コンテンツにジャンプ
logo_hojin_J_2c.png

トップページ > 研究 > 研究支援センター(CRAS) > 生物統計部 > 2025年 実績

2025年 実績

  1. Takahashi S, Taki T, Nakamura N, Ura A, Kubota S, Miyoshi T, Tane K, Matsumura Y, Samejima J, Aokage K, Wakabayashi M, Sasahara Y, Nagamine M, Kojima M, Sakashita S, Sakamoto N, Hayashi T, Takamochi K, Suzuki K, Tsuboi M, Ishii G. Translational Analysis of NSD3 Gene Amplification in Lung Squamous Cell Carcinoma: Clinical and Prognostic Insights From Histopathologic Analysis of Patient Samples. Journal of thoracic oncology. 2026;21(1):135-149. [Pubmed]
  2. Maruki Y, Yatabe Y, Mizoguchi C, de Almeida KY, Sookprasert A, Akewanlop C, Chen MH, Sirachainan E, Tu DV, Malik RA, Charoentum C, Hoo HFS, Yusak S, Liu TH, Ramachandran R, Sunpaweravong P, Voon PJ, Bakar NA, Mizusawa J, Okuma HS, Nakamura K, Morizane C, Okusaka T. FGFR2 Fusions or Rearrangements in Young Intrahepatic and Perihilar Cholangiocarcinoma Patients: Key Genetic Insights From a Pan-Asian Study. Hepatology research. 2026;56(1):78-88. [Pubmed]
  3. Terada N, Nihei K, Aizawa R, Narita S, Kojima T, Shiota M, Akamatsu S, Kimura T, Inoue T, Sugimoto M, Sekino Y, Sasaki K, Shibata T, Fukuda H, Nishiyama H, Kitamura H, Mizowaki T. Protocol summary of a randomized controlled phase III trial for confirming the superiority of local radiotherapy for prostate cancer patients with high-volume metastasis sensitive to hormonal therapy: the JCOG2011 (HimeRT study). Japanese journal of clinical oncology. 2026;56(1):104-109. [Pubmed]
  4. Matsuda S, Tsushima T, Kawakubo H, Hironaka S, Tsubosa Y, Sakanaka K, Oguma J, Kadowaki S, Tsunoda S, Hara H, Koyanagi K, Yamaguchi T, Harada K, Takahashi M, Minashi K, Baba E, Sasaki K, Machida R, Takeuchi H. Safety and efficacy of conversion therapy for metastatic esophageal cancer: exploratory analysis of JCOG1314. Esophagus. 2026;23(1):111-119. [Pubmed]
  5. Hanaoka M, Kataoka K, Mizusawa J, Ouchi A, Shimada Y, Inomata M, Hamaguchi T, Takii Y, Takayama Y, Ito M, Fujita S, Suwa Y, Ikenaga M, Souda H, Tanaka C, Sano Y, Tsukamoto S, Takashima A, Kinugasa Y, Kanemitsu Y. Risk of peritoneal recurrence following laparoscopic versus open surgery for stage II/III colorectal cancer: An integrated analysis of three Phase III randomized controlled trials (JCOG2310AS2). European journal of surgical oncolog. 2026;52(1):110545. [Pubmed]
  6. Hayakawa M, Nakajima H, Harano K, Watanabe S, Tsuchimochi S, Uematsu M, Fukuda M, Funasaka C, Kondoh C, Matsubara N, Naito Y, Hosono A, Wakabayashi M, Takahashi K, Tanabe H, Mukohara T. Impact of platinum-free interval and bevacizumab on second-line chemotherapy following progression on first-line PARP inhibitor maintenance in advanced ovarian cancer: A retrospective cohort study. Gynecologic oncology. 2026;204:70-78. [Pubmed]
  7. Matsumoto T, Tanegashima T, Takeuchi A, Sasaki K, Ogawa G, Kojima T, Kawahara T, Matsui Y, Nishiyama N, Nishiyama H, Kitamura H, Eto M. A randomized controlled phase III trial on continued or paused PD-1 pathway blockade for patients with advanced renal cell carcinoma (JCOG1905, STOP study): a study protocol. Japanese journal of clinical oncology. 2026;56(3):352-357. [Pubmed]
  8. Tsuchida S, Taki T, Nomura K, Suzuki K, Hashimoto H, Kubota S, Miyoshi T, Tane K, Matsumura Y, Samejima J, Aokage K, Wakabayashi M, Sasahara Y, Nagamine M, Sakashita S, Sakamoto N, Suzuki K, Tsuboi M, Ishii G. Extranodal extension in lung adenocarcinoma: pathological insights and its implication as a histological marker of clinical aggressiveness. British journal of cancer. 2026;134(4):567-576. [Pubmed]
  9. Sano Y, Miyazaki K, Yamaguchi M, Taguchi S, Machida R, Kawabata K, Fukuda H, Shimada K, Nagai H, Munakata W, Maruyama D. Protocol digest of a randomized phase III study of pola-R-CHP/high-dose methotrexate/IT vs. pola-R-CHP/IT for newly diagnosed diffuse large B-cell lymphoma with high risk of central nervous system relapse: JCOG2201 (PREMIER). Japanese journal of clinical oncology. 2026;56(3):358-363. [Pubmed]
  10. Fujimoto A, Munakata W, Ogawa G, Machida R, Suzuki T, Shimada K, Kobayashi T, Ohmachi K, Kinoshita T, Ando K, Maruyama D, Nagai H. Impact of Achieving Progression-Free Survival 24 on Subsequent Overall Survival in Diffuse Large B-Cell Lymphoma Patients. Cancer science. 2026;117(3):769-776. [Pubmed]
