuo, H., Yoshida K., Ohki, K., Kaburagi, T., Yamato, G., Hara, Y., Takeuchi, M., Kinoshita, A., Tomizawa, D., Taga, T., Adachi, S., Tawa, A., Horibe, K., Hayashi, Y., Matsumoto, N., Ito, S., Shiba, N.: Droplet digital polymerase chain reaction assay for the detection of the minor clone of KIT D816V in paediatric acute myeloid leukaemia especially showing RUNX1-RUNX1T1 transcripts. Br J Haematol, 194: 414-422 (2021).
    14. Senda, N., Kawaguchi-Sakita, N., Kawashima, M., Inagaki-Kawata, Y., Yoshida K., Takada, M., Kataoka, M., Torii, M., Nishimura, T., Kawaguchi, K., Suzuki, E., Kataoka, Y., Matsumoto, Y., Yoshibayashi, H., Yamagami, K., Tsuyuki, S., Takahara, S., Yamauchi, A., Shinkura, N., Kato, H., Moriguchi, Y., Okamura, R., Kan, N., Suwa, H., Sakata, S., Mashima, S., Yotsumoto, F., Tachibana, T., Tanaka, M., Togashi, K., Haga, H., Yamada, T., Kosugi, S., Inamoto, T., Sugimoto, M., Ogawa, S., Toi, M.: Optimization of prediction methods for risk assessment of pathogenic germline variants in the Japanese population. Cancer Sci, 112: 3338-3348 (2021).
    15. Shimada, K., Yoshida K., Suzuki, Y., Iriyama, C., Inoue, Y., Sanada, M., Kataoka, K., Yuge, M., Takagi, Y., Kusumoto, S., Masaki, Y., Ito, T., Inagaki, Y., Okamoto, A., Kuwatsuka, Y., Nakatochi, M., Shimada, S., Miyoshi, H., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Shiozawa, Y., Nannya, Y., Okabe, A., Kohno, K., Atsuta, Y., Ohshima, K., Nakamura, S., Ogawa, S., Tomita, A., Kiyoi, H.: Frequent genetic alterations in immune checkpoint-related genes in intravascular large B-cell lymphoma. Blood, 137: 1491-1502 (2021).
    16. Spencer Chapman, M., Ranzoni, A. M., Myers, B., Williams, N., Coorens, T. H. H., Mitchell, E., Butler, T., Dawson, K. J., Hooks, Y., Moore, L., Nangalia, J., Robinson, P. S., Yoshida K., Hook, E., Campbell, P. J., Cvejic, A.: Lineage tracing of human development through somatic mutations. Nature, 595: 85-90 (2021).
    17. Yasudo, H., Ando, T., Maehara, A., Ando, T., Izawa, K., Tanabe, A., Kaitani, A., Nomura, S., Seki, M., Yoshida K., Oda, H., Okamoto, Y., Wang, H., Kamei, A., Kojima, M., Kimura, M., Uchida, K., Nakano, N., Kaneko, J., Ebihara, N., Hasegawa, K., Shimizu, T., Takita, J., Ogawa, H., Okumura, K., Ogawa, S., Tamura, N., Kitaura, J.: A Possible Association Between a Nucleotide-Binding Domain LRR-Containing Protein Family PYD-Containing Protein 1 Mutation and an Autoinflammatory Disease Involving Liver Cirrhosis. Hepatology, 74: 2296-2299 (2021).

2020年

    1. Dingler, F. A., Wang, M., Mu, A., Millington, C. L., Oberbeck, N., Watcham, S., Pontel, L. B., Kamimae-Lanning, A. N., Langevin, F., Nadler, C., Cordell, R. L., Monks, P. S., Yu, R., Wilson, N. K., Hira, A., Yoshida K., Mori, M., Okamoto, Y., Okuno, Y., Muramatsu, H., Shiraishi, Y., Kobayashi, M., Moriguchi, T., Osumi, T., Kato, M., Miyano, S., Ito, E., Kojima, S., Yabe, H., Yabe, M., Matsuo, K., Ogawa, S., Gottgens, B., Hodskinson, M. R. G., Takata, M., Patel, K. J.: Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans. Mol Cell, 80: 996-1012 e1019 (2020).
    2. Inagaki-Kawata, Y., Yoshida K., Kawaguchi-Sakita, N., Kawashima, M., Nishimura, T., Senda, N., Shiozawa, Y., Takeuchi, Y., Inoue, Y., Sato-Otsubo, A., Fujii, Y., Nannya, Y., Suzuki, E., Takada, M., Tanaka, H., Shiraishi, Y., Chiba, K., Kataoka, Y., Torii, M., Yoshibayashi, H., Yamagami, K., Okamura, R., Moriguchi, Y., Kato, H., Tsuyuki, S., Yamauchi, A., Suwa, H., Inamoto, T., Miyano, S., Ogawa, S., Toi, M.: Genetic and clinical landscape of breast cancers with germline BRCA01月02日 variants. Commun Biol, 3: 578 (2020).
    3. Kakiuchi, N., Yoshida K., Uchino, M., Kihara, T., Akaki, K., Inoue, Y., Kawada, K., Nagayama, S., Yokoyama, A., Yamamoto, S., Matsuura, M., Horimatsu, T., Hirano, T., Goto, N., Takeuchi, Y., Ochi, Y., Shiozawa, Y., Kogure, Y., Watatani, Y., Fujii, Y., Kim, S. K., Kon, A., Kataoka, K., Yoshizato, T., Nakagawa, M. M., Yoda, A., Nanya, Y., Makishima, H., Shiraishi, Y., Chiba, K., Tanaka, H., Sanada, M., Sugihara, E., Sato, T. A., Maruyama, T., Miyoshi, H., Taketo, M. M., Oishi, J., Inagaki, R., Ueda, Y., Okamoto, S., Okajima, H., Sakai, Y., Sakurai, T., Haga, H., Hirota, S., Ikeuchi, H., Nakase, H., Marusawa, H., Chiba, T., Takeuchi, O., Miyano, S., Seno, H., Ogawa, S.: Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis. Nature, 577: 260-265 (2020).
    4. Kanamori, T., Sanada, M., Ri, M., Ueno, H., Nishijima, D., Yasuda, T., Tachita, T., Narita, T., Kusumoto, S., Inagaki, A., Ishihara, R., Murakami, Y., Kobayashi, N., Shiozawa, Y., Yoshida K., Nakagawa, M. M., Nannya, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Horibe, K., Handa, H., Ogawa, S., Iida, S.: Genomic analysis of multiple myeloma using targeted capture sequencing in the Japanese cohort. Br J Haematol, 191: 755-763 (2020).
    5. Kimura, S., Seki, M., Kawai, T., Goto, H., Yoshida K., Isobe, T., Sekiguchi, M., Watanabe, K., Kubota, Y., Nannya, Y., Ueno, H., Shiozawa, Y., Suzuki, H., Shiraishi, Y., Ohki, K., Kato, M., Koh, K., Kobayashi, R., Deguchi, T., Hashii, Y., Imamura, T., Sato, A., Kiyokawa, N., Manabe, A., Sanada, M., Mansour, M. R., Ohara, A., Horibe, K., Kobayashi, M., Oka, A., Hayashi, Y., Miyano, S., Hata, K., Ogawa, S., Takita, J.: DNA methylation-based classification reveals difference between pediatric T-cell acute lymphoblastic leukemia and normal thymocytes. Leukemia, 34: 1163-1168 (2020).
    6. Kubota, Y., Seki, M., Kawai, T., Isobe, T., Yoshida, M., Sekiguchi, M., Kimura, S., Watanabe, K., Sato-Otsubo, A., Yoshida K., Suzuki, H., Kataoka, K., Fujii, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Hiwatari, M., Oka, A., Hayashi, Y., Miyano, S., Ogawa, S., Hata, K., Tanaka, Y., Takita, J.: Comprehensive genetic analysis of pediatric germ cell tumors identifies potential drug targets. Commun Biol, 3: 544 (2020).
    7. Matsuo, H., Yoshida K., Nakatani, K., Harata, Y., Higashitani, M., Ito, Y., Kamikubo, Y., Shiozawa, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Okada, A., Nannya, Y., Takeda, J., Ueno, H., Kiyokawa, N., Tomizawa, D., Taga, T., Tawa, A., Miyano, S., Meggendorfer, M., Haferlach, C., Ogawa, S., Adachi, S.: Fusion partner-specific mutation profiles and KRAS mutations as adverse prognostic factors in MLL-rearranged AML. Blood Adv, 4: 4623-4631 (2020).
    8. Mylonas, E., Yoshida K., Frick, M., Hoyer, K., Christen, F., Kaeda, J., Obenaus, M., Noerenberg, D., Hennch, C., Chan, W., Ochi, Y., Shiraishi, Y., Shiozawa, Y., Zenz, T., Oakes, C. C., Sawitzki, B., Schwarz, M., Bullinger, L., le Coutre, P., Rose-Zerilli, M. J. J., Ogawa, S., Damm, F.: Single-cell analysis based dissection of clonality in myelofibrosis. Nat Commun, 11: 73 (2020).
    9. Ochi, Y., Kon, A., Sakata, T., Nakagawa, M. M., Nakazawa, N., Kakuta, M., Kataoka, K., Koseki, H., Nakayama, M., Morishita, D., Tsuruyama, T., Saiki, R., Yoda, A., Okuda, R., Yoshizato, T., Yoshida K., Shiozawa, Y., Nannya, Y., Kotani, S., Kogure, Y., Kakiuchi, N., Nishimura, T., Makishima, H., Malcovati, L., Yokoyama, A., Takeuchi, K., Sugihara, E., Sato, T. A., Sanada, M., Takaori-Kondo, A., Cazzola, M., Kengaku, M., Miyano, S., Shirahige, K., Suzuki, H. I., Ogawa, S.: Combined Cohesin-RUNX1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes. Cancer Discov, 10: 836-853 (2020).
    10. Ogura, H., Ohga, S., Aoki, T., Utsugisawa, T., Takahashi, H., Iwai, A., Watanabe, K., Okuno, Y., Yoshida K., Ogawa, S., Miyano, S., Kojima, S., Yamamoto, T., Yamamoto-Shimojima, K., Kanno, H.: Novel COL4A1 mutations identified in infants with congenital hemolytic anemia in association with brain malformations. Hum Genome Var, 7: 42 (2020).
    11. Polprasert, C., Takeda, J., Niparuck, P., Rattanathammethee, T., Pirunsarn, A., Suksusut, A., Kobbuaklee, S., Wudhikarn, K., Lawasut, P., Kongkiatkamon, S., Chuncharunee, S., Songserm, K., Phowthongkum, P., Bunworasate, U., Nannya, Y., Yoshida K., Makishima, H., Ogawa, S., Rojnuckarin, P.: Novel DDX41 variants in Thai patients with myeloid neoplasms. Int J Hematol, 111: 241-246 (2020).
    12. Sekiguchi, M., Seki, M., Kawai, T., Yoshida K., Yoshida, M., Isobe, T., Hoshino, N., Shirai, R., Tanaka, M., Souzaki, R., Watanabe, K., Arakawa, Y., Nannya, Y., Suzuki, H., Fujii, Y., Kataoka, K., Shiraishi, Y., Chiba, K., Tanaka, H., Shimamura, T., Sato, Y., Sato-Otsubo, A., Kimura, S., Kubota, Y., Hiwatari, M., Koh, K., Hayashi, Y., Kanamori, Y., Kasahara, M., Kohashi, K., Kato, M., Yoshioka, T., Matsumoto, K., Oka, A., Taguchi, T., Sanada, M., Tanaka, Y., Miyano, S., Hata, K., Ogawa, S., Takita, J.: Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets. NPJ Precis Oncol, 4: 20 (2020).
    13. Ueno, H., Yoshida K., Shiozawa, Y., Nannya, Y., Iijima-Yamashita, Y., Kiyokawa, N., Shiraishi, Y., Chiba, K., Tanaka, H., Isobe, T., Seki, M., Kimura, S., Makishima, H., Nakagawa, M. M., Kakiuchi, N., Kataoka, K., Yoshizato, T., Nishijima, D., Deguchi, T., Ohki, K., Sato, A., Takahashi, H., Hashii, Y., Tokimasa, S., Hara, J., Kosaka, Y., Kato, K., Inukai, T., Takita, J., Imamura, T., Miyano, S., Manabe, A., Horibe, K., Ogawa, S., Sanada, M.: Landscape of driver mutations and their clinical impacts in pediatric B-cell precursor acute lymphoblastic leukemia. Blood Adv, 4: 5165-5173 (2020).
    14. Yasuda, T., Sanada, M., Nishijima, D., Kanamori, T., Iijima, Y., Hattori, H., Saito, A., Miyoshi, H., Ishikawa, Y., Asou, N., Usuki, K., Hirabayashi, S., Kato, M., Ri, M., Handa, H., Ishida, T., Shibayama, H., Abe, M., Iriyama, C., Karube, K., Nishikori, M., Ohshima, K., Kataoka, K., Yoshida K., Shiraishi, Y., Goto, H., Adachi, S., Kobayashi, R., Kiyoi, H., Miyazaki, Y., Ogawa, S., Kurahashi, H., Yokoyama, H., Manabe, A., Iida, S., Tomita, A., Horibe, K.: Clinical utility of target capture-based panel sequencing in hematological malignancies: A multicenter feasibility study. Cancer Sci, 111: 3367-3378 (2020).
    15. Yoshida K., Gowers, K. H. C., Lee-Six, H., Chandrasekharan, D. P., Coorens, T., Maughan, E. F., Beal, K., Menzies, A., Millar, F. R., Anderson, E., Clarke, S. E., Pennycuick, A., Thakrar, R. M., Butler, C. R., Kakiuchi, N., Hirano, T., Hynds, R. E., Stratton, M. R., Martincorena, I., Janes, S. M., Campbell, P. J.: Tobacco smoking and somatic mutations in human bronchial epithelium. Nature, 578: 266-272 (2020).

