レジデント業績

2016年

1. Aramaki N, Ishii G, Yamada E, Morise M, Aokage K, Kojima M, Hishida T, Yoshida J, Ikeda N, Tsuboi M, Ochiai A. Drastic morphological and molecular differences between lymph node micrometastatic tumors and macrometastatic tumors of lung adenocarcinoma. J Cancer Res Clin Oncol, 142(1):37-46, 2016.1
2. Naito M, Tsuboi M. [Recent Status of Postoperative Adjuvant Chemotherapy after Completely Resected Lung Cancer]. Gan To Kagaku Ryoho, 43(2):165-9, 2016.2
3. Neri S, Hashimoto H, Kii H, Watanabe H, Masutomi K, Kuwata T, Date H, Tsuboi M, Goto K, Ochiai A, Ishii G. Cancer cell invasion driven by extracellular matrix remodeling is dependent on the properties of cancer-associated fibroblasts. J Cancer Res Clin Oncol, 142(2):437-46, 2016.2
4. Sekihara K, Hishida T, Ikemura S, Saruwatari K, Morise M, Kuwata T, Fujii S, Kojima M, Ochiai A, Funai K, Aokage K, Yoshida J, Tsuboi M, Ishii G. The association of intravascular stromal cells with prognosis in high-grade neuroendocrine carcinoma of the lung. J Cancer Res Clin Oncol, 142(5):905-12, 2016.5
5. Hata K, Yoshida J, Udagawa H, Hashimoto H, Fujii S, Hishida T, Kuwata T, Aokage K, Kojima M, Ochiai A, Suzuki K, Tsuboi M, Ishii G. The difference in Ezrin-pAkt signaling axis between lepidic and papillary predominant invasive adenocarcinomas of the lung. J Cancer Res Clin Oncol, 142(7):1421-1430. 2016.7
6. Suzuki S, Aokage K, Hishida T, Yoshida J, Kuwata T, Yamauchi C, Tsuboi M, Ishii G. Interstitial growth as an aggressive growth pattern in primary lung cancer. J Cancer Res Clin Oncol, 142(7):1591-8. 2016.7
7. Naito M, Aokage K, Saruwatari K, Hisakane K, Miyoshi T, Hishida T, Yoshida J, Masato S, Kojima M, Kuwata T, Fujii S, Ochiai A, Sato Y, Tsuboi M, Ishii G. Microenvironmental changes in the progression from adenocarcinoma in situ to minimally invasive adenocarcinoma and invasive lepidic predominant adenocarcinoma of the lung. Lung Cancer. 100:53-62, 2016.10
8. Shimada Y, Suzuki K, Okada M, Nakayama H, Ito H, Mitsudomi T, Saji H, Takamochi K, Kudo Y, Hattori A, Mimae T, Aokage K, Nishii T, Tsuboi M, Ikeda N. Feasibility and efficacy of salvage lung resection after definitive chemoradiation therapy for Stage III non-small-cell lung cancer. Interact Cardiovasc Thorac Surg. 23(6):895-901, 2016.12

雑誌論文（和文）

1. 坂井貴志、青景圭樹、三好智裕、松原伸晃、石井源一郎、関原圭吾、菱田智之、吉田純司、坪井正博.　縦隔原発非セミノーマ胚細胞腫瘍に対する化学療法後残存腫瘍切除術の治療成績とその予後の検討.　日本呼吸器外科学会.　31巻1号.　2016.

 2015年

1. 後藤真輝、坪井正博. 肺がん患者の治療とケア最前線肺がんの基礎知識.　がん看護9-10月号別冊.  第20巻第6号.
2. Omori T, Tajiri M, Baba T, Ogura T, Iwasawa T, Okudela K, Takemura T, Oba MS, Maehara T, Nakayama H, Tsuboi M, Masuda M. Pulmonary Resection for Lung Cancer in Patients With Idiopathic Interstitial Pneumonia. Ann Thorac Surg, 100(3):954-60,2015
3. Matsumura Y, Umemura S, Ishii G, Tsuta K, Matsumoto S, Aokage K, Hishida T, Yoshida J, Ohe Y, Suzuki H, Ochiai A, Goto K, Nagai K, Tsuchihara K. Expression profiling of receptor tyrosine kinases in high-grade neuroendocrine carcinoma of the lung: a comparative analysis with adenocarcinoma and squamous cell carcinoma. J Cancer Res Clin Oncol, 141(12):2159-70, 2015
4. Suzuki S, Ishii G, Matsuwaki R, Neri S, Hashimoto H, Yamauchi C, Aokage K, Hishida T, Yoshida J, Kohno M, Nagai K, Ochiai A. Ezrin-expressing lung adenocarcinoma cells and podoplanin-positive fibroblasts form a malignant microenvironment. J Cancer Res Clin Oncol, 141(3):475-84, 2015
5. Kinoshita T, Yoshida J, Ishii G, Hishida T, Wada M, Aokage K, Nagai K. The availability of pre- and intraoperative evaluation of a solitary pulmonary nodule in breast cancer patients. Ann Thorac Cardiovasc Surg, 21(1):31-6, 2015