  11. Kitaguchi D, Fuse N, Wakabayashi M, Kosugi N, Ishikawa Y, Hayashi K, Hasegawa H, Takeshita N, Ito M. Exploring the Impact of an Artificial Intelligence-Based Intraoperative Image Navigation System in Laparoscopic Surgery on Clinical Outcomes: A Protocol for a Multicenter Randomized Controlled Trial. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes. 2026;67(1):38-45. [Pubmed]
  12. Mitsui T, Takizawa K, Kadota T, Ogawa G, Ono H, Hasuike N, Ishihara R, Yoshio T, Oyama T, Kikuchi D, Inokuchi Y, Toya Y, Hikichi T, Kanzaki H, Hatta W, Yoshikawa T, Abe S, Terashima M, Yano T. Factors associated with technical difficulty in endoscopic submucosal dissection for undifferentiated early gastric cancer: post hoc analysis of JCOG1009月10日10. Surgical endoscopy. 2026;40(3):2568-2577. [Pubmed]
  13. Kita R, Kato K, Machida R, Ito Y, Daiko H, Kawakubo H, Sasaki K, Fukuda H, Kimura Y, Akiyoshi K, Koyanagi K, Hara H, Minashi K, Amagai K, Abe T, Matsuda S, Tsushima T, Takeuchi H. Optimal Timing of Surgery Following Neoadjuvant Therapy for Surgical and Oncological Outcomes in Advanced Esophageal Squamous Cell Carcinoma: An Exploratory Analysis of JCOG1109. Annals of surgical oncology. 2026;33(6):5327-5338. [Pubmed]
  14. Kanemitsu Y, Shimizu Y, Mizusawa J, Inaba Y, Tsukamoto S, Takashima A, Ohue M, Komori K, Shiomi A, Shiozawa M, Suwa Y, Suto T, Kinugasa Y, Takii Y, Bando H, Kobatake T, Inomata M, Shimada Y, Katayama H, Fukuda H. Randomized Phase II/III Trial Comparing Hepatectomy, Followed by mFOLFOX6 With Hepatectomy Alone for Liver Metastasis From Colorectal Cancer: Long-Term Results of JCOG0603. Journal of clinical oncology. 2026;44:1395-1400. [Pubmed]
  15. Kitamura H, Tsukamoto T, Kakehi Y, Mizusawa J, Shibata T, Sasaki K, Tanikawa T, Hashine K, Fujimoto K, Masumori N, Kobayashi T, Habuchi T, Kimura T, Sugimoto M, Takahashi A, Adachi H, Matsui Y, Hatakeyama S, Ito A, Eto M, Nishiyama H. Active Surveillance Versus Intravesical Bacillus Calmette-Guérin for High-grade T1 Bladder Cancer with Negative Second Transurethral Resection: The Randomized Noninferiority Phase 3 JCOG1019 Trial. European urology. 2026;89:437-445. [Pubmed]
  16. Shigematsu H, Fujisawa T, Hara F, Iwata H, Ishiba T, Ozaki Y, Sakai T, Sagara Y, Shimomura A, Sudo K, Terata K, Naito Y, Nozawa K, Sasaki K, Mitome N, Sadachi R, Shibata T, Shien T. Clinical complete response and predictive factors in HER2-positive early breast cancer treated with neoadjuvant chemotherapy aimed at omission of surgery: an exploratory analysis of the JCOG1806 trial. International journal of clinical oncology. 2026;31:528-536. [Pubmed]
  17. Yanagimoto H, Nakachi K, Ikeda M, Konishi M, Ogawa G, Sano Y, Nomura T, Yanagibashi H, Shibuya K, Shirakawa H, Takahashi A, Sakamoto Y, Makino I, Hatano E, Gotohda N, Kamei K, Kobayashi S, Imaoka H, Ozaka M, Terashima T, Okusaka T, Furuse J, Ueno M. Original Study: Risk Factors for Early Recurrence in Patients With Biliary Tract Cancers Who Underwent Curative Resection: An Exploratory Subgroup Analysis of JCOG1202. Journal of surgical oncology. 2026;133:326-337. [Pubmed]
  18. Kan M, Uchida S, Sudo T, Yokozuka K, Nakaya Y, Abe A, Kurosaki H, Ogane Y, Watabe K, Sakai M, Sekine Y, Ouchi M, Yokoyama M, Ohyama H, Kato J. Touch imprint cytology for rapid on-site evaluation in endoscopic ultrasound-guided tissue acquisition of pancreatic tumors: diagnostic performance and practical value-a single-center retrospective observational study from Japan. Clinical endoscopy. 2026. [Pubmed]
  19. Sasaki K, Ishiba T, Nishibuchi I, Hara F, Sekino Y, Machida R, Shibata T, Kawahara D, Sagara Y, Naito Y, Terata K, Ozaki Y, Shimomura A, Sakai T, Shigematsu H, Sudo K, Nozawa K, Yoshimura M, Shikama N, Mizowaki T, Shien T. A randomized controlled trial of metastasis-directed therapy for oligometastases in breast cancer: OLIGAMI trial (JCOG2110). Japanese journal of clinical oncology. 2026;56:659-665. [Pubmed]
  20. Shien T, Ishitobi M, Sasaki K, Tanaka K, Shimomura A, Tsukioki T, Sagara Y, Kimura Y, Terata K, Ishiba T, Yasojima H, Ono M, Goda K, Naito Y, Fujisawa T, Hara F, Ogawa G, Fukuda H, Iwata H. Efficacy and prognostic predictors of primary systemic therapy for de novo Stage IV breast cancer. Exploratory analysis of JCOG1017 PRIM-BC. Breast cancer (Tokyo, Japan). 2026;33:396-406. [Pubmed]