2019年

    1. Berger, G., Gerritsen, M., Yi, G., Koorenhof-Scheele, T. N., Kroeze, L. I., Stevens-Kroef, M., Yoshida K., Shiraishi, Y., van den Berg, E., Schepers, H., Huls, G., Mulder, A. B., Ogawa, S., Martens, J. H. A., Jansen, J. H., Vellenga, E.: Ring sideroblasts in AML are associated with adverse risk characteristics and have a distinct gene expression pattern. Blood Adv, 3: 3111-3122 (2019).
    2. Christen, F., Hoyer, K., Yoshida K., Hou, H. A., Waldhueter, N., Heuser, M., Hills, R. K., Chan, W., Hablesreiter, R., Blau, O., Ochi, Y., Klement, P., Chou, W. C., Blau, I. W., Tang, J. L., Zemojtel, T., Shiraishi, Y., Shiozawa, Y., Thol, F., Ganser, A., Lowenberg, B., Linch, D. C., Bullinger, L., Valk, P. J. M., Tien, H. F., Gale, R. E., Ogawa, S., Damm, F.: Genomic landscape and clonal evolution of acute myeloid leukemia with t(8;21): an international study on 331 patients. Blood, 133: 1140-1151 (2019).
    3. Frick, M., Chan, W., Arends, C. M., Hablesreiter, R., Halik, A., Heuser, M., Michonneau, D., Blau, O., Hoyer, K., Christen, F., Galan-Sousa, J., Noerenberg, D., Wais, V., Stadler, M., Yoshida K., Schetelig, J., Schuler, E., Thol, F., Clappier, E., Christopeit, M., Ayuk, F., Bornhauser, M., Blau, I. W., Ogawa, S., Zemojtel, T., Gerbitz, A., Wagner, E. M., Spriewald, B. M., Schrezenmeier, H., Kuchenbauer, F., Kobbe, G., Wiesneth, M., Koldehoff, M., Socie, G., Kroeger, N., Bullinger, L., Thiede, C., Damm, F.: Role of Donor Clonal Hematopoiesis in Allogeneic Hematopoietic Stem-Cell Transplantation. J Clin Oncol, 37: 375-385 (2019).
    4. Haase, D., Stevenson, K. E., Neuberg, D., Maciejewski, J. P., Nazha, A., Sekeres, M. A., Ebert, B. L., Garcia-Manero, G., Haferlach, C., Haferlach, T., Kern, W., Ogawa, S., Nagata, Y., Yoshida K., Graubert, T. A., Walter, M. J., List, A. F., Komrokji, R. S., Padron, E., Sallman, D., Papaemmanuil, E., Campbell, P. J., Savona, M. R., Seegmiller, A., Ades, L., Fenaux, P., Shih, L. Y., Bowen, D., Groves, M. J., Tauro, S., Fontenay, M., Kosmider, O., Bar-Natan, M., Steensma, D., Stone, R., Heuser, M., Thol, F., Cazzola, M., Malcovati, L., Karsan, A., Ganster, C., Hellstrom-Lindberg, E., Boultwood, J., Pellagatti, A., Santini, V., Quek, L., Vyas, P., Tuchler, H., Greenberg, P. L., Bejar, R., International Working Group for, M. D. S. M. P. C.: TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups. Leukemia, 33: 1747-1758 (2019).
    5. Hoshino, A., Yang, X., Tanita, K., Yoshida K., Ono, T., Nishida, N., Okuno, Y., Kanzaki, T., Goi, K., Fujino, H., Ohshima, K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Ogawa, S., Kojima, S., Morio, T., Kanegane, H.: Modification of cellular and humoral immunity by somatically reverted T cells in X-linked lymphoproliferative syndrome type 1. J Allergy Clin Immunol, 143: 421-424 e411 (2019).
    6. Kataoka, K., Miyoshi, H., Sakata, S., Dobashi, A., Couronne, L., Kogure, Y., Sato, Y., Nishida, K., Gion, Y., Shiraishi, Y., Tanaka, H., Chiba, K., Watatani, Y., Kakiuchi, N., Shiozawa, Y., Yoshizato, T., Yoshida K., Makishima, H., Sanada, M., Onozawa, M., Teshima, T., Yoshiki, Y., Ishida, T., Suzuki, K., Shimada, K., Tomita, A., Kato, M., Ota, Y., Izutsu, K., Demachi-Okamura, A., Akatsuka, Y., Miyano, S., Yoshino, T., Gaulard, P., Hermine, O., Takeuchi, K., Ohshima, K., Ogawa, S.: Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas. Leukemia, 33: 1687-1699 (2019).
    7. Kim, S. K., Takeda, H., Takai, A., Matsumoto, T., Kakiuchi, N., Yokoyama, A., Yoshida K., Kaido, T., Uemoto, S., Minamiguchi, S., Haga, H., Shiraishi, Y., Miyano, S., Seno, H., Ogawa, S., Marusawa, H.: Comprehensive analysis of genetic aberrations linked to tumorigenesis in regenerative nodules of liver cirrhosis. J Gastroenterol, 54: 628-640 (2019).
    8. Kimura, S., Seki, M., Yoshida K., Shiraishi, Y., Akiyama, M., Koh, K., Imamura, T., Manabe, A., Hayashi, Y., Kobayashi, M., Oka, A., Miyano, S., Ogawa, S., Takita, J.: NOTCH1 pathway activating mutations and clonal evolution in pediatric T-cell acute lymphoblastic leukemia. Cancer Sci, 110: 784-794 (2019).
    9. Kobayashi, K., Mizuta, S., Yamane, N., Ueno, H., Yoshida K., Kato, I., Umeda, K., Hiramatsu, H., Suehiro, M., Maihara, T., Usami, I., Shiraishi, Y., Chiba, K., Miyano, S., Adachi, S., Ogawa, S., Kiyokawa, N., Heike, T.: Paraneoplastic hypereosinophilic syndrome associated with IL3-IgH positive acute lymphoblastic leukemia. Pediatr Blood Cancer, 66: e27449 (2019).
    10. Kohara, H., Utsugisawa, T., Sakamoto, C., Hirose, L., Ogawa, Y., Ogura, H., Sugawara, A., Liao, J., Aoki, T., Iwasaki, T., Asai, T., Doisaki, S., Okuno, Y., Muramatsu, H., Abe, T., Kurita, R., Miyamoto, S., Sakuma, T., Shiba, M., Yamamoto, T., Ohga, S., Yoshida K., Ogawa, S., Ito, E., Kojima, S., Kanno, H., Tani, K.: KLF1 mutation E325K induces cell cycle arrest in erythroid cells differentiated from congenital dyserythropoietic anemia patient-specific induced pluripotent stem cells. Exp Hematol, 73: 25-37 e28 (2019).
    11. Kotani, S., Yoda, A., Kon, A., Kataoka, K., Ochi, Y., Shiozawa, Y., Hirsch, C., Takeda, J., Ueno, H., Yoshizato, T., Yoshida K., Nakagawa, M. M., Nannya, Y., Kakiuchi, N., Yamauchi, T., Aoki, K., Shiraishi, Y., Miyano, S., Maeda, T., Maciejewski, J. P., Takaori-Kondo, A., Ogawa, S., Makishima, H.: Molecular pathogenesis of disease progression in MLL-rearranged AML. Leukemia, 33: 612-624 (2019).
    12. Kubota, Y., Uryu, K., Ito, T., Seki, M., Kawai, T., Isobe, T., Kumagai, T., Toki, T., Yoshida K., Suzuki, H., Kataoka, K., Shiraishi, Y., Chiba, K., Tanaka, H., Ohki, K., Kiyokawa, N., Kagawa, J., Miyano, S., Oka, A., Hayashi, Y., Ogawa, S., Terui, K., Sato, A., Hata, K., Ito, E., Takita, J.: Integrated genetic and epigenetic analysis revealed heterogeneity of acute lymphoblastic leukemia in Down syndrome. Cancer Sci, 110: 3358-3367 (2019).
    13. Mori, M., Hira, A., Yoshida K., Muramatsu, H., Okuno, Y., Shiraishi, Y., Anmae, M., Yasuda, J., Tadaka, S., Kinoshita, K., Osumi, T., Noguchi, Y., Adachi, S., Kobayashi, R., Kawabata, H., Imai, K., Morio, T., Tamura, K., Takaori-Kondo, A., Yamamoto, M., Miyano, S., Kojima, S., Ito, E., Ogawa, S., Matsuo, K., Yabe, H., Yabe, M., Takata, M.: Pathogenic mutations identified by a multimodality approach in 117 Japanese Fanconi anemia patients. Haematologica, 104: 1962-1973 (2019).
    14. Nagao, Y., Mimura, N., Takeda, J., Yoshida K., Shiozawa, Y., Oshima, M., Aoyama, K., Saraya, A., Koide, S., Rizq, O., Hasegawa, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Nishijima, D., Isshiki, Y., Kayamori, K., Kawajiri-Manako, C., Oshima-Hasegawa, N., Tsukamoto, S., Mitsukawa, S., Takeda, Y., Ohwada, C., Takeuchi, M., Iseki, T., Misawa, S., Miyano, S., Ohara, O., Yokote, K., Sakaida, E., Kuwabara, S., Sanada, M., Iwama, A., Ogawa, S., Nakaseko, C.: Genetic and transcriptional landscape of plasma cells in POEMS syndrome. Leukemia, 33: 1723-1735 (2019).
    15. Nagata, Y., Makishima, H., Kerr, C. M., Przychodzen, B. P., Aly, M., Goyal, A., Awada, H., Asad, M. F., Kuzmanovic, T., Suzuki, H., Yoshizato, T., Yoshida K., Chiba, K., Tanaka, H., Shiraishi, Y., Miyano, S., Mukherjee, S., LaFramboise, T., Nazha, A., Sekeres, M. A., Radivoyevitch, T., Haferlach, T., Ogawa, S., Maciejewski, J. P.: Invariant patterns of clonal succession determine specific clinical features of myelodysplastic syndromes. Nat Commun, 10: 5386 (2019).
    16. Okano, T., Imai, K., Tsujita, Y., Mitsuiki, N., Yoshida K., Kamae, C., Honma, K., Mitsui-Sekinaka, K., Sekinaka, Y., Kato, T., Hanabusa, K., Endo, E., Takashima, T., Hiroki, H., Yeh, T. W., Tanaka, K., Nagahori, M., Tsuge, I., Bando, Y., Iwasaki, F., Shikama, Y., Inoue, M., Kimoto, T., Moriguchi, N., Yuza, Y., Kaneko, T., Suzuki, K., Matsubara, T., Maruo, Y., Kunitsu, T., Waragai, T., Sano, H., Hashimoto, Y., Tasaki, K., Suzuki, O., Shirakawa, T., Kato, M., Uchiyama, T., Ishimura, M., Tauchi, T., Yagasaki, H., Jou, S. T., Yu, H. H., Kanegane, H., Kracker, S., Durandy, A., Kojima, D., Muramatsu, H., Wada, T., Inoue, Y., Takada, H., Kojima, S., Ogawa, S., Ohara, O., Nonoyama, S., Morio, T.: Hematopoietic stem cell transplantation for progressive combined immunodeficiency and lymphoproliferation in patients with activated phosphatidylinositol-3-OH kinase delta syndrome type 1. J Allergy Clin Immunol, 143: 266-275 (2019).
    17. Okuno, Y., Murata, T., Sato, Y., Muramatsu, H., Ito, Y., Watanabe, T., Okuno, T., Murakami, N., Yoshida K., Sawada, A., Inoue, M., Kawa, K., Seto, M., Ohshima, K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Narita, Y., Yoshida, M., Goshima, F., Kawada, J. I., Nishida, T., Kiyoi, H., Kato, S., Nakamura, S., Morishima, S., Yoshikawa, T., Fujiwara, S., Shimizu, N., Isobe, Y., Noguchi, M., Kikuta, A., Iwatsuki, K., Takahashi, Y., Kojima, S., Ogawa, S., Kimura, H.: Defective Epstein-Barr virus in chronic active infection and haematological malignancy. Nat Microbiol, 4: 404-413 (2019).
    18. Ono, S., Matsuda, J., Watanabe, E., Akaike, H., Teranishi, H., Miyata, I., Otomo, T., Sadahira, Y., Mizuochi, T., Kusano, H., Kage, M., Ueno, H., Yoshida K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Ogawa, S., Hayashi, Y., Kanegane, H., Ouchi, K.: Novel neuroblastoma amplified sequence (NBAS) mutations in a Japanese boy with fever-triggered recurrent acute liver failure. Hum Genome Var, 6: 2 (2019).
    19. Polprasert, C., Takeuchi, Y., Kakiuchi, N., Yoshida K., Assanasen, T., Sitthi, W., Bunworasate, U., Pirunsarn, A., Wudhikarn, K., Lawasut, P., Uaprasert, N., Kongkiatkamon, S., Moonla, C., Sanada, M., Akita, N., Takeda, J., Fujii, Y., Suzuki, H., Nannya, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Rojnuckarin, P., Ogawa, S., Makishima, H.: Frequent germline mutations of HAVCR2 in sporadic subcutaneous panniculitis-like T-cell lymphoma. Blood Adv, 3: 588-595 (2019).
    20. Shiba, N., Yoshida K., Hara, Y., Yamato, G., Shiraishi, Y., Matsuo, H., Okuno, Y., Chiba, K., Tanaka, H., Kaburagi, T., Takeuchi, M., Ohki, K., Sanada, M., Okubo, J., Tomizawa, D., Taki, T., Shimada, A., Sotomatsu, M., Horibe, K., Taga, T., Adachi, S., Tawa, A., Miyano, S., Ogawa, S., Hayashi, Y.: Transcriptome analysis offers a comprehensive illustration of the genetic background of pediatric acute myeloid leukemia. Blood Adv, 3: 3157-3169 (2019).
    21. Takashima, Y., Kawaguchi, A., Sato, R., Yoshida K., Hayano, A., Homma, J., Fukai, J., Iwadate, Y., Kajiwara, K., Ishizawa, S., Hondoh, H., Nakano, M., Ogawa, S., Tashiro, K., Yamanaka, R.: Differential expression of individual transcript variants of PD-1 and PD-L2 genes on Th-1/Th-2 status is guaranteed for prognosis prediction in PCNSL. Sci Rep, 9: 10004 (2019).
    22. Watatani, Y., Sato, Y., Miyoshi, H., Sakamoto, K., Nishida, K., Gion, Y., Nagata, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Zhao, L., Ochi, Y., Takeuchi, Y., Takeda, J., Ueno, H., Kogure, Y., Shiozawa, Y., Kakiuchi, N., Yoshizato, T., Nakagawa, M. M., Nanya, Y., Yoshida K., Makishima, H., Sanada, M., Sakata-Yanagimoto, M., Chiba, S., Matsuoka, R., Noguchi, M., Hiramoto, N., Ishikawa, T., Kitagawa, J., Nakamura, N., Tsurumi, H., Miyazaki, T., Kito, Y., Miyano, S., Shimoda, K., Takeuchi, K., Ohshima, K., Yoshino, T., Ogawa, S., Kataoka, K.: Molecular heterogeneity in peripheral T-cell lymphoma, not otherwise specified revealed by comprehensive genetic profiling. Leukemia, 33: 2867-2883 (2019).
    23. Yabe, M., Koike, T., Ohtsubo, K., Imai, E., Morimoto, T., Takakura, H., Koh, K., Yoshida K., Ogawa, S., Ito, E., Okuno, Y., Muramatsu, H., Kojima, S., Matsuo, K., Mori, M., Hira, A., Takata, M., Yabe, H.: Associations of complementation group, ALDH2 genotype, and clonal abnormalities with hematological outcome in Japanese patients with Fanconi anemia. Ann Hematol, 98: 271-280 (2019).
    24. Yokoyama, A., Kakiuchi, N., Yoshizato, T., Nannya, Y., Suzuki, H., Takeuchi, Y., Shiozawa, Y., Sato, Y., Aoki, K., Kim, S. K., Fujii, Y., Yoshida K., Kataoka, K., Nakagawa, M. M., Inoue, Y., Hirano, T., Shiraishi, Y., Chiba, K., Tanaka, H., Sanada, M., Nishikawa, Y., Amanuma, Y., Ohashi, S., Aoyama, I., Horimatsu, T., Miyamoto, S., Tsunoda, S., Sakai, Y., Narahara, M., Brown, J. B., Sato, Y., Sawada, G., Mimori, K., Minamiguchi, S., Haga, H., Seno, H., Miyano, S., Makishima, H., Muto, M., Ogawa, S.: Age-related remodelling of oesophageal epithelia by mutated cancer drivers. Nature, 565: 312-317 (2019).
    25. Labuhn, M., Perkins, K., Matzk, S., Varghese, L., Garnett, C., Papaemmanuil, E., Metzner, M., Kennedy, A., Amstislavskiy, V., Risch, T., Bhayadia, R., Samulowski, D., Hernandez, DC., Stoilova, B., Iotchkova, V., Oppermann, U., Scheer, C., Yoshida, K., Schwarzer, A., Taub, JW., Crispino, JD., Weiss, MJ., Hayashi, Y., Taga, T., Ito, E., Ogawa, S., Reinhardt, D., Yaspo, ML., Campbell, PJ., Roberts, I., Constantinescu, SN., Vyas, P., Heckl, D., Klusmann, JH.: Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome. Cancer Cell, 36: 123-138 (2019)

