1. Akimi Yonezawa, Kana Shimomura, Koji Okamoto and Haruna Takeda*
   Inhibition of BRD4 attenuated IFNg-induced apoptosis in colorectal cancer organoids. BMC Cancer (2025). *Corresponding author
2. Naoko Iida, Yukari Muranaka, Jun Won Park, Shigeki Sekine, Neal G. Copeland, Nancy A. Jenkins, Yuichi Shiraishi, Masanobu Oshima and Haruna Takeda*. Cancer Gene Therapy (2024), *corresponding author
3. Kana Shimomura, Naoko Hattori, Naoko Iida, Yukari Muranaka, Kotomi Sato, Yuichi Shiraishi, Yasuhito Arai, Natsuko Hama, Tatsuhiro Shibata, Daichi Narushima, Mamoru Kato, Hiroyuki Takamaru, Koji Okamoto, Haruna Takeda*. Sleeping Beauty transposon mutagenesis identified genes and pathways involved in inflammation-associated colon tumor development. Nature Communications 14(1) 2023, *corresponding author
   DOI: https://doi.org/10.1038/s41467-023-42228-z（外部サイトにリンクします）
4. Kazuhiro Nishiyama, Hitomi Nishinakamura, Hideyuki Takeshima, Liu Yuyu, Chihiro Takeuchi, Naoko Hattori, Haruna Takeda, Satoshi Yamashita, Mika Wakabayashi, Kotomi Sato, Kazutaka Obama, Toshikazu Ushijima. Mouse methylation profiles for leukocyte cell types, and estimation of leukocyte fractions in inflamed gastrointestinal DNA samples. PLOS ONE 18(10) e0290034-e0290034 2023
5. Yamamoto D, Oshima H, Wang D, Takeda H, Kita K, Lei X, Nakayama M, Murakami K, Ohama T, Takemura H, Toyota M, Suzuki H, Inaki N and Oshima M. Characterization of RNF43 frameshift mutations that drive Wnt ligand- and R-spondin-dependent colon cancer. J. Pathol. 257, 2022
6. Haruna Takeda*. A Platform for Validating Colorectal Cancer Driver Genes Using Mouse Organoids. Front. Genet. 12, 2021, *corresponding author
7. Takeda H*, Jenkins NA and Copeland NG. Identification of cancer driver genes using Sleeping Beauty transposon mutagenesis. Review, Cancer Science, 112(6):2089-2096, 2021 *corresponding author
8. Murakami K, Terakado Y, Saito K, Jomen Y, Takeda H, Oshima M et al. A genome-scale CRISPR screen reveals factors regulating Wnt-dependent renewal of mouse gastric epithelial cells. PNAS, 118, 2021.
9. Takeda H*, Kataoka S, Nakayama M, Ali MAE, Oshima H, Yamamoto D et al. CRISPR-Cas9-mediated gene knockout in intestinal tumor organoids provides functional validation for colorectal cancer driver genes. PNAS, 116: 15635-15644, 2019. *corresponding author

2017年以前