  21. Sato F, Uemura K, Mizusawa J, Matsuyama Y, Morikawa Y. Adaptive Seamless Phase II/III Randomization Test Considering Treatment Group Selection Based on Short-Term Binary Outcomes. Statistics in medicine. 2026;45:e70400. [Pubmed]
  22. Sano Y, Kajikawa R, Mizusawa J, Ioka T, Ozaka M, Nakamura S, Ito Y, Furuse J, Kobayashi S, Fukuda H, Okusaka T, Ikeda M, Miwa H, Sasahira N, Nagashima F, Ohkawa K, Yamazaki K, Kanai M, Yamashita T, Hara K, Takayama Y, Komatsu Y, Fujimori N, Hama N, Kamata K, Hisano T, Shimizu S, Tobimatsu K, Maeda S, Ueno M. Comparison of chemoradiotherapy and gemcitabine plus nab-paclitaxel for locally advanced pancreatic cancer: an integrated analysis of two randomized phase II trials (JCOG2408A). BMC cancer. 2026;26:363. [Pubmed]
  23. Kadota T, Kawachi H, Fujii S, Yoshio T, Abe S, Nagami Y, Mizuno KI, Kikuchi D, Yamamoto Y, Ishihara R, Oyama T, Nakanishi H, Katada C, Yamamoto Y, Satomi T, Hatta W, Kitagawa Y, Hirasawa K, Urabe Y, Nakamura J, Sugawara N, Tanaka T, Muto M, Tanaka M, Ikeno T, Wakabayashi M, Nakano K, Inaba A, Yano T. Long-term outcome after endoscopic resection for esophageal squamous cell carcinoma invading muscularis mucosa without lymphovascular invasion: a multicenter retrospective study. Gastrointestinal endoscopy. 2026. [Pubmed]
  24. Inoue M, Ogasawara S, Asahara K, Sato R, Watanabe S, Anzai H, Tsubura K, Watabe T, Fujiya M, Akatsuka T, Izai R, Katayama K, Sawada M, Tsuchiya T, Miwa C, Yoshino R, Yonemoto T, Fujimoto K, Unozawa H, Yumita S, Kanzaki H, Koroki K, Kobayashi K, Nakamura M, Kanogawa N, Nakamoto S, Yokoyama M, Kato J, Moriguchi M, Aramaki T, Morimoto N. Durable Disease Control With Atezolizumab Plus Bevacizumab but Limited Post-Progression Outcomes: A Multicenter Real-World Study in Advanced Hepatocellular Carcinoma. Cancer medicine. 2026;15:e71655. [Pubmed]
  25. Kinoshita T, Takayama S, Fujisawa T, Watanabe K, Yamamoto N, Shien T, Ito M, Takahashi M, Futamura M, Onishi T, Yoshida M, Takahashi M, Doihara H, Yorikane E, Ohata K, Machida R, Tsuda H. Radiofrequency Ablation for Early Stage Breast Cancer as a Potential Alternative to Partial Mastectomy: 5-Year Results from the Multiple-Center, Single-Arm, Phase 3 RAFAELO Study (NCCH1409). Annals of surgical oncology. 2026;33:4584-4594. [Pubmed]
  26. Itou C, Kimura S, Murakami S, Urikura A, Yokoyama M, Mochizuki S, Sone M. Transcatheter 4-Dimensional versus 3-Dimensional Computed Tomography Angiography to Guide Selective Arterial Embolization of Renal Cell Carcinoma: A Comparative Study. Journal of vascular and interventional radiology. 2026;37:108604. [Pubmed]
  27. Kubo E, Satomi E, Mukohara T, Fuse N, Wakabayashi M, Tsukada Y, Ishiki H, Takayama S, Kanemitsu Y, Kishita I, Kobayashi K, Kurihara C, Hirano N, Ikeno T, Miura T, Sato A. Randomized Controlled Trial to Relieve Pain of Chemotherapy-Induced Peripheral Neuropathy by Magnetic Field: SMILE Study. Cancers. 2026;18時58分1. [Pubmed]
  28. Kita R, Mitome N, Mizusawa J, Kawabata K, Sasaki K, Sano Y, Uozumi T, Katayama H, Fukuda H. Sustainable platform for cross-disease evaluation: Integrated JCOG trials database (JCOG2509A). European journal of surgical oncology. 2026;52:111495. [Pubmed]
  29. Okada M, Sato J, Funasaka C, Yamamoto N, Sasaki T, Yokoyama M, Hamada A, Doi T, Mano H. Study protocol for a phase I investigator-initiated clinical trial of E7820 in Japanese patients with unresectable solid tumours: CIRCUS trial (NCCH2303). Japanese journal of clinical oncology. 2026. [Pubmed]
  30. Kimura K, Kuwata T, Hiraoka Y, Matsukawa M, Tomozawa C, Aitani M, Komura Y, Miki I, Wakabayashi M, Furui Y, Kondo H, Saigoh K, Yamamoto Y, Akagi K, Narimatsu H, Yokono M, Amano S, Muto K, Nagami F, Kato K, Yamashita R, Imoto I, Kosugi S, Hirata M, Yoshino T, Nakamura Y. Psychological distress and cancer worry in unaffected relatives undergoing cascade testing with multigene panel testing. Journal of human genetics. 2026. [Pubmed]