2018年

    1. Arends, C. M., Galan-Sousa, J., Hoyer, K., Chan, W., Jager, M., Yoshida K., Seemann, R., Noerenberg, D., Waldhueter, N., Fleischer-Notter, H., Christen, F., Schmitt, C. A., Dorken, B., Pelzer, U., Sinn, M., Zemojtel, T., Ogawa, S., Mardian, S., Schreiber, A., Kunitz, A., Kruger, U., Bullinger, L., Mylonas, E., Frick, M., Damm, F.: Hematopoietic lineage distribution and evolutionary dynamics of clonal hematopoiesis. Leukemia, 32: 1908-1919 (2018).
    2. Berger, G., Kroeze, L. I., Koorenhof-Scheele, T. N., de Graaf, A. O., Yoshida K., Ueno, H., Shiraishi, Y., Miyano, S., van den Berg, E., Schepers, H., van der Reijden, B. A., Ogawa, S., Vellenga, E., Jansen, J. H.: Early detection and evolution of preleukemic clones in therapy-related myeloid neoplasms following autologous SCT. Blood, 131: 1846-1857 (2018).
    3. Cardinez, C., Miraghazadeh, B., Tanita, K., da Silva, E., Hoshino, A., Okada, S., Chand, R., Asano, T., Tsumura, M., Yoshida K., Ohnishi, H., Kato, Z., Yamazaki, M., Okuno, Y., Miyano, S., Kojima, S., Ogawa, S., Andrews, T. D., Field, M. A., Burgio, G., Morio, T., Vinuesa, C. G., Kanegane, H., Cook, M. C.: Gain-of-function IKBKB mutation causes human combined immune deficiency. J Exp Med, 215: 2715-2724 (2018).
    4. Fujisawa, M., Sakata-Yanagimoto, M., Nishizawa, S., Komori, D., Gershon, P., Kiryu, M., Tanzima, S., Fukumoto, K., Enami, T., Muratani, M., Yoshida K., Ogawa, S., Matsue, K., Nakamura, N., Takeuchi, K., Izutsu, K., Fujimoto, K., Teshima, T., Miyoshi, H., Gaulard, P., Ohshima, K., Chiba, S.: Activation of RHOA-VAV1 signaling in angioimmunoblastic T-cell lymphoma. Leukemia, 32: 694-702 (2018).
    5. Hamada, M., Doisaki, S., Okuno, Y., Muramatsu, H., Hama, A., Kawashima, N., Narita, A., Nishio, N., Yoshida K., Kanno, H., Manabe, A., Taga, T., Takahashi, Y., Miyano, S., Ogawa, S., Kojima, S.: Whole-exome analysis to detect congenital hemolytic anemia mimicking congenital dyserythropoietic anemia. Int J Hematol, 108: 306-311 (2018).
    6. Hiramoto, N., Takeda, J., Yoshida K., Ono, Y., Yoshioka, S., Yamauchi, N., Fujimoto, A., Maruoka, H., Shiraishi, Y., Tanaka, H., Chiba, K., Imai, Y., Miyano, S., Ogawa, S., Ishikawa, T.: Donor cell-derived transient abnormal myelopoiesis as a specific complication of umbilical cord blood transplantation. Bone Marrow Transplant, 53: 225-227 (2018).
    7. Hoshino, A., Takashima, T., Yoshida K., Morimoto, A., Kawahara, Y., Yeh, T. W., Okano, T., Yamashita, M., Mitsuiki, N., Imai, K., Sakatani, T., Nakazawa, A., Okuno, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Ogawa, S., Kojima, S., Morio, T., Kanegane, H.: Dysregulation of Epstein-Barr Virus Infection in Hypomorphic ZAP70 Mutation. J Infect Dis, 218: 825-834 (2018).
    8. Isobe, T., Seki, M., Yoshida K., Sekiguchi, M., Shiozawa, Y., Shiraishi, Y., Kimura, S., Yoshida, M., Inoue, Y., Yokoyama, A., Kakiuchi, N., Suzuki, H., Kataoka, K., Sato, Y., Kawai, T., Chiba, K., Tanaka, H., Shimamura, T., Kato, M., Iguchi, A., Hama, A., Taguchi, T., Akiyama, M., Fujimura, J., Inoue, A., Ito, T., Deguchi, T., Kiyotani, C., Iehara, T., Hosoi, H., Oka, A., Sanada, M., Tanaka, Y., Hata, K., Miyano, S., Ogawa, S., Takita, J.: Integrated Molecular Characterization of the Lethal Pediatric Cancer Pancreatoblastoma. Cancer Res, 78: 865-876 (2018).
    9. Katagiri, S., Umezu, T., Azuma, K., Asano, M., Akahane, D., Makishima, H., Yoshida K., Watatani, Y., Chiba, K., Miyano, S., Ogawa, S., Ohyashiki, J. H., Ohyashiki, K.: Hidden FLT3-D835Y clone in FLT3-ITD-positive acute myeloid leukemia that evolved into very late relapse with T-lymphoblastic leukemia. Leuk Lymphoma, 59: 1490-1493 (2018).
    10. Kataoka, K., Iwanaga, M., Yasunaga, J. I., Nagata, Y., Kitanaka, A., Kameda, T., Yoshimitsu, M., Shiraishi, Y., Sato-Otsubo, A., Sanada, M., Chiba, K., Tanaka, H., Ochi, Y., Aoki, K., Suzuki, H., Shiozawa, Y., Yoshizato, T., Sato, Y., Yoshida K., Nosaka, K., Hishizawa, M., Itonaga, H., Imaizumi, Y., Munakata, W., Shide, K., Kubuki, Y., Hidaka, T., Nakamaki, T., Ishiyama, K., Miyawaki, S., Ishii, R., Nureki, O., Tobinai, K., Miyazaki, Y., Takaori-Kondo, A., Shibata, T., Miyano, S., Ishitsuka, K., Utsunomiya, A., Shimoda, K., Matsuoka, M., Watanabe, T., Ogawa, S.: Prognostic relevance of integrated genetic profiling in adult T-cell leukemia/lymphoma. Blood, 131: 215-225 (2018).
    11. Kon, A., Yamazaki, S., Nannya, Y., Kataoka, K., Ota, Y., Nakagawa, M. M., Yoshida K., Shiozawa, Y., Morita, M., Yoshizato, T., Sanada, M., Nakayama, M., Koseki, H., Nakauchi, H., Ogawa, S.: Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice. Blood, 131: 621-635 (2018).
    12. Kouzuki, K., Umeda, K., Saida, S., Kato, I., Hiramatsu, H., Funaki, T., Kanda, K., Muramatsu, H., Yoshida K., Ogawa, S., Adachi, S.: Sudden Intracranial Hemorrhage in a Patient With Atypical Chronic Myeloid Leukemia in Chronic Phase. J Pediatr Hematol Oncol, 40: e553-e556 (2018).
    13. Kudo, K., Ueno, H., Sato, T., Kubo, K., Kanezaki, R., Kobayashi, A., Kamio, T., Sasaki, S., Terui, K., Kurose, A., Yoshida K., Shiozawa, Y., Toki, T., Ogawa, S., Ito, E.: Two siblings with familial neuroblastoma with distinct clinical phenotypes harboring an ALK germline mutation. Genes Chromosomes Cancer, 57: 665-669 (2018).
    14. Matsuo, H., Yoshida K., Fukumura, K., Nakatani, K., Noguchi, Y., Takasaki, S., Noura, M., Shiozawa, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Okada, A., Nannya, Y., Takeda, J., Ueno, H., Shiba, N., Yamato, G., Handa, H., Ono, Y., Hiramoto, N., Ishikawa, T., Usuki, K., Ishiyama, K., Miyawaki, S., Itonaga, H., Miyazaki, Y., Kawamura, M., Yamaguchi, H., Kiyokawa, N., Tomizawa, D., Taga, T., Tawa, A., Hayashi, Y., Mano, H., Miyano, S., Kamikubo, Y., Ogawa, S., Adachi, S.: Recurrent CCND3 mutations in MLL-rearranged acute myeloid leukemia. Blood Adv, 2: 2879-2889 (2018).
    15. Murakami, N., Okuno, Y., Yoshida K., Shiraishi, Y., Nagae, G., Suzuki, K., Narita, A., Sakaguchi, H., Kawashima, N., Wang, X., Xu, Y., Chiba, K., Tanaka, H., Hama, A., Sanada, M., Ito, M., Hirayama, M., Watanabe, A., Ueno, T., Kojima, S., Aburatani, H., Mano, H., Miyano, S., Ogawa, S., Takahashi, Y., Muramatsu, H.: Integrated molecular profiling of juvenile myelomonocytic leukemia. Blood, 131: 1576-1586 (2018).
    16. Nagata, Y., Narumi, S., Guan, Y., Przychodzen, B. P., Hirsch, C. M., Makishima, H., Shima, H., Aly, M., Pastor, V., Kuzmanovic, T., Radivoyevitch, T., Adema, V., Awada, H., Yoshida K., Li, S., Sole, F., Hanna, R., Jha, B. K., LaFramboise, T., Ogawa, S., Sekeres, M. A., Wlodarski, M. W., Cammenga, J., Maciejewski, J. P.: Germline loss-of-function SAMD9 and SAMD9L alterations in adult myelodysplastic syndromes. Blood, 132: 2309-2313 (2018).
    17. Ochi, Y., Hiramoto, N., Yoshizato, T., Ono, Y., Takeda, J., Shiozawa, Y., Yoshida K., Kakiuchi, N., Shiraishi, Y., Tanaka, H., Chiba, K., Kazuma, Y., Tabata, S., Yonetani, N., Uehara, K., Yamashita, D., Imai, Y., Nagafuji, K., Yamakawa, M., Miyano, S., Takaori-Kondo, A., Ogawa, S., Ishikawa, T.: Clonally related diffuse large B-cell lymphoma and interdigitating dendritic cell sarcoma sharing MYC translocation. Haematologica, 103: e553-e556 (2018).
    18. Sakai, H., Hosono, N., Nakazawa, H., Przychodzen, B., Polprasert, C., Carraway, H. E., Sekeres, M. A., Radivoyevitch, T., Yoshida K., Sanada, M., Yoshizato, T., Kataoka, K., Nakagawa, M. M., Ueno, H., Nannya, Y., Kon, A., Shiozawa, Y., Takeda, J., Shiraishi, Y., Chiba, K., Miyano, S., Singh, J., Padgett, R. A., Ogawa, S., Maciejewski, J. P., Makishima, H.: A novel genetic and morphologic phenotype of ARID2-mediated myelodysplasia. Leukemia, 32: 839-843 (2018).
    19. Shiozawa, Y., Malcovati, L., Galli, A., Sato-Otsubo, A., Kataoka, K., Sato, Y., Watatani, Y., Suzuki, H., Yoshizato, T., Yoshida K., Sanada, M., Makishima, H., Shiraishi, Y., Chiba, K., Hellstrom-Lindberg, E., Miyano, S., Ogawa, S., Cazzola, M.: Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia. Nat Commun, 9: 3649 (2018).
    20. Takagi, M., Hoshino, A., Yoshida K., Ueno, H., Imai, K., Piao, J., Kanegane, H., Yamashita, M., Okano, T., Muramatsu, H., Okuno, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Ogawa, S., Hayashi, Y., Kojima, S., Morio, T.: Genetic heterogeneity of uncharacterized childhood autoimmune diseases with lymphoproliferation. Pediatr Blood Cancer, 65:  (2018).
    21. Toki, T., Yoshida K., Wang, R., Nakamura, S., Maekawa, T., Goi, K., Katoh, M. C., Mizuno, S., Sugiyama, F., Kanezaki, R., Uechi, T., Nakajima, Y., Sato, Y., Okuno, Y., Sato-Otsubo, A., Shiozawa, Y., Kataoka, K., Shiraishi, Y., Sanada, M., Chiba, K., Tanaka, H., Terui, K., Sato, T., Kamio, T., Sakaguchi, H., Ohga, S., Kuramitsu, M., Hamaguchi, I., Ohara, A., Kanno, H., Miyano, S., Kojima, S., Ishiguro, A., Sugita, K., Kenmochi, N., Takahashi, S., Eto, K., Ogawa, S., Ito, E.: De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome. Am J Hum Genet, 103: 440-447 (2018).
    22. Yamato, G., Shiba, N., Yoshida K., Hara, Y., Shiraishi, Y., Ohki, K., Okubo, J., Park, M. J., Sotomatsu, M., Arakawa, H., Kiyokawa, N., Tomizawa, D., Adachi, S., Taga, T., Horibe, K., Miyano, S., Ogawa, S., Hayashi, Y.: RUNX1 mutations in pediatric acute myeloid leukemia are associated with distinct genetic features and an inferior prognosis. Blood, 131: 2266-2270 (2018).