  31. Oashi K, Ogata D, Yokoyama M, Sano Y, Fukuda H, Hiura A, Nakamura Y, Uehara J, Takahashi A, Namikawa K, Mori S, Nakano E, Maeda T, Miyagawa T, Yoshino K, Funakoshi T, Kiniwa Y, Nakagawa T, Shibayama Y, Uchi H, Maeda T, Muto I, Maruyama A, Takenouchi T, Hatta N, Yamazaki N. Efficacy and safety of pazopanib in patients with paclitaxel-pretreated primary cutaneous angiosarcoma in Japan: Results of the Japan Clinical Oncology Group single-arm confirmatory trial (JCOG1605). The British journal of dermatology. 2026. [Pubmed]
  32. Booka E, Kato K, Ito Y, Daiko H, Koyanagi K, Yamamoto M, Ogata T, Fukuda T, Fujita T, Abe T, Takahashi M, Watanabe M, Ichikawa H, Hihara J, Kanda M, Hamai Y, Tsushima T, Machida R, Sasaki K, Takeuchi H. Prognostic Impact of Postoperative Complications After Neoadjuvant Therapy Followed by Esophagectomy for Esophageal Cancer: An Exploratory Analysis of Phase III Trial JCOG1109. Annals of surgery. 2026. [Pubmed]
  33. Yamada T, Kurokawa Y, Mizusawa J, Inoue K, Hasegawa Y, Ehara K, Hiki N, Tsutsui S, Ito S, Fukuda H, Takiguchi S, Doki Y, Boku N, Yoshikawa T, Terashima M, Sano T, Sasako M. Risk Factors for Body Weight Loss After Gastrectomy for Gastric Cancer Analyzed From the JCOG1001 Phase III Trial. Annals of gastroenterological surgery. 2026;10時45分2-459. [Pubmed]
  34. Hirao M, Kurokawa Y, Kajikawa R, Mizusawa J, Kawabata K, Tokunaga M, Kuroda K, Sakuramoto S, Yasufuku I, Matsushita H, Takiguchi S, Doki Y, Yoshikawa T, Terashima M. Influence of Hospital and Surgeon Volumes on Clinical Outcomes After Standard Surgery for Advanced Gastric Cancer: Supplementary Analysis of the Multicenter Randomized Phase III Trial JCOG1001. Annals of gastroenterological surgery. 2026;10時44分3-451. [Pubmed]
  35. Hirotaki K, Makita K, Tomizawa K, Wakabayashi M, Hojo H, Nakamura M, Ito M. Dosimetric evaluation of biaxially rotational dynamic radiation therapy and swing-fixed non-coplanar volumetric modulated arc therapy with OXRAY in prostate cancer: a comparative study. Radiation oncology journal. 2026;44:8-15. [Pubmed]
  36. Watanuki R, Sakai H, Kimura Y, Yoshida A, Ozaki Y, Kataoka A, Uehiro N, Fushimi A, Kamio H, Ikeno T, Wakabayashi M, Iida M, Kawaguchi T, Tsurutani J, Takano T. Characteristics of a multigene assay (MammaPrint/Blueprint) to predict early recurrence of hormone receptor-positive, HER2-negative breast cancer: a case‒control study (WJOG16722B). Breast cancer (Tokyo, Japan). 2026;33:693-704. [Pubmed]
  37. Zhou Y, Nakamura M, Makita K, Hiroshima Y, Hirata H, Rachi T, Baba H, Wakabayashi M, Ikeda M, Gotohda N, Zenda S. Clinical Outcomes of Proton Beam Therapy for Hepatocellular Carcinoma Adjacent to the Gastrointestinal Tract. Anticancer research. 2026;46:2175-2185. [Pubmed]
  38. Kenmotsu H, Niho S, Tsuboi M, Wakabayashi M, Ishii G, Asahina H, Watanabe K, Kiyoshima M, Iwata T, Nakamura Y, Nakahara Y, Chen-Yoshikawa TF, Nishino K, Nishio W, Yokoyama T, Mitome N, Asamura H, Ohe Y, Watanabe SI. Five-year overall survival in JCOG1205月12日06: irinotecan or etoposide plus cisplatin for resected high-grade neuroendocrine carcinoma of the lung. Lung cancer (Amsterdam, Netherlands). 2026;216時10分9386. [Pubmed]
  39. 水澤 純基. 【がん臨床試験に携わる方が知るべき新常識】QOLデータ解析の新常識(estimandを中心に). Precision Medicine. 2026;pp 1148-1151. [link]
  40. Ozaki Y, Mitome N, Tokuda E, Sasada S, Shimomura A, Sasaki K, Kajikawa R, Funasaka C, Yoshida A, Takayama S, Ishiba T, Sakai T, Sagara Y, Shigematsu H, Sudo K, Terata K, Naito Y, Fujisawa T, Saji S, Iwata H, Hara F, Shien T. Randomized Phase III Trial for Evaluating the Efficacy of Adjuvant Abemaciclib in Patients With Locoregional Recurrence of Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer: JCOG2313, AURA Trial. JCO Oncology Advances. 2026;e2500219. [link]
  41. Matsuda S, Takeuchi H, Kato K, Machida R, Ito Y, Tsubosa Y, Daiko H, Koyanagi K, Ogata T, Fukuda T, Fujita T, Abe T, Bamba T, Watanabe M, Kawakubo H, Shibuya Y, Otsubo D, Kakisita T, Hashimoto T, Sasaki K, Kitagawa Y. Prognostic Impact of Thoracic Duct Resection in Patients Who Underwent Transthoracic Esophagectomy Following Neoadjuvant Therapy for Esophageal Squamous Cell Carcinoma: Exploratory Analysis of JCOG1109. Annals of surgical oncology. 2025;32:293-301. [Pubmed]
  42. Umemura S, Udagawa H, Ikeda T, Murakami H, Daga H, Toyozawa R, Kozuki T, Sakakibara-Konishi J, Ohe Y, Morise M, Kato T, Shingyoji M, Hara S, Furuya N, Teranishi S, Takata S, Miyamoto S, Nakachi I, Wakabayashi M, Nomura S, Sato A, Ishii G, Tsuchihara K, Sugiyama E, Kirita K, Sakai T, Shibata Y, Izumi H, Nosaki K, Zenke Y, Matsumoto S, Yoh K, Niho S, Goto K. Clinical Significance of a Prospective Large Genomic Screening for SCLC: The Genetic Classification and a Biomarker-Driven Phase 2 Trial of Gedatolisib. Journal of thoracic oncology. 2025;20時17分7-193. [Pubmed]
  43. Watanabe T, Murano T, Ikematsu H, Shinmura K, Wakabayashi M, Minakata N, Maasa S, Mitsui T, Yamashita H, Inaba A, Sunakawa H, Nakajo K, Kadota T, Yano T. Impact of advanced endoscopy training on colonoscopy quality and efficiency. DEN open. 2025;5:e70027. [Pubmed]
  44. Kobayashi T, Ishizawa K, Machida R, Sadachi R, Sasaki K, Kim H, Kataoka K, Munakata W, Fukuhara N, Nagai H. Obinutuzumab maintenance versus observation for patients with newly diagnosed high tumor burden follicular lymphoma who achieved complete metabolic response after obinutuzumab plus bendamustine induction therapy: a multicenter, randomized, phase III study (JCOG2008, MAIN study). Japanese journal of clinical oncology. 2025;55:666-671. [Pubmed]
  45. Sasaki T, Kuno H, Nomura K, Muramatsu Y, Aokage K, Samejima J, Taki T, Goto E, Wakabayashi M, Furuya H, Taguchi H, Kobayashi T. CZT-based photon-counting-detector CT with deep-learning reconstruction: image quality and diagnostic confidence for lung tumor assessment. Japanese journal of radiology. 2025;43:1132-1144. [Pubmed]
  46. Bertsimas D, Koulouras A, Nagata H, Gao C, Mizusawa J, Kanemitsu Y, Margonis GA. The R.O.A.D. to clinical trial emulation. Research square. 2025;rs.3.rs-5576146. [Pubmed]
  47. Uematsu M, Nakajima H, Miyake H, Wakabayashi M, Funasaka C, Kondoh C, Harano K, Matsubara N, Hosono A, Naito Y, Sakamoto N, Kojima M, Onishi T, Ishii G, Mukohara T. Digitally quantified area of residual tumor after neoadjuvant chemotherapy in HER2-positive breast cancer. Breast cancer (Tokyo, Japan). 2025;32:716-727. [Pubmed]
  48. Watanuki R, Sakai H, Takehara Y, Yoshida A, Hayashi N, Ozaki Y, Kataoka A, Uehiro N, Kamio H, Onishi M, Fushimi A, Ikeno T, Wakabayashi M, Iida M, Kawaguchi T, Takano T. Risk factors for early recurrence in patients with hormone receptor-positive, HER2-negative breast cancer: a retrospective cohort study in Japan (WJOG15721B). Breast cancer (Tokyo, Japan). 2025;32:757-772. [Pubmed]
  49. Shiga K, Shibata T, Miyata T. Evaluation of drug lag and drug loss in Japan: participation in global phase III oncology trials. International journal of clinical oncology. 2025;30:1109-1117. [Pubmed]
  50. Bando H, Takeda Y, Misumi T, Nishikawa T, Wakabayashi M, Yamazaki K, Oki E, Douillard JY, Punt CJA, Koopman M, Van Cutsem E, Bokemeyer C, Venook AP, Lenz HJ, Maehara Y, Andre T, Shi Q, de Gramont A, Yoshino T. Associations between early tumor shrinkage/depth of response and survival from the ARCAD database. JNCI cancer spectrum. 2025;9:pkaf042. [Pubmed]
  51. Saito H, Jindai K, Shibata T, Sonoda M, Iiyama T. How to build a better clinical trial ecosystem for future infectious disease emergencies in Japan: Findings from a narrative review and stakeholder meetings. Global health & medicine. 2025;7:96-105. [Pubmed]
  52. Bamba T, Kato K, Daiko H, Ito Y, Kajiwara T, Fujita T, Miyata H, Machida R, Sasaki K, Takeuchi H, Kitagawa Y. Postoperative Recurrence Pattern of Clinical Stage I Esophageal Cancer After Esophagectomy with Two- or Three-Field Lymph Node Dissection: Supplementary Analysis from JCOG0502. Annals of surgical oncology. 2025;32:5928-5935. [Pubmed]
  53. Kadota T, Fujii R, Koyama S, Kotani D, Yoda Y, Fukutani M, Suzuki M, Wakabayashi M, Ikeno T, Sunakawa H, Nakamura Y, Kawazoe A, Irie T, Fuse N, Sato A, Yano T, Shitara K. A phase Ib study of photoimmunotherapy with ASP-1929 in combination with nivolumab for advanced gastric cancer (GE-PIT, EPOC1901). Gastric cancer. 2025;28:718-724. [Pubmed]
  54. Sekino Y, Moritani K, Mizusawa J, Shida D, Shunsuke T, Hamaguchi T, Takashima A, Shiomi A, Ito M, Takayama Y, Kinouchi M, Fujita S, Shiozawa M, Ueno H, Ikeda S, Takii Y, Sano Y, Kataoka T, Fukuda H, Kanemitsu Y. Protocol digest of a single-arm confirmatory trial for less intensive postoperative surveillance in low-risk colorectal cancer patients: JCOG1915 (less study). Japanese journal of clinical oncology. 2025;55:970-974. [Pubmed]