2017年

    1. da Silva-Coelho, P., Kroeze, L. I., Yoshida K., Koorenhof-Scheele, T. N., Knops, R., van de Locht, L. T., de Graaf, A. O., Massop, M., Sandmann, S., Dugas, M., Stevens-Kroef, M. J., Cermak, J., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., de Witte, T., Blijlevens, N. M. A., Muus, P., Huls, G., van der Reijden, B. A., Ogawa, S., Jansen, J. H.: Clonal evolution in myelodysplastic syndromes. Nat Commun, 8: 15099 (2017).
    2. Hirabayashi, S., Seki, M., Hasegawa, D., Kato, M., Hyakuna, N., Shuo, T., Kimura, S., Yoshida K., Kataoka, K., Fujii, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Kiyokawa, N., Miyano, S., Ogawa, S., Takita, J., Manabe, A.: Constitutional abnormalities of IDH1 combined with secondary mutations predispose a patient with Maffucci syndrome to acute lymphoblastic leukemia. Pediatr Blood Cancer, 64:  (2017).
    3. Hiwatari, M., Seki, M., Akahoshi, S., Yoshida K., Miyano, S., Shiraishi, Y., Tanaka, H., Chiba, K., Ogawa, S., Takita, J.: Molecular studies reveal MLL-MLLT10/AF10 and ARID5B-MLL gene fusions displaced in a case of infantile acute lymphoblastic leukemia with complex karyotype. Oncol Lett, 14: 2295-2299 (2017).
    4. Hoshino, A., Okada, S., Yoshida K., Nishida, N., Okuno, Y., Ueno, H., Yamashita, M., Okano, T., Tsumura, M., Nishimura, S., Sakata, S., Kobayashi, M., Nakamura, H., Kamizono, J., Mitsui-Sekinaka, K., Ichimura, T., Ohga, S., Nakazawa, Y., Takagi, M., Imai, K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Ogawa, S., Kojima, S., Nonoyama, S., Morio, T., Kanegane, H.: Abnormal hematopoiesis and autoimmunity in human subjects with germline IKZF1 mutations. J Allergy Clin Immunol, 140: 223-231 (2017).
    5. Hosono, N., Makishima, H., Mahfouz, R., Przychodzen, B., Yoshida K., Jerez, A., LaFramboise, T., Polprasert, C., Clemente, M. J., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Sanada, M., Cui, E., Verma, A. K., McDevitt, M. A., List, A. F., Saunthararajah, Y., Sekeres, M. A., Boultwood, J., Ogawa, S., Maciejewski, J. P.: Recurrent genetic defects on chromosome 5q in myeloid neoplasms. Oncotarget, 8: 6483-6495 (2017).
    6. Ichimura, T., Yoshida K., Okuno, Y., Yujiri, T., Nagai, K., Nishi, M., Shiraishi, Y., Ueno, H., Toki, T., Chiba, K., Tanaka, H., Muramatsu, H., Hara, T., Kanno, H., Kojima, S., Miyano, S., Ito, E., Ogawa, S., Ohga, S.: Diagnostic challenge of Diamond-Blackfan anemia in mothers and children by whole-exome sequencing. Int J Hematol, 105: 515-520 (2017).
    7. Ikeda, F., Yoshida K., Toki, T., Uechi, T., Ishida, S., Nakajima, Y., Sasahara, Y., Okuno, Y., Kanezaki, R., Terui, K., Kamio, T., Kobayashi, A., Fujita, T., Sato-Otsubo, A., Shiraishi, Y., Tanaka, H., Chiba, K., Muramatsu, H., Kanno, H., Ohga, S., Ohara, A., Kojima, S., Kenmochi, N., Miyano, S., Ogawa, S., Ito, E.: Exome sequencing identified RPS15A as a novel causative gene for Diamond-Blackfan anemia. Haematologica, 102: e93-e96 (2017).
    8. Kato, I., Nishinaka, Y., Nakamura, M., Akarca, A. U., Niwa, A., Ozawa, H., Yoshida K., Mori, M., Wang, D., Morita, M., Ueno, H., Shiozawa, Y., Shiraishi, Y., Miyano, S., Gupta, R., Umeda, K., Watanabe, K., Koh, K., Adachi, S., Heike, T., Saito, M. K., Sanada, M., Ogawa, S., Marafioti, T., Watanabe, A., Nakahata, T., Enver, T.: Hypoxic adaptation of leukemic cells infiltrating the CNS affords a therapeutic strategy targeting VEGFA. Blood, 129: 3126-3129 (2017).
    9. Kato, M., Ishimaru, S., Seki, M., Yoshida K., Shiraishi, Y., Chiba, K., Kakiuchi, N., Sato, Y., Ueno, H., Tanaka, H., Inukai, T., Tomizawa, D., Hasegawa, D., Osumi, T., Arakawa, Y., Aoki, T., Okuya, M., Kaizu, K., Kato, K., Taneyama, Y., Goto, H., Taki, T., Takagi, M., Sanada, M., Koh, K., Takita, J., Miyano, S., Ogawa, S., Ohara, A., Tsuchida, M., Manabe, A.: Long-term outcome of 6-month maintenance chemotherapy for acute lymphoblastic leukemia in children. Leukemia, 31: 580-584 (2017).
    10. Makishima, H., Yoshizato, T., Yoshida K., Sekeres, M. A., Radivoyevitch, T., Suzuki, H., Przychodzen, B., Nagata, Y., Meggendorfer, M., Sanada, M., Okuno, Y., Hirsch, C., Kuzmanovic, T., Sato, Y., Sato-Otsubo, A., LaFramboise, T., Hosono, N., Shiraishi, Y., Chiba, K., Haferlach, C., Kern, W., Tanaka, H., Shiozawa, Y., Gomez-Segui, I., Husseinzadeh, H. D., Thota, S., Guinta, K. M., Dienes, B., Nakamaki, T., Miyawaki, S., Saunthararajah, Y., Chiba, S., Miyano, S., Shih, L. Y., Haferlach, T., Ogawa, S., Maciejewski, J. P.: Dynamics of clonal evolution in myelodysplastic syndromes. Nat Genet, 49: 204-212 (2017).
    11. Mandai, M., Watanabe, A., Kurimoto, Y., Hirami, Y., Morinaga, C., Daimon, T., Fujihara, M., Akimaru, H., Sakai, N., Shibata, Y., Terada, M., Nomiya, Y., Tanishima, S., Nakamura, M., Kamao, H., Sugita, S., Onishi, A., Ito, T., Fujita, K., Kawamata, S., Go, M. J., Shinohara, C., Hata, K. I., Sawada, M., Yamamoto, M., Ohta, S., Ohara, Y., Yoshida K., Kuwahara, J., Kitano, Y., Amano, N., Umekage, M., Kitaoka, F., Tanaka, A., Okada, C., Takasu, N., Ogawa, S., Yamanaka, S., Takahashi, M.: Autologous Induced Stem-Cell-Derived Retinal Cells for Macular Degeneration. N Engl J Med, 376: 1038-1046 (2017).
    12. Miyazaki, M., Miyazaki, K., Chen, K., Jin, Y., Turner, J., Moore, A. J., Saito, R., Yoshida K., Ogawa, S., Rodewald, H. R., Lin, Y. C., Kawamoto, H., Murre, C.: The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development. Immunity, 46: 818-834 e814 (2017).
    13. Monoi, A., Sugawa, M., Kato, M., Seki, M., Yoshida K., Shiraishi, Y., Sakaguchi, H., Ogawa, S., Takita, J.: Atypical dyskeratosis congenita diagnosed using whole-exome sequencing. Pediatr Int, 59: 933-935 (2017).
    14. Morita, K., Noura, M., Tokushige, C., Maeda, S., Kiyose, H., Kashiwazaki, G., Taniguchi, J., Bando, T., Yoshida K., Ozaki, T., Matsuo, H., Ogawa, S., Liu, P. P., Nakahata, T., Sugiyama, H., Adachi, S., Kamikubo, Y.: Autonomous feedback loop of RUNX1-p53-CBFB in acute myeloid leukemia cells. Sci Rep, 7: 16604 (2017).
    15. Muramatsu, H., Okuno, Y., Yoshida K., Shiraishi, Y., Doisaki, S., Narita, A., Sakaguchi, H., Kawashima, N., Wang, X., Xu, Y., Chiba, K., Tanaka, H., Hama, A., Sanada, M., Takahashi, Y., Kanno, H., Yamaguchi, H., Ohga, S., Manabe, A., Harigae, H., Kunishima, S., Ishii, E., Kobayashi, M., Koike, K., Watanabe, K., Ito, E., Takata, M., Yabe, M., Ogawa, S., Miyano, S., Kojima, S.: Clinical utility of next-generation sequencing for inherited bone marrow failure syndromes. Genet Med, 19: 796-802 (2017).
    16. Nguyen, T. B., Sakata-Yanagimoto, M., Asabe, Y., Matsubara, D., Kano, J., Yoshida K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Izutsu, K., Nakamura, N., Takeuchi, K., Miyoshi, H., Ohshima, K., Minowa, T., Ogawa, S., Noguchi, M., Chiba, S.: Identification of cell-type-specific mutations in nodal T-cell lymphomas. Blood Cancer J, 7: e516 (2017).
    17. Nishizawa, S., Sakata-Yanagimoto, M., Hattori, K., Muto, H., Nguyen, T., Izutsu, K., Yoshida K., Ogawa, S., Nakamura, N., Chiba, S.: BCL6 locus is hypermethylated in angioimmunoblastic T-cell lymphoma. Int J Hematol, 105: 465-469 (2017).
    18. Seki, M., Kimura, S., Isobe, T., Yoshida K., Ueno, H., Nakajima-Takagi, Y., Wang, C., Lin, L., Kon, A., Suzuki, H., Shiozawa, Y., Kataoka, K., Fujii, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Shimamura, T., Masuda, K., Kawamoto, H., Ohki, K., Kato, M., Arakawa, Y., Koh, K., Hanada, R., Moritake, H., Akiyama, M., Kobayashi, R., Deguchi, T., Hashii, Y., Imamura, T., Sato, A., Kiyokawa, N., Oka, A., Hayashi, Y., Takagi, M., Manabe, A., Ohara, A., Horibe, K., Sanada, M., Iwama, A., Mano, H., Miyano, S., Ogawa, S., Takita, J.: Recurrent SPI1 (PU.1) fusions in high-risk pediatric T cell acute lymphoblastic leukemia. Nat Genet, 49: 1274-1281 (2017).
    19. Sekinaka, Y., Mitsuiki, N., Imai, K., Yabe, M., Yabe, H., Mitsui-Sekinaka, K., Honma, K., Takagi, M., Arai, A., Yoshida K., Okuno, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Muramatsu, H., Kojima, S., Hira, A., Takata, M., Ohara, O., Ogawa, S., Morio, T., Nonoyama, S.: Common Variable Immunodeficiency Caused by FANC Mutations. J Clin Immunol, 37: 434-444 (2017).
    20. Shiozawa, Y., Malcovati, L., Galli, A., Pellagatti, A., Karimi, M., Sato-Otsubo, A., Sato, Y., Suzuki, H., Yoshizato, T., Yoshida K., Shiraishi, Y., Chiba, K., Makishima, H., Boultwood, J., Hellstrom-Lindberg, E., Miyano, S., Cazzola, M., Ogawa, S.: Gene expression and risk of leukemic transformation in myelodysplasia. Blood, 130: 2642-2653 (2017).
    21. Takagi, M., Ogata, S., Ueno, H., Yoshida K., Yeh, T., Hoshino, A., Piao, J., Yamashita, M., Nanya, M., Okano, T., Kajiwara, M., Kanegane, H., Muramatsu, H., Okuno, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Bando, Y., Kato, M., Hayashi, Y., Miyano, S., Imai, K., Ogawa, S., Kojima, S., Morio, T.: Haploinsufficiency of TNFAIP3 (A20) by germline mutation is involved in autoimmune lymphoproliferative syndrome. J Allergy Clin Immunol, 139: 1914-1922 (2017).
    22. Takagi, M., Yoshida, M., Nemoto, Y., Tamaichi, H., Tsuchida, R., Seki, M., Uryu, K., Nishii, R., Miyamoto, S., Saito, M., Hanada, R., Kaneko, H., Miyano, S., Kataoka, K., Yoshida K., Ohira, M., Hayashi, Y., Nakagawara, A., Ogawa, S., Mizutani, S., Takita, J.: Loss of DNA Damage Response in Neuroblastoma and Utility of a PARP Inhibitor. J Natl Cancer Inst, 109:  (2017).
    23. Togasaki, E., Takeda, J., Yoshida K., Shiozawa, Y., Takeuchi, M., Oshima, M., Saraya, A., Iwama, A., Yokote, K., Sakaida, E., Hirase, C., Takeshita, A., Imai, K., Okumura, H., Morishita, Y., Usui, N., Takahashi, N., Fujisawa, S., Shiraishi, Y., Chiba, K., Tanaka, H., Kiyoi, H., Ohnishi, K., Ohtake, S., Asou, N., Kobayashi, Y., Miyazaki, Y., Miyano, S., Ogawa, S., Matsumura, I., Nakaseko, C., Naoe, T.: Frequent somatic mutations in epigenetic regulators in newly diagnosed chronic myeloid leukemia. Blood Cancer J, 7: e559 (2017).
    24. Uryu, K., Nishimura, R., Kataoka, K., Sato, Y., Nakazawa, A., Suzuki, H., Yoshida K., Seki, M., Hiwatari, M., Isobe, T., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Koh, K., Hanada, R., Oka, A., Hayashi, Y., Ohira, M., Kamijo, T., Nagase, H., Takimoto, T., Tajiri, T., Nakagawara, A., Ogawa, S., Takita, J.: Identification of the genetic and clinical characteristics of neuroblastomas using genome-wide analysis. Oncotarget, 8: 107513-107529 (2017).
    25. Yamato, G., Shiba, N., Yoshida K., Shiraishi, Y., Hara, Y., Ohki, K., Okubo, J., Okuno, H., Chiba, K., Tanaka, H., Kinoshita, A., Moritake, H., Kiyokawa, N., Tomizawa, D., Park, M. J., Sotomatsu, M., Taga, T., Adachi, S., Tawa, A., Horibe, K., Arakawa, H., Miyano, S., Ogawa, S., Hayashi, Y.: ASXL2 mutations are frequently found in pediatric AML patients with t(8;21)/ RUNX1-RUNX1T1 and associated with a better prognosis. Genes Chromosomes Cancer, 56: 382-393 (2017).
    26. Yoshida, M., Hamanoue, S., Seki, M., Tanaka, M., Yoshida K., Goto, H., Ogawa, S., Takita, J., Tanaka, Y.: Metachronous anaplastic sarcoma of the kidney and thyroid follicular carcinoma as manifestations of DICER1 abnormalities. Hum Pathol, 61: 205-209 (2017).
    27. Yoshizato, T., Nannya, Y., Atsuta, Y., Shiozawa, Y., Iijima-Yamashita, Y., Yoshida K., Shiraishi, Y., Suzuki, H., Nagata, Y., Sato, Y., Kakiuchi, N., Matsuo, K., Onizuka, M., Kataoka, K., Chiba, K., Tanaka, H., Ueno, H., Nakagawa, M. M., Przychodzen, B., Haferlach, C., Kern, W., Aoki, K., Itonaga, H., Kanda, Y., Sekeres, M. A., Maciejewski, J. P., Haferlach, T., Miyazaki, Y., Horibe, K., Sanada, M., Miyano, S., Makishima, H., Ogawa, S.: Genetic abnormalities in myelodysplasia and secondary acute myeloid leukemia: impact on outcome of stem cell transplantation. Blood, 129: 2347-2358 (2017).

2016年

    1. Arashiki, N., Takakuwa, Y., Mohandas, N., Hale, J., Yoshida K., Ogura, H., Utsugisawa, T., Ohga, S., Miyano, S., Ogawa, S., Kojima, S., Kanno, H.: ATP11C is a major flippase in human erythrocytes and its defect causes congenital hemolytic anemia. Haematologica, 101: 559-565 (2016).
    2. Ikeda, F., Toki, T., Kanezaki, R., Terui, K., Yoshida K., Kanno, H., Ohga, S., Ohara, A., Kojima, S., Ogawa, S., Ito, E.: ALDH2 polymorphism in patients with Diamond-Blackfan anemia in Japan. Int J Hematol, 103: 112-114 (2016).
    3. Imashuku, S., Muramatsu, H., Sugihara, T., Okuno, Y., Wang, X., Yoshida K., Kato, A., Kato, K., Tatsumi, Y., Hattori, A., Kita, S., Oe, K., Sueyoshi, A., Usui, T., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Ogawa, S., Kojima, S., Kanno, H.: PIEZO1 gene mutation in a Japanese family with hereditary high phosphatidylcholine hemolytic anemia and hemochromatosis-induced diabetes mellitus. Int J Hematol, 104: 125-129 (2016).
    4. Kataoka, K., Shiraishi, Y., Takeda, Y., Sakata, S., Matsumoto, M., Nagano, S., Maeda, T., Nagata, Y., Kitanaka, A., Mizuno, S., Tanaka, H., Chiba, K., Ito, S., Watatani, Y., Kakiuchi, N., Suzuki, H., Yoshizato, T., Yoshida K., Sanada, M., Itonaga, H., Imaizumi, Y., Totoki, Y., Munakata, W., Nakamura, H., Hama, N., Shide, K., Kubuki, Y., Hidaka, T., Kameda, T., Masuda, K., Minato, N., Kashiwase, K., Izutsu, K., Takaori-Kondo, A., Miyazaki, Y., Takahashi, S., Shibata, T., Kawamoto, H., Akatsuka, Y., Shimoda, K., Takeuchi, K., Seya, T., Miyano, S., Ogawa, S.: Aberrant PD-L1 expression through 3'-UTR disruption in multiple cancers. Nature, 534: 402-406 (2016).
    5. Kato, M., Seki, M., Yoshida K., Sato, Y., Oyama, R., Arakawa, Y., Kishimoto, H., Taki, T., Akiyama, M., Shiraishi, Y., Chiba, K., Tanaka, H., Mitsuiki, N., Kajiwara, M., Mizutani, S., Sanada, M., Miyano, S., Ogawa, S., Koh, K., Takita, J.: Genomic analysis of clonal origin of Langerhans cell histiocytosis following acute lymphoblastic leukaemia. Br J Haematol, 175: 169-172 (2016).
    6. Ki Kim, S., Ueda, Y., Hatano, E., Kakiuchi, N., Takeda, H., Goto, T., Shimizu, T., Yoshida K., Ikura, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Uemoto, S., Chiba, T., Ogawa, S., Marusawa, H.: TERT promoter mutations and chromosome 8p loss are characteristic of nonalcoholic fatty liver disease-related hepatocellular carcinoma. Int J Cancer, 139: 2512-2518 (2016).
    7. Kim, T., Yoshida K., Kim, Y. K., Tyndel, M. S., Park, H. J., Choi, S. H., Ahn, J. S., Jung, S. H., Yang, D. H., Lee, J. J., Kim, H. J., Kong, G., Ogawa, S., Zhang, Z., Kim, H. J., Kim, D. D.: Clonal dynamics in a single AML case tracked for 9 years reveals the complexity of leukemia progression. Leukemia, 30: 295-302 (2016).
    8. Kitamura, K., Okuno, Y., Yoshida K., Sanada, M., Shiraishi, Y., Muramatsu, H., Kobayashi, R., Furukawa, K., Miyano, S., Kojima, S., Ogawa, S., Kunishima, S.: Functional characterization of a novel GFI1B mutation causing congenital macrothrombocytopenia. J Thromb Haemost, 14: 1462-1469 (2016).
    9. Madan, V., Shyamsunder, P., Han, L., Mayakonda, A., Nagata, Y., Sundaresan, J., Kanojia, D., Yoshida K., Ganesan, S., Hattori, N., Fulton, N., Tan, K. T., Alpermann, T., Kuo, M. C., Rostami, S., Matthews, J., Sanada, M., Liu, L. Z., Shiraishi, Y., Miyano, S., Chendamarai, E., Hou, H. A., Malnassy, G., Ma, T., Garg, M., Ding, L. W., Sun, Q. Y., Chien, W., Ikezoe, T., Lill, M., Biondi, A., Larson, R. A., Powell, B. L., Lubbert, M., Chng, W. J., Tien, H. F., Heuser, M., Ganser, A., Koren-Michowitz, M., Kornblau, S. M., Kantarjian, H. M., Nowak, D., Hofmann, W. K., Yang, H., Stock, W., Ghavamzadeh, A., Alimoghaddam, K., Haferlach, T., Ogawa, S., Shih, L. Y., Mathews, V., Koeffler, H. P.: Comprehensive mutational analysis of primary and relapse acute promyelocytic leukemia. Leukemia, 30: 2430 (2016).
    10. Mansouri, L., Noerenberg, D., Young, E., Mylonas, E., Abdulla, M., Frick, M., Asmar, F., Ljungstrom, V., Schneider, M., Yoshida K., Skaftason, A., Pandzic, T., Gonzalez, B., Tasidou, A., Waldhueter, N., Rivas-Delgado, A., Angelopoulou, M., Ziepert, M., Arends, C. M., Couronne, L., Lenze, D., Baldus, C. D., Bastard, C., Okosun, J., Fitzgibbon, J., Dorken, B., Drexler, H. G., Roos-Weil, D., Schmitt, C. A., Munch-Petersen, H. D., Zenz, T., Hansmann, M. L., Strefford, J. C., Enblad, G., Bernard, O. A., Ralfkiaer, E., Erlanson, M., Korkolopoulou, P., Hultdin, M., Papadaki, T., Gronbaek, K., Lopez-Guillermo, A., Ogawa, S., Kuppers, R., Stamatopoulos, K., Stavroyianni, N., Kanellis, G., Rosenwald, A., Campo, E., Amini, R. M., Ott, G., Vassilakopoulos, T. P., Hummel, M., Rosenquist, R., Damm, F.: Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma. Blood, 128: 2666-2670 (2016).
    11. Merlevede, J., Droin, N., Qin, T., Meldi, K., Yoshida K., Morabito, M., Chautard, E., Auboeuf, D., Fenaux, P., Braun, T., Itzykson, R., de Botton, S., Quesnel, B., Commes, T., Jourdan, E., Vainchenker, W., Bernard, O., Pata-Merci, N., Solier, S., Gayevskiy, V., Dinger, M. E., Cowley, M. J., Selimoglu-Buet, D., Meyer, V., Artiguenave, F., Deleuze, J. F., Preudhomme, C., Stratton, M. R., Alexandrov, L. B., Padron, E., Ogawa, S., Koscielny, S., Figueroa, M., Solary, E.: Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents. Nat Commun, 7: 10767 (2016).
    12. Mitani, K., Nagata, Y., Sasaki, K., Yoshida K., Chiba, K., Tanaka, H., Shiraishi, Y., Miyano, S., Makishima, H., Nakamura, Y., Nakamura, Y., Ichikawa, M., Ogawa, S.: Somatic mosaicism in chronic myeloid leukemia in remission. Blood, 128: 2863-2866 (2016).
    13. Mori, T., Nagata, Y., Makishima, H., Sanada, M., Shiozawa, Y., Kon, A., Yoshizato, T., Sato-Otsubo, A., Kataoka, K., Shiraishi, Y., Chiba, K., Tanaka, H., Ishiyama, K., Miyawaki, S., Mori, H., Nakamaki, T., Kihara, R., Kiyoi, H., Koeffler, H. P., Shih, L. Y., Miyano, S., Naoe, T., Haferlach, C., Kern, W., Haferlach, T., Ogawa, S., Yoshida K.: Somatic PHF6 mutations in 1760 cases with various myeloid neoplasms. Leukemia, 30: 2270-2273 (2016).
    14. Nagata, Y., Kontani, K., Enami, T., Kataoka, K., Ishii, R., Totoki, Y., Kataoka, T. R., Hirata, M., Aoki, K., Nakano, K., Kitanaka, A., Sakata-Yanagimoto, M., Egami, S., Shiraishi, Y., Chiba, K., Tanaka, H., Shiozawa, Y., Yoshizato, T., Suzuki, H., Kon, A., Yoshida K., Sato, Y., Sato-Otsubo, A., Sanada, M., Munakata, W., Nakamura, H., Hama, N., Miyano, S., Nureki, O., Shibata, T., Haga, H., Shimoda, K., Katada, T., Chiba, S., Watanabe, T., Ogawa, S.: Variegated RHOA mutations in adult T-cell leukemia/lymphoma. Blood, 127: 596-604 (2016).
    15. Niemoller, C., Renz, N., Bleul, S., Blagitko-Dorfs, N., Greil, C., Yoshida K., Pfeifer, D., Follo, M., Duyster, J., Claus, R., Ogawa, S., Lubbert, M., Becker, H.: Single cell genotyping of exome sequencing-identified mutations to characterize the clonal composition and evolution of inv(16) AML in a CBL mutated clonal hematopoiesis. Leuk Res, 47: 41-46 (2016).
    16. Sakurai, M., Kasahara, H., Yoshida K., Yoshimi, A., Kunimoto, H., Watanabe, N., Shiraishi, Y., Chiba, K., Tanaka, H., Harada, Y., Harada, H., Kawakita, T., Kurokawa, M., Miyano, S., Takahashi, S., Ogawa, S., Okamoto, S., Nakajima, H.: Genetic basis of myeloid transformation in familial platelet disorder/acute myeloid leukemia patients with haploinsufficient RUNX1 allele. Blood Cancer J, 6: e392 (2016).
    17. Shiba, N., Yoshida K., Shiraishi, Y., Okuno, Y., Yamato, G., Hara, Y., Nagata, Y., Chiba, K., Tanaka, H., Terui, K., Kato, M., Park, M. J., Ohki, K., Shimada, A., Takita, J., Tomizawa, D., Kudo, K., Arakawa, H., Adachi, S., Taga, T., Tawa, A., Ito, E., Horibe, K., Sanada, M., Miyano, S., Ogawa, S., Hayashi, Y.: Whole-exome sequencing reveals the spectrum of gene mutations and the clonal evolution patterns in paediatric acute myeloid leukaemia. Br J Haematol, 175: 476-489 (2016).
    18. Tsujita, Y., Mitsui-Sekinaka, K., Imai, K., Yeh, T. W., Mitsuiki, N., Asano, T., Ohnishi, H., Kato, Z., Sekinaka, Y., Zaha, K., Kato, T., Okano, T., Takashima, T., Kobayashi, K., Kimura, M., Kunitsu, T., Maruo, Y., Kanegane, H., Takagi, M., Yoshida K., Okuno, Y., Muramatsu, H., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Kojima, S., Ogawa, S., Ohara, O., Okada, S., Kobayashi, M., Morio, T., Nonoyama, S.: Phosphatase and tensin homolog (PTEN) mutation can cause activated phosphatidylinositol 3-kinase delta syndrome-like immunodeficiency. J Allergy Clin Immunol, 138: 1672-1680 e1610 (2016).
    19. Uchi, R., Takahashi, Y., Niida, A., Shimamura, T., Hirata, H., Sugimachi, K., Sawada, G., Iwaya, T., Kurashige, J., Shinden, Y., Iguchi, T., Eguchi, H., Chiba, K., Shiraishi, Y., Nagae, G., Yoshida K., Nagata, Y., Haeno, H., Yamamoto, H., Ishii, H., Doki, Y., Iinuma, H., Sasaki, S., Nagayama, S., Yamada, K., Yachida, S., Kato, M., Shibata, T., Oki, E., Saeki, H., Shirabe, K., Oda, Y., Maehara, Y., Komune, S., Mori, M., Suzuki, Y., Yamamoto, K., Aburatani, H., Ogawa, S., Miyano, S., Mimori, K.: Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution. PLoS Genet, 12: e1005778 (2016).
    20. Volkert, S., Haferlach, T., Holzwarth, J., Zenger, M., Kern, W., Staller, M., Nagata, Y., Yoshida K., Ogawa, S., Schnittger, S., Haferlach, C.: Array CGH identifies copy number changes in 11% of 520 MDS patients with normal karyotype and uncovers prognostically relevant deletions. Leukemia, 30: 257-260 (2016).
    21. Yabe, M., Yabe, H., Morimoto, T., Fukumura, A., Ohtsubo, K., Koike, T., Yoshida K., Ogawa, S., Ito, E., Okuno, Y., Muramatsu, H., Kojima, S., Matsuo, K., Hira, A., Takata, M.: The phenotype and clinical course of Japanese Fanconi Anaemia infants is influenced by patient, but not maternal ALDH2 genotype. Br J Haematol, 175: 457-461 (2016).