  55. Nomura S, Sekino Y, Shiraishi Y, Toi Y, Yoshida T, Tanaka K, Suzuki S, Azuma K, Hara S, Morita R, Niho S, Koda T, Toyozawa R, Yoh K, Kurata T, Fukuda H, Ohe Y, Okamoto I. A treatment-related death predictive score for treatment-naïve advanced non-small cell lung cancer. Lung cancer (Amsterdam, Netherlands). 2025;24時10分8584. [Pubmed]
  56. Mizutani T, Takei H, Kunitoh H, Wakabayashi M, Sekino Y, Tsuboi M, Ikeda N, Asamura H, Okada M, Takahama M, Ohde Y, Okami J, Shiono S, Aokage K, Watanabe SI. Longitudinal assessment of functional independence of older adults after lung cancer surgery: Final results of the JCOG1710A prospective cohort study. Journal of geriatric oncology. 2025;16時10分2268. [Pubmed]
  57. Yoshikawa S, Kikuchi K, Nozawa K, Nakai Y, Fukuda H, Shibata T, Machida R, Hamaguchi T, Takashima A, Takatsuka S, Nishina T, Kawazoe A, Tsushima T, Takahashi M, Hasegawa A, Masuishi T, Yamazaki N, Kiyohara Y. Facial Skin With Conspicuous Enlarged Pores Closely Related to Severity of Facial Acneiform Rash and Therapeutic Effects of EGFR Inhibitors in RAS Wild-Type Metastatic Colorectal Cancer: Ancillary Analysis of FAEISS Study (NCCH1512). The Journal of dermatology. 2025;52:1227-1231. [Pubmed]
  58. Horii S, Saito H, Shibata T, Sonoda M, Iiyama T, Jindai K. Principal investigators' experience of COVID-19 therapeutic clinical trials in Japan: a qualitative study. BMJ open. 2025;15:e097611. [Pubmed]
  59. Hirotaki K, Makita K, Nakamura M, Wakabayashi M, Kitou S, Ninomiya T, Ito M. Dosimetric Study of Biaxially Rotational Dynamic Radiation Therapy for Hippocampal-Sparing Whole Brain Irradiation. Cancers. 2025;17時19分49. [Pubmed]
  60. Mitome N, Hattori A, Suzuki K, Wakabayashi M, Sekino Y, Isaka T, Yotsukura M, Aokage K, Fukuda H, Watanabe SI. A multi-institutional randomized phase III trial of lobectomy versus segmentectomy for radiologically solid-predominant non-small cell lung cancer with a ground-glass opacity and tumor diameter > 2 cm and ≦ 3 cm: JCOG2217 (STRONG). Japanese journal of clinical oncology. 2025;55:1184-1188. [Pubmed]
  61. Tsubokawa N, Tsutani Y, Hishida T, Saji H, Wakabayashi M, Endo M, Mimae T, Miyoshi T, Isaka T, Isaka M, Hattori A, Yoshioka H, Nakajima R, Yotsukura M, Maniwa T, Sekino Y, Fukuda H, Nakagawa K, Aokage K, Watanabe SI, Okada M. Quality comparison of mediastinal lymph node dissection between video-assisted thoracic surgery and open thoracotomy: a supplementary analysis of the phase 3 Japan Clinical Oncology Group 1413 trial†. European journal of cardio-thoracic surgery. 2025;67:ezaf206. [Pubmed]
  62. Shien T, Hara F, Aogi K, Yanagida Y, Tsuneizumi M, Yamamoto N, Matsumoto H, Suto A, Watanabe K, Harao M, Kanbayashi C, Itoh M, Kadoya T, Anan K, Maeda S, Sasaki K, Ogawa G, Saji S, Fukuda H, Iwata H. Primary tumour resection plus systemic therapy versus systemic therapy alone in metastatic breast cancer (JCOG1017, PRIM-BC): a randomised clinical trial. British journal of cancer. 2025;133:625-632. [Pubmed]
  63. Zhao X, Takenaka S, Iuchi S, Kitaguchi D, Wakabayashi M, Sato K, Arakaki S, Sasaki K, Kosugi N, Takeshita N, Takeshita N, Sakamoto S, Ichikawa T, Ito M. Automatic recognition of surgical phase of robot-assisted radical prostatectomy based on artificial intelligence deep-learning model and its application in surgical skill evaluation: a joint study of 18 medical education centers. Surgical endoscopy. 2025;39:5623-5635. [Pubmed]
  64. Kiyota N, Mizusawa J, Zenda S, Yokota T, Fujimoto Y, Wasano K, Kodaira T. Caution Needed Before Adopting Reduced-Dose Elective Neck Irradiation in Head and Neck Cancer: A Response to UPGRADE-RT. Journal of clinical oncology. 2025;43:2952-2953. [Pubmed]
  65. Suzuki Y, Ikeda M, Mizusawa J, Sano Y, Morizane C, Okusaka T, Kobayashi S, Imaoka H, Terashima T, Okano N, Miwa H, Todaka A, Shimizu S, Mizuno N, Satoi S, Sano K, Tobimatsu K, Katanuma A, Ozaka M, Ueno M. Comparison of clinical features by primary site in patients with biliary tract cancer who received gemcitabine-based chemotherapy: an exploratory analysis of JCOG1113. International journal of clinical oncology. 2025;30:2053-2062. [Pubmed]
  66. Ohba A, Ozaka M, Mizusawa J, Okusaka T, Kobayashi S, Yamashita T, Ikeda M, Yasuda I, Sugimori K, Sasahira N, Ikezawa K, Miki I, Okano N, Mizuno N, Furukawa M, Shirakawa H, Sano Y, Katayama H, Furuse J, Ueno M. Modified Fluorouracil, Leucovorin, Irinotecan, and Oxaliplatin or S-1, Irinotecan, and Oxaliplatin Versus Nab-Paclitaxel + Gemcitabine in Metastatic or Recurrent Pancreatic Cancer (GENERATE, JCOG1611): A Randomized, Open-Label, Phase II/III Trial. Journal of clinical oncology. 2025;43:3345-3354. [Pubmed]
  67. Hirotaki K, Motegi K, Moriya S, Wakabayashi M, Sakae T, Ito M, Zenda S. Dosimetric and robustness evaluation of biaxially rotational dynamic radiation therapy with robust optimization. Journal of applied clinical medical physics. 2025;26:e70194. [Pubmed]
  68. Funasaka C, Naito Y, Kubota H, Ishiguro Y, Fuse N, Wakabayashi M, Sato A, Yuda J, Ishii G, Suzuki T, Takenouchi K, Nakatsura T, Morita K, Inada Y, Tanaka M, Nakazawa Y, Yagyu S, Doi T. Trial in progress: phase I study of non-viral gene-modified CAR-T cell therapy for malignant solid tumors expressing EPHB4 receptor (CARTiEr). Frontiers in oncology. 2025;15時16分33324. [Pubmed]
  69. Tateishi A, Horinouchi H, Kouno N, Takeda K, Takasawa K, Mizuno T, Okubo Y, Yoshida Y, Miyake M, Kusumoto M, Inaba K, Igaki H, Yatabe Y, Mukai M, Mihara N, Nishino J, Kuchiba A, Shibata T, Shiraishi K, Watanabe SI, Komatsu M, Kohno T, Ohe Y, Hamamoto R. Prediction recurrence in stage I epidermal growth factor receptor-mutated non-small cell lung cancer using multi-modal data. Lung cancer (Amsterdam, Netherlands). 2025;27時10分8727. [Pubmed]
  70. Hirotaki K, Makita K, Wakabayashi M, Hojo H, Kitou S, Tomizawa K, Ito M, Sakae T. Improvement in Coronary Dose Distribution Using Dynamic Swing Arc in Volumetric-modulated Arc Therapy During Esophageal Cancer Radiotherapy. In vivo (Athens, Greece). 2025;39:2824-2831. [Pubmed]
  71. Ohmachi K, Kinoshita T, Maruyama D, Machida R, Sano Y, Yamauchi N, Fukuhara N, Uchida T, Yamamoto K, Miyazaki K, Tsukamoto N, Iida S, Yoshida I, Imaizumi Y, Suzuki Y, Yoshida S, Masaki Y, Murayama T, Yakushijin Y, Suehiro Y, Nosaka K, Dobashi N, Kuroda J, Takamatsu Y, Munakata W, Ando K, Ishizawa K, Ogura M, Yoshino T, Hotta T, Tsukasaki K, Tobinai K, Nagai H. Final results of JCOG0601 randomized trial of R-CHOP versus CHOP combined with dose-dense rituximab for diffuse large B-cell lymphoma. Japanese journal of clinical oncology. 2025;55:1357-1364. [Pubmed]
  72. Sugata K, Aokage K, Taki T, Nomura K, Wakabayashi M, Miyoshi T, Tane K, Samejima J, Sasahara Y, Nagamine M, Kojima M, Sakashita S, Sakamoto N, Tsuboi M, Ishii G. Impact of tumor cell burden beyond the elastic layer on prognosis in T2aN0M0 non-small cell lung cancer with visceral pleural invasion. Lung cancer (Amsterdam, Netherlands). 2025;28時10分8759. [Pubmed]
  73. Sakamoto Y, Morizane C, Okusaka T, Mizusawa J, Hiraoka N, Shirota T, Ueno M, Kobayashi S, Ikeda M, Imaoka H, Ozaka M, Okano N, Yamaguchi H, Mizuno N, Nishina T, Katanuma A, Kojima Y, Gotoh K, Okamura K, Kawamoto Y, Sugimori K, Terashima T, Sugimoto R, Shirakawa H, Furuse J. Impact of ERCC1 on the outcomes of chemotherapy in advanced biliary tract cancer. Scientific reports. 2025;15時33分862. [Pubmed]
  74. Yamamoto K, Bando H, Misumi T, Nishikawa T, Wakabayashi M, Yamazaki K, Maehara Y, Oki E, Saltz LB, Douillard JY, Punt CJ, Koopman M, Van Cutsem E, Bokemeyer C, Venook AP, Heinemann V, Cremolini C, Randolph Hecht J, Schmoll HJ, Nakayama G, Lenz HJ, Andre T, Shi Q, de Gramont A, Shitara K, Yoshino T. Chronological survival improvement over time with oxaliplatin-based chemotherapy plus targeted agents in metastatic colorectal cancer: An ARCAD database study. European journal of cancer (Oxford, England : 1990). 2025;230:116034. [Pubmed]
  75. Masuishi T, Taniguchi H, Kotani D, Bando H, Komatsu Y, Shinozaki E, Sunakawa Y, Satoh T, Nishina T, Esaki T, Wakabayashi M, Nomura S, Takahashi K, Ono H, Hirano N, Fujishiro N, Fuse N, Sato A, Sakamoto Y, Kuramoto N, Miki I, Ichiki H, Nakamura Y, Sharma G, Skrzypczak S, Schultz E, Kingsford C, Ohtsu A, Yoshino T. A multicenter phase II study of eribulin for BRAF V600E mutant metastatic colorectal cancer: the BRAVERY study (EPOC1701). ESMO open. 2025;10時10分5839. [Pubmed]