2015年

    1. Ahn, J. S., Kim, H. J., Kim, Y. K., Jung, S. H., Yang, D. H., Lee, J. J., Lee, I. K., Kim, N. Y., Minden, M. D., Jung, C. W., Jang, J. H., Kim, H. J., Moon, J. H., Sohn, S. K., Won, J. H., Kim, S. H., Kim, N., Yoshida K., Ogawa, S., Kim, D. D.: Adverse prognostic effect of homozygous TET2 mutation on the relapse risk of acute myeloid leukemia in patients of normal karyotype. Haematologica, 100: e351-353 (2015).
    2. Chiba, K., Shiraishi, Y., Nagata, Y., Yoshida K., Imoto, S., Ogawa, S., Miyano, S.: Genomon ITDetector: a tool for somatic internal tandem duplication detection from cancer genome sequencing data. Bioinformatics, 31: 116-118 (2015).
    3. Garg, M., Nagata, Y., Kanojia, D., Mayakonda, A., Yoshida K., Haridas Keloth, S., Zang, Z. J., Okuno, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Ding, L. W., Alpermann, T., Sun, Q. Y., Lin, D. C., Chien, W., Madan, V., Liu, L. Z., Tan, K. T., Sampath, A., Venkatesan, S., Inokuchi, K., Wakita, S., Yamaguchi, H., Chng, W. J., Kham, S. K., Yeoh, A. E., Sanada, M., Schiller, J., Kreuzer, K. A., Kornblau, S. M., Kantarjian, H. M., Haferlach, T., Lill, M., Kuo, M. C., Shih, L. Y., Blau, I. W., Blau, O., Yang, H., Ogawa, S., Koeffler, H. P.: Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse. Blood, 126: 2491-2501 (2015).
    4. Hira, A., Yoshida K., Sato, K., Okuno, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Shimamoto, A., Tahara, H., Ito, E., Kojima, S., Kurumizaka, H., Ogawa, S., Takata, M., Yabe, H., Yabe, M.: Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia. Am J Hum Genet, 96: 1001-1007 (2015).
    5. Hoshino, A., Nomura, K., Hamashima, T., Isobe, T., Seki, M., Hiwatari, M., Yoshida K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Ogawa, S., Takita, J., Kanegane, H.: Aggressive transformation of anaplastic large cell lymphoma with increased number of ALK-translocated chromosomes. Int J Hematol, 101: 198-202 (2015).
    6. Huang, D., Nagata, Y., Grossmann, V., Radivoyevitch, T., Okuno, Y., Nagae, G., Hosono, N., Schnittger, S., Sanada, M., Przychodzen, B., Kon, A., Polprasert, C., Shen, W., Clemente, M. J., Phillips, J. G., Alpermann, T., Yoshida K., Nadarajah, N., Sekeres, M. A., Oakley, K., Nguyen, N., Shiraishi, Y., Shiozawa, Y., Chiba, K., Tanaka, H., Koeffler, H. P., Klein, H. U., Dugas, M., Aburatani, H., Miyano, S., Haferlach, C., Kern, W., Haferlach, T., Du, Y., Ogawa, S., Makishima, H.: BRCC3 mutations in myeloid neoplasms. Haematologica, 100: 1051-1057 (2015).
    7. Kanojia, D., Nagata, Y., Garg, M., Lee, D. H., Sato, A., Yoshida K., Sato, Y., Sanada, M., Mayakonda, A., Bartenhagen, C., Klein, H. U., Doan, N. B., Said, J. W., Mohith, S., Gunasekar, S., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Myklebost, O., Yang, H., Dugas, M., Meza-Zepeda, L. A., Silberman, A. W., Forscher, C., Tyner, J. W., Ogawa, S., Koeffler, H. P.: Genomic landscape of liposarcoma. Oncotarget, 6: 42429-42444 (2015).
    8. Kataoka, K., Nagata, Y., Kitanaka, A., Shiraishi, Y., Shimamura, T., Yasunaga, J., Totoki, Y., Chiba, K., Sato-Otsubo, A., Nagae, G., Ishii, R., Muto, S., Kotani, S., Watatani, Y., Takeda, J., Sanada, M., Tanaka, H., Suzuki, H., Sato, Y., Shiozawa, Y., Yoshizato, T., Yoshida K., Makishima, H., Iwanaga, M., Ma, G., Nosaka, K., Hishizawa, M., Itonaga, H., Imaizumi, Y., Munakata, W., Ogasawara, H., Sato, T., Sasai, K., Muramoto, K., Penova, M., Kawaguchi, T., Nakamura, H., Hama, N., Shide, K., Kubuki, Y., Hidaka, T., Kameda, T., Nakamaki, T., Ishiyama, K., Miyawaki, S., Yoon, S. S., Tobinai, K., Miyazaki, Y., Takaori-Kondo, A., Matsuda, F., Takeuchi, K., Nureki, O., Aburatani, H., Watanabe, T., Shibata, T., Matsuoka, M., Miyano, S., Shimoda, K., Ogawa, S.: Integrated molecular analysis of adult T cell leukemia/lymphoma. Nat Genet, 47: 1304-1315 (2015).
    9. Kawashima-Goto, S., Imamura, T., Seki, M., Kato, M., Yoshida K., Sugimoto, A., Kaneda, D., Fujiki, A., Miyachi, M., Nakatani, T., Osone, S., Ishida, H., Taki, T., Takita, J., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Ogawa, S., Hosoi, H.: Identification of a homozygous JAK3 V674A mutation caused by acquired uniparental disomy in a relapsed early T-cell precursor ALL patient. Int J Hematol, 101: 411-416 (2015).
    10. Kurtovic-Kozaric, A., Przychodzen, B., Singh, J., Konarska, M. M., Clemente, M. J., Otrock, Z. K., Nakashima, M., Hsi, E. D., Yoshida K., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Ogawa, S., Boultwood, J., Makishima, H., Maciejewski, J. P., Padgett, R. A.: PRPF8 defects cause missplicing in myeloid malignancies. Leukemia, 29: 126-136 (2015).
    11. Okuno, Y., Hoshino, A., Muramatsu, H., Kawashima, N., Wang, X., Yoshida K., Wada, T., Gunji, M., Toma, T., Kato, T., Shiraishi, Y., Iwata, A., Hori, T., Kitoh, T., Chiba, K., Tanaka, H., Sanada, M., Takahashi, Y., Nonoyama, S., Ito, M., Miyano, S., Ogawa, S., Kojima, S., Kanegane, H.: Late-Onset Combined Immunodeficiency with a Novel IL2RG Mutation and Probable Revertant Somatic Mosaicism. J Clin Immunol, 35: 610-614 (2015).
    12. Ono, R., Hasegawa, D., Hirabayashi, S., Kamiya, T., Yoshida K., Yonekawa, S., Ogawa, C., Hosoya, R., Toki, T., Terui, K., Ito, E., Manabe, A.: Acute megakaryoblastic leukemia with acquired trisomy 21 and GATA1 mutations in phenotypically normal children. Eur J Pediatr, 174: 525-531 (2015).
    13. Polprasert, C., Schulze, I., Sekeres, M. A., Makishima, H., Przychodzen, B., Hosono, N., Singh, J., Padgett, R. A., Gu, X., Phillips, J. G., Clemente, M., Parker, Y., Lindner, D., Dienes, B., Jankowsky, E., Saunthararajah, Y., Du, Y., Oakley, K., Nguyen, N., Mukherjee, S., Pabst, C., Godley, L. A., Churpek, J. E., Pollyea, D. A., Krug, U., Berdel, W. E., Klein, H. U., Dugas, M., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Yoshida K., Ogawa, S., Muller-Tidow, C., Maciejewski, J. P.: Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms. Cancer Cell, 27: 658-670 (2015).
    14. Sakaguchi, H., Muramatsu, H., Okuno, Y., Makishima, H., Xu, Y., Furukawa-Hibi, Y., Wang, X., Narita, A., Yoshida K., Shiraishi, Y., Doisaki, S., Yoshida, N., Hama, A., Takahashi, Y., Yamada, K., Miyano, S., Ogawa, S., Maciejewski, J. P., Kojima, S.: Aberrant DNA Methylation Is Associated with a Poor Outcome in Juvenile Myelomonocytic Leukemia. PLoS One, 10: e0145394 (2015).
    15. Seki, M., Nishimura, R., Yoshida K., Shimamura, T., Shiraishi, Y., Sato, Y., Kato, M., Chiba, K., Tanaka, H., Hoshino, N., Nagae, G., Shiozawa, Y., Okuno, Y., Hosoi, H., Tanaka, Y., Okita, H., Miyachi, M., Souzaki, R., Taguchi, T., Koh, K., Hanada, R., Kato, K., Nomura, Y., Akiyama, M., Oka, A., Igarashi, T., Miyano, S., Aburatani, H., Hayashi, Y., Ogawa, S., Takita, J.: Integrated genetic and epigenetic analysis defines novel molecular subgroups in rhabdomyosarcoma. Nat Commun, 6: 7557 (2015).
    16. Shiota, M., Yang, X., Kubokawa, M., Morishima, T., Tanaka, K., Mikami, M., Yoshida K., Kikuchi, M., Izawa, K., Nishikomori, R., Okuno, Y., Wang, X., Sakaguchi, H., Muramatsu, H., Kojima, S., Miyano, S., Ogawa, S., Takagi, M., Hata, D., Kanegane, H.: Somatic mosaicism for a NRAS mutation associates with disparate clinical features in RAS-associated leukoproliferative disease: a report of two cases. J Clin Immunol, 35: 454-458 (2015).
    17. Suzuki, H., Aoki, K., Chiba, K., Sato, Y., Shiozawa, Y., Shiraishi, Y., Shimamura, T., Niida, A., Motomura, K., Ohka, F., Yamamoto, T., Tanahashi, K., Ranjit, M., Wakabayashi, T., Yoshizato, T., Kataoka, K., Yoshida K., Nagata, Y., Sato-Otsubo, A., Tanaka, H., Sanada, M., Kondo, Y., Nakamura, H., Mizoguchi, M., Abe, T., Muragaki, Y., Watanabe, R., Ito, I., Miyano, S., Natsume, A., Ogawa, S.: Mutational landscape and clonal architecture in grade II and III gliomas. Nat Genet, 47: 458-468 (2015).
    18. Wang, R., Yoshida K., Toki, T., Sawada, T., Uechi, T., Okuno, Y., Sato-Otsubo, A., Kudo, K., Kamimaki, I., Kanezaki, R., Shiraishi, Y., Chiba, K., Tanaka, H., Terui, K., Sato, T., Iribe, Y., Ohga, S., Kuramitsu, M., Hamaguchi, I., Ohara, A., Hara, J., Goi, K., Matsubara, K., Koike, K., Ishiguro, A., Okamoto, Y., Watanabe, K., Kanno, H., Kojima, S., Miyano, S., Kenmochi, N., Ogawa, S., Ito, E.: Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia. Br J Haematol, 168: 854-864 (2015).
    19. Wang, X., Muramatsu, H., Okuno, Y., Sakaguchi, H., Yoshida K., Kawashima, N., Xu, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Saito, S., Nakazawa, Y., Masunari, T., Hirose, T., Elmahdi, S., Narita, A., Doisaki, S., Ismael, O., Makishima, H., Hama, A., Miyano, S., Takahashi, Y., Ogawa, S., Kojima, S.: GATA2 and secondary mutations in familial myelodysplastic syndromes and pediatric myeloid malignancies. Haematologica, 100: e398-401 (2015).
    20. Yamaguchi, H., Sakaguchi, H., Yoshida K., Yabe, M., Yabe, H., Okuno, Y., Muramatsu, H., Takahashi, Y., Yui, S., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Inokuchi, K., Ito, E., Ogawa, S., Kojima, S.: Clinical and genetic features of dyskeratosis congenita, cryptic dyskeratosis congenita, and Hoyeraal-Hreidarsson syndrome in Japan. Int J Hematol, 102: 544-552 (2015).
    21. Yang, X., Hoshino, A., Taga, T., Kunitsu, T., Ikeda, Y., Yasumi, T., Yoshida K., Wada, T., Miyake, K., Kubota, T., Okuno, Y., Muramatsu, H., Adachi, Y., Miyano, S., Ogawa, S., Kojima, S., Kanegane, H.: A female patient with incomplete hemophagocytic lymphohistiocytosis caused by a heterozygous XIAP mutation associated with non-random X-chromosome inactivation skewed towards the wild-type XIAP allele. J Clin Immunol, 35: 244-248 (2015).
    22. Yoshizato, T., Dumitriu, B., Hosokawa, K., Makishima, H., Yoshida K., Townsley, D., Sato-Otsubo, A., Sato, Y., Liu, D., Suzuki, H., Wu, C. O., Shiraishi, Y., Clemente, M. J., Kataoka, K., Shiozawa, Y., Okuno, Y., Chiba, K., Tanaka, H., Nagata, Y., Katagiri, T., Kon, A., Sanada, M., Scheinberg, P., Miyano, S., Maciejewski, J. P., Nakao, S., Young, N. S., Ogawa, S.: Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia. N Engl J Med, 373: 35-47 (2015).

2014年

    1. Becker, H., Yoshida K., Blagitko-Dorfs, N., Claus, R., Pantic, M., Abdelkarim, M., Niemoller, C., Greil, C., Hackanson, B., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Dohner, K., Schnittger, S., Henneke, P., Niemeyer, C. M., Flotho, C., Pfeifer, D., Ogawa, S., Lubbert, M.: Tracing the development of acute myeloid leukemia in CBL syndrome. Blood, 123: 1883-1886 (2014).
    2. Damm, F., Mylonas, E., Cosson, A., Yoshida K., Della Valle, V., Mouly, E., Diop, M., Scourzic, L., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Kikushige, Y., Davi, F., Lambert, J., Gautheret, D., Merle-Beral, H., Sutton, L., Dessen, P., Solary, E., Akashi, K., Vainchenker, W., Mercher, T., Droin, N., Ogawa, S., Nguyen-Khac, F., Bernard, O. A.: Acquired initiating mutations in early hematopoietic cells of CLL patients. Cancer Discov, 4: 1088-1101 (2014).
    3. Haferlach, T., Nagata, Y., Grossmann, V., Okuno, Y., Bacher, U., Nagae, G., Schnittger, S., Sanada, M., Kon, A., Alpermann, T., Yoshida K., Roller, A., Nadarajah, N., Shiraishi, Y., Shiozawa, Y., Chiba, K., Tanaka, H., Koeffler, H. P., Klein, H. U., Dugas, M., Aburatani, H., Kohlmann, A., Miyano, S., Haferlach, C., Kern, W., Ogawa, S.: Landscape of genetic lesions in 944 patients with myelodysplastic syndromes. Leukemia, 28: 241-247 (2014).
    4. Hasegawa, S., Imai, K., Yoshida K., Okuno, Y., Muramatsu, H., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Kojima, S., Ogawa, S., Morio, T., Mizutani, S., Takagi, M.: Whole-exome sequence analysis of ataxia telangiectasia-like phenotype. J Neurol Sci, 340: 86-90 (2014).
    5. Hosono, N., Makishima, H., Jerez, A., Yoshida K., Przychodzen, B., McMahon, S., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Sanada, M., Gomez-Segui, I., Verma, A. K., McDevitt, M. A., Sekeres, M. A., Ogawa, S., Maciejewski, J. P.: Recurrent genetic defects on chromosome 7q in myeloid neoplasms. Leukemia, 28: 1348-1351 (2014).
    6. Matsunawa, M., Yamamoto, R., Sanada, M., Sato-Otsubo, A., Shiozawa, Y., Yoshida K., Otsu, M., Shiraishi, Y., Miyano, S., Isono, K., Koseki, H., Nakauchi, H., Ogawa, S.: Haploinsufficiency of Sf3b1 leads to compromised stem cell function but not to myelodysplasia. Leukemia, 28: 1844-1850 (2014).
    7. Muto, H., Sakata-Yanagimoto, M., Nagae, G., Shiozawa, Y., Miyake, Y., Yoshida K., Enami, T., Kamada, Y., Kato, T., Uchida, K., Nanmoku, T., Obara, N., Suzukawa, K., Sanada, M., Nakamura, N., Aburatani, H., Ogawa, S., Chiba, S.: Reduced TET2 function leads to T-cell lymphoma with follicular helper T-cell-like features in mice. Blood Cancer J, 4: e264 (2014).
    8. Nakamoto-Matsubara, R., Sakata-Yanagimoto, M., Enami, T., Yoshida K., Yanagimoto, S., Shiozawa, Y., Nanmoku, T., Satomi, K., Muto, H., Obara, N., Kato, T., Kurita, N., Yokoyama, Y., Izutsu, K., Ota, Y., Sanada, M., Shimizu, S., Komeno, T., Sato, Y., Ito, T., Kitabayashi, I., Takeuchi, K., Nakamura, N., Ogawa, S., Chiba, S.: Detection of the G17V RHOA mutation in angioimmunoblastic T-cell lymphoma and related lymphomas using quantitative allele-specific PCR. PLoS One, 9: e109714 (2014).
    9. Sakata-Yanagimoto, M., Enami, T., Yoshida K., Shiraishi, Y., Ishii, R., Miyake, Y., Muto, H., Tsuyama, N., Sato-Otsubo, A., Okuno, Y., Sakata, S., Kamada, Y., Nakamoto-Matsubara, R., Tran, N. B., Izutsu, K., Sato, Y., Ohta, Y., Furuta, J., Shimizu, S., Komeno, T., Sato, Y., Ito, T., Noguchi, M., Noguchi, E., Sanada, M., Chiba, K., Tanaka, H., Suzukawa, K., Nanmoku, T., Hasegawa, Y., Nureki, O., Miyano, S., Nakamura, N., Takeuchi, K., Ogawa, S., Chiba, S.: Somatic RHOA mutation in angioimmunoblastic T cell lymphoma. Nat Genet, 46: 171-175 (2014).
    10. Sato, Y., Maekawa, S., Ishii, R., Sanada, M., Morikawa, T., Shiraishi, Y., Yoshida K., Nagata, Y., Sato-Otsubo, A., Yoshizato, T., Suzuki, H., Shiozawa, Y., Kataoka, K., Kon, A., Aoki, K., Chiba, K., Tanaka, H., Kume, H., Miyano, S., Fukayama, M., Nureki, O., Homma, Y., Ogawa, S.: Recurrent somatic mutations underlie corticotropin-independent Cushing's syndrome. Science, 344: 917-920 (2014).
    11. Seki, M., Yoshida K., Shiraishi, Y., Shimamura, T., Sato, Y., Nishimura, R., Okuno, Y., Chiba, K., Tanaka, H., Kato, K., Kato, M., Hanada, R., Nomura, Y., Park, M. J., Ishida, T., Oka, A., Igarashi, T., Miyano, S., Hayashi, Y., Ogawa, S., Takita, J.: Biallelic DICER1 mutations in sporadic pleuropulmonary blastoma. Cancer Res, 74: 2742-2749 (2014).
    12. Shen, W., Clemente, M. J., Hosono, N., Yoshida K., Przychodzen, B., Yoshizato, T., Shiraishi, Y., Miyano, S., Ogawa, S., Maciejewski, J. P., Makishima, H.: Deep sequencing reveals stepwise mutation acquisition in paroxysmal nocturnal hemoglobinuria. J Clin Invest, 124: 4529-4538 (2014).
    13. Yoshida K., Ogawa, S.: Splicing factor mutations and cancer. Wiley Interdiscip Rev RNA, 5: 445-459 (2014).