  76. Takeuchi H, Machida R, Ando M, Tsubosa Y, Kikuchi H, Kawakubo H, Noma K, Ueno M, Tsushima T, Bamba T, Fujita T, Hamai Y, Kakishita T, Daiko H, Koyanagi K, Matsuda S, Kato K, Sasaki K, Kita R, Kitagawa Y. Thoracoscopic versus open oesophagectomy for patients with oesophageal cancer (JCOG1409 MONET): a multicentre, open-label, randomised, controlled, phase 3, non-inferiority trial. The lancet. Gastroenterology & hepatology. 2025;10時11分04-1116. [Pubmed]
  77. Kataoka J, Tsukada Y, Wakabayashi M, Kitaguchi D, Hasegawa H, Ikeda K, Nishizawa Y, Ito M. Identification of Risk Factors in Postoperative Urinary Dysfunction for Rectal Gastrointestinal Stromal Tumors. Annals of gastroenterological surgery. 2025;9時12分43-1252. [Pubmed]
  78. Watanabe SI, Wakabayashi M, Sekino Y, Nakagawa K. A Response to the Letter to the Editor: Disparities in Locoregional Relapse Across Tumor Sites After Segmentectomy. Journal of thoracic oncology. 2025;20:e118-e119. [Pubmed]
  79. Hirotaki K, Makita K, Wakabayashi M, Nakamura M, Tomizawa K, Kitou S, Ninomiya T, Ito M. Dosimetric comparison between biaxially rotational dynamic radiation therapy and volumetric modulated arc therapy for locally advanced non-small cell lung cancer. Journal of thoracic disease. 2025;17:7915-7923. [Pubmed]
  80. Amdal CD, Falk RS, Alanya A, Schlichting M, Roychoudhury S, Bhatnagar V, Wintner LM, Regnault A, Ingelgård A, Coens C, le Cessie S, Holzner B, Chang J, Taphoorn M, Cislo P, Giesinger JM, Cappelleri JC, Pawar V, Ten Seldam S, Papadopoulos EJ, Calvert MJ, Joseph KL, Bottomley A, Griebsch I, Arraras JI, Astrup GL, Basch E, Belančić A, Brundage M, Campbell A, Rerhou Rantell K, Cocks K, Cherny N, Eremenco S, Ferrer M, Fiero MH, Gerlinger C, Goetghebeur E, Grouven U, Lauer A, Aiyegbusi OL, Machingura A, Mizusawa J, Molenberghs G, Aa Petersen M, Reijneveld JC, Ringash J, Rumpold G, Rutherford C, Quinten C, Sail K, Sasseville M, Sauerbrei W, Schiel A, Smith AW, Snyder C, Velikova G, Wang XS, Bjordal K, Pe M. SISAQOL-IMI consensus-based guidelines to design, analyse, interpret, and present patient-reported outcomes in cancer clinical trials. The Lancet. Oncology. 2025;26:e683-e693. [Pubmed]
  81. Nakao T, Harano K, Wakabayashi M, Taki T, Watanabe R, Tanabe H, Mukohara T. Prognostic Value of Tertiary Lymphoid Structures in Epithelial Ovarian Carcinoma. Anticancer research. 2025;45:5543-5555. [Pubmed]
  82. Sakanaka K, Sasaki K, Tsushima T, Machida R, Hamai Y, Watanabe A, Kawabata K, Matsuda S, Kato K, Fukuda H, Takeuchi H. Study protocol of a randomized controlled phase II trial comparing nivolumab, ipilimumab plus radiotherapy versus nivolumab plus ipilimumab for advanced or recurrent esophageal cancer: Japan Clinical Oncology Group study JCOG2311 (ART NOUVEAU). BMC cancer. 2025;26:34. [Pubmed]
  83. Machida R, Sakamaki K, Ohigashi T, Sozu T. Dynamic Prediction of Analysis Timing in Clinical Trials Using Joint Models of Longitudinal and Time-to-Event Data. Statistics in medicine. 2025;44:e70312. [Pubmed]
  84. Hirano H, Hirata K, Honma Y, Morizane C, Machida N, Kato K, Okusaka T, Boku N, Sekine S, Hiraoka N, Mizusawa J, Sano Y, Shibuya Y, Takahashi M, Fujimori N, Nomura M, Doki Y, Ueno M, Yoshikawa T, Takeuchi H. Prognostic factors for overall survival in advanced digestive neuroendocrine carcinoma treated with first-line cisplatin-based chemotherapy: a post hoc analysis of JCOG1213. ESMO gastrointestinal oncology. 2025;8時10分0178. [Pubmed]
  85. 水澤 純基, 山本 精一郎. 論文図表を読む作法PREMIUM はじめて出会う実験&解析法も正しく解釈!生命科学・医学論文をスラスラ読むためのFigure事典. 実験医学. 2025.
  86. Hashimoto T, Hirano H, Takashima A, Sekine S, Kanato K, Mizusawa J, Fukuda H, Tsukamoto S, Kanemitsu Y. Circulating tumor DNA as a predictor of response and prognosis in rectal cancer treated with total neoadjuvant therapy (JCOG2010A1-ctTNT study). ESMO Gastrointestinal Oncology. 2025;100212. [link]
  87. Tsushima T, Hironaka S, Tsubosa Y, Machida R, Kato K, Kadowaki S, Nomura M, Hara H, Kitagawa Y, Koyanagi K, Kajiwara T, Takegawa N, Matsubara H, Iwatsuki M, Kimura Y, Sugimura K, Hasegawa H, Kojima T, Matsuda S, Sasaki K, Takeuchi H. First-Line Docetaxel Once Every 2 Week With Cisplatin Plus Fluorouracil for Metastatic Esophageal Cancer: A Multicenter, Randomized Controlled Phase III Study (JCOG1314, MIRACLE). JCO Oncology Advances. 2025;e2500064. [link]
ページの先頭へ