2013年

    1. Damm, F., Chesnais, V., Nagata, Y., Yoshida K., Scourzic, L., Okuno, Y., Itzykson, R., Sanada, M., Shiraishi, Y., Gelsi-Boyer, V., Renneville, A., Miyano, S., Mori, H., Shih, L. Y., Park, S., Dreyfus, F., Guerci-Bresler, A., Solary, E., Rose, C., Cheze, S., Prebet, T., Vey, N., Legentil, M., Duffourd, Y., de Botton, S., Preudhomme, C., Birnbaum, D., Bernard, O. A., Ogawa, S., Fontenay, M., Kosmider, O.: BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders. Blood, 122: 3169-3177 (2013).
    2. Gomez-Segui, I., Makishima, H., Jerez, A., Yoshida K., Przychodzen, B., Miyano, S., Shiraishi, Y., Husseinzadeh, H. D., Guinta, K., Clemente, M., Hosono, N., McDevitt, M. A., Moliterno, A. R., Sekeres, M. A., Ogawa, S., Maciejewski, J. P.: Novel recurrent mutations in the RAS-like GTP-binding gene RIT1 in myeloid malignancies. Leukemia, 27: 1943-1946 (2013).
    3. Hira, A., Yabe, H., Yoshida K., Okuno, Y., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Nakamura, J., Kojima, S., Ogawa, S., Matsuo, K., Takata, M., Yabe, M.: Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients. Blood, 122: 3206-3209 (2013).
    4. Kitamura, K., Yoshida K., Shiraishi, Y., Chiba, K., Tanaka, H., Furukawa, K., Miyano, S., Ogawa, S., Kunishima, S.: Normal neutrophil myosin IIA localization in an immunofluorescence analysis can rule out MYH9 disorders. J Thromb Haemost, 11: 2071-2073 (2013).
    5. Kon, A., Shih, L. Y., Minamino, M., Sanada, M., Shiraishi, Y., Nagata, Y., Yoshida K., Okuno, Y., Bando, M., Nakato, R., Ishikawa, S., Sato-Otsubo, A., Nagae, G., Nishimoto, A., Haferlach, C., Nowak, D., Sato, Y., Alpermann, T., Nagasaki, M., Shimamura, T., Tanaka, H., Chiba, K., Yamamoto, R., Yamaguchi, T., Otsu, M., Obara, N., Sakata-Yanagimoto, M., Nakamaki, T., Ishiyama, K., Nolte, F., Hofmann, W. K., Miyawaki, S., Chiba, S., Mori, H., Nakauchi, H., Koeffler, H. P., Aburatani, H., Haferlach, T., Shirahige, K., Miyano, S., Ogawa, S.: Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms. Nat Genet, 45: 1232-1237 (2013).
    6. Kunishima, S., Okuno, Y., Yoshida K., Shiraishi, Y., Sanada, M., Muramatsu, H., Chiba, K., Tanaka, H., Miyazaki, K., Sakai, M., Ohtake, M., Kobayashi, R., Iguchi, A., Niimi, G., Otsu, M., Takahashi, Y., Miyano, S., Saito, H., Kojima, S., Ogawa, S.: ACTN1 mutations cause congenital macrothrombocytopenia. Am J Hum Genet, 92: 431-438 (2013).
    7. Makishima, H., Yoshida K., Nguyen, N., Przychodzen, B., Sanada, M., Okuno, Y., Ng, K. P., Gudmundsson, K. O., Vishwakarma, B. A., Jerez, A., Gomez-Segui, I., Takahashi, M., Shiraishi, Y., Nagata, Y., Guinta, K., Mori, H., Sekeres, M. A., Chiba, K., Tanaka, H., Muramatsu, H., Sakaguchi, H., Paquette, R. L., McDevitt, M. A., Kojima, S., Saunthararajah, Y., Miyano, S., Shih, L. Y., Du, Y., Ogawa, S., Maciejewski, J. P.: Somatic SETBP1 mutations in myeloid malignancies. Nat Genet, 45: 942-946 (2013).
    8. Ohba, R., Furuyama, K., Yoshida K., Fujiwara, T., Fukuhara, N., Onishi, Y., Manabe, A., Ito, E., Ozawa, K., Kojima, S., Ogawa, S., Harigae, H.: Clinical and genetic characteristics of congenital sideroblastic anemia: comparison with myelodysplastic syndrome with ring sideroblast (MDS-RS). Ann Hematol, 92: 1-9 (2013).
    9. Saida, S., Watanabe, K., Sato-Otsubo, A., Terui, K., Yoshida K., Okuno, Y., Toki, T., Wang, R., Shiraishi, Y., Miyano, S., Kato, I., Morishima, T., Fujino, H., Umeda, K., Hiramatsu, H., Adachi, S., Ito, E., Ogawa, S., Ito, M., Nakahata, T., Heike, T.: Clonal selection in xenografted TAM recapitulates the evolutionary process of myeloid leukemia in Down syndrome. Blood, 121: 4377-4387 (2013).
    10. Sakaguchi, H., Okuno, Y., Muramatsu, H., Yoshida K., Shiraishi, Y., Takahashi, M., Kon, A., Sanada, M., Chiba, K., Tanaka, H., Makishima, H., Wang, X., Xu, Y., Doisaki, S., Hama, A., Nakanishi, K., Takahashi, Y., Yoshida, N., Maciejewski, J. P., Miyano, S., Ogawa, S., Kojima, S.: Exome sequencing identifies secondary mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia. Nat Genet, 45: 937-941 (2013).
    11. Sato, Y., Yoshizato, T., Shiraishi, Y., Maekawa, S., Okuno, Y., Kamura, T., Shimamura, T., Sato-Otsubo, A., Nagae, G., Suzuki, H., Nagata, Y., Yoshida K., Kon, A., Suzuki, Y., Chiba, K., Tanaka, H., Niida, A., Fujimoto, A., Tsunoda, T., Morikawa, T., Maeda, D., Kume, H., Sugano, S., Fukayama, M., Aburatani, H., Sanada, M., Miyano, S., Homma, Y., Ogawa, S.: Integrated molecular analysis of clear-cell renal cell carcinoma. Nat Genet, 45: 860-867 (2013).
    12. Shiraishi, Y., Sato, Y., Chiba, K., Okuno, Y., Nagata, Y., Yoshida K., Shiba, N., Hayashi, Y., Kume, H., Homma, Y., Sanada, M., Ogawa, S., Miyano, S.: An empirical Bayesian framework for somatic mutation detection from cancer genome sequencing data. Nucleic Acids Res, 41: e89 (2013).
    13. Yoshida K., Sanada, M., Ogawa, S.: Deep sequencing in cancer research. Jpn J Clin Oncol, 43: 110-115 (2013).
    14. Yoshida K., Toki, T., Okuno, Y., Kanezaki, R., Shiraishi, Y., Sato-Otsubo, A., Sanada, M., Park, M. J., Terui, K., Suzuki, H., Kon, A., Nagata, Y., Sato, Y., Wang, R., Shiba, N., Chiba, K., Tanaka, H., Hama, A., Muramatsu, H., Hasegawa, D., Nakamura, K., Kanegane, H., Tsukamoto, K., Adachi, S., Kawakami, K., Kato, K., Nishimura, R., Izraeli, S., Hayashi, Y., Miyano, S., Kojima, S., Ito, E., Ogawa, S.: The landscape of somatic mutations in Down syndrome-related myeloid disorders. Nat Genet, 45: 1293-1299 (2013).

2012年

    1. Meggendorfer, M., Roller, A., Haferlach, T., Eder, C., Dicker, F., Grossmann, V., Kohlmann, A., Alpermann, T., Yoshida K., Ogawa, S., Koeffler, H. P., Kern, W., Haferlach, C., Schnittger, S.: SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML). Blood, 120: 3080-3088 (2012).
    2. Takita, J., Yoshida K., Sanada, M., Nishimura, R., Okubo, J., Motomura, A., Hiwatari, M., Oki, K., Igarashi, T., Hayashi, Y., Ogawa, S.: Novel splicing-factor mutations in juvenile myelomonocytic leukemia. Leukemia, 26: 1879-1881 (2012).

2011年

    1. Yoshida K., Sanada, M., Kato, M., Kawahata, R., Matsubara, A., Takita, J., Shih, L. Y., Mori, H., Koeffler, H. P., Ogawa, S.: A nonsense mutation of IDH1 in myelodysplastic syndromes and related disorders. Leukemia, 25: 184-186 (2011).
    2. Yoshida K., Sanada, M., Shiraishi, Y., Nowak, D., Nagata, Y., Yamamoto, R., Sato, Y., Sato-Otsubo, A., Kon, A., Nagasaki, M., Chalkidis, G., Suzuki, Y., Shiosaka, M., Kawahata, R., Yamaguchi, T., Otsu, M., Obara, N., Sakata-Yanagimoto, M., Ishiyama, K., Mori, H., Nolte, F., Hofmann, W. K., Miyawaki, S., Sugano, S., Haferlach, C., Koeffler, H. P., Shih, L. Y., Haferlach, T., Chiba, S., Nakauchi, H., Miyano, S., Ogawa, S.: Frequent pathway mutations of splicing machinery in myelodysplasia. Nature, 478: 64-69 (2011).

2010年

    1. Yoshida K., Hasegawa, D., Takusagawa, A., Kato, I., Ogawa, C., Echizen, N., Ohkoshi, K., Yamaguchi, T., Hosoya, R., Manabe, A.: Bullous exudative retinal detachment due to infiltration of leukemic cells in a child with acute lymphoblastic leukemia. Int J Hematol, 92: 535-537 (2010).

2009年

    1. Watanabe, S., Miyake, K., Ogawa, C., Matsumoto, H., Yoshida K., Hirabayashi, S., Hasegawa, D., Inoue, T., Kizu, J., Machida, R., Ohara, A., Hosoya, R., Manabe, A.: The ex vivo production of ammonia predicts L-asparaginase biological activity in children with acute lymphoblastic leukemia. Int J Hematol, 90: 347-352 (2009).
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