2014年

1. Matsumura Y, Hishida T, Shimada Y, Ishii G, Aokage K, Yoshida J, Nagai K, Impact of extratumoral lymphatic permeation on postoperative survival of non-small-cell lung cancer patients. J Thoracic Oncol. 2014 Mar;9(3):337-344.
2. Yamada E, Ishii G, Aramaki N, Aokage K, Hishida T, Yoshida J, Kojima M, Nagai K, Ochiai A, Tumor-size-based morpholoogical features of metastatic lymph node tumors from primary lung adenocarcinoma. Pathology International.2014; 64: 591-600.
3. Matsuwaki R, Ishii G, Zenke Y, Neri S, Aokage K, Hishida T, Yoshida J, Fujii S Kondo H, Goya T, Nagai K, Ochiai A, Immunophenotypc fwatures of metastatic lymph node tumors to predic recurrence in N2 lung squamous cell carcinoma. Cancer Science. 2014 Jul; 105: 905-911
4. Neri S, Yoshida J, Ishii G, Matsumura Y, Aokage K, Hishida T, Nagai K, Prognostic inpact of microscopoc vessel invasion and pleural invasion in non-small cell lung cancer. Ann Surg. 2014 Aug; 260(2): 383-388
5. Neri S, Ishii G, Aokage K, Hishida T ,Yoshida J, Nishimura M, Nagai, K, Multiple Perivascular Epithelioid Cell Tumors: Clear Cell Tumor of the Lung Accompanied by Angiomyolipoma of the Liver. Ann Thorac Cardiovasc Surg. 2014; 20: 453-456.

2013年

1. Ohtaki Y, Hishida T, Yoshida J, Ishii G, Kawase A, Aokage K, Nishimura M, Nagai K, The clinical outcome of non-small cell lung cancer patients with adjacent lobe invasion : the optimal classification according to the status of the interlobar pleura at the invasion point, European Journal of Cardio-Thoracic Surgery, 2013　Feb; 43(2):302-309.
2. Kawase A, Yoshida J, Miyaoka E, Asamura H, Fujii Y, Nakanishi Y, Eguchi K, M,Mori, Sawabata N, Okumur M, Yokoi K, Visceral pleural invasion classification in non-small-cell lung cancer on the 7th edition of the tymor, node, metastasis classification for lung cancer: validation analysis based on a large-scale nationwide database. JThorac Oncol. 2013. 8: 606-611.
3. Neri S, Ishii G, Aokage K, Hishida T, Yoshida J, Nishimura M, Nagai K, Multiple perivascular epithelioid cell Tumors: clear cell thmor if the lung accompanied by angiomyolipoma of the liver. Ann Thorac Cardiovasc Surg.2013. Apr;20:1-4
4. Kinoshita T, Ishii G, Hiraoka N, Hirayama S, Yamauchi C, Aokage K, Hishida T, Yoshida J, Nagai K,Forkhead box P3 regulatory T cells coexisting with cancer associated fibroblasts are correlated with a poor outcime in lung adenocarcinoma. Japanese Cancer Association. 2013 Apr. 104: 409-415.
5. Kinoshita T, Yoshida J, Ishii G, Aokage K, Hishida T, Nagai K, The differences of biological behavior based on　the clinicopathological data between resectable large-cell neuroendocrine carcinoma and small-cell lung　carcinoma. Clinical Lung Cancer. 2013.Sep; 14(5): 535-540.
6. Takuwa T, Yoshida J, Ono S, Hishida T, Nishimura M, Aokage K, Nagai K, Low-fat diet management　strategy for chyllothorax after pulmonary resection and lymph node dissection for primary lung cancer.　Genaral Thoracic Surgery. 2013. 146(3):571-574
7. Takahashi,A., Ishii,G., Kinoshita,T., Yoshida,T., Umemura,S., Hishida,T., Yoh,K., Niho,S., Goto,K.,Ohmatsu,H., Ohe,Y., Nagai,K., Ochiai,A., Identification of prognostic　immunophenotypic features in cancer stromal cells of high-grade neuroendocrine carcinomas of the lung. J Cancer Res Clin Oncol. 2013 Sep 7.[Epub ahead of print]
8. Kaseda,K., Ishii,G., Aokage,K., Takahashi,A., Kuwata,T., Hishida,T., Yoshida,J., Kohno,M., Nagai,K., Ochiai,A., Identification of intravascular tumor microenvironment features predicting the recurrence of pathological stage I lung adenocarcinoma. Cancer Sci. 2013 Sep;104(9):1262-9.
9. Ono,S., Ishii,G., Nagai,K., Takuwa,T., Yoshida,J., Nishimura,M., Hishida,T., Aokage,K., Fujii,S., Ikeda,N., Ochiai,A., Podoplanin-positive cancer-associated fibroblasts could have prognostic value independent of cancer cell phenotype in stage I lung squamous cell carcinoma: usefulness of combining analysis of both cancer cell phenotype and cancer-associated fibroblast　 phenotype. Chest. 2013 Apr;143(4):963-70.
10. Takahashi,Y., Ishii,G., Aokage,K., Hishida,T., Yoshida,J., Nagai,K., Distinctive histopathological features of lepidic growth predominant node-negative adenocarcinomas 3-5 cm in size. Lung Cancer. 2013 Feb;79(2):118-24.

2012年

1. Kawase A, Yoshida J, Ishii G, Nakao M, Aokage K, Hishida T, Nishimura M, Nagai K, Differences between squamous cell carcinoma and adenocarcinoma of thelung: Are adenocarcinoma and squamous cell carcinoma prognostically equal? J J C O, 2012 Mar, 42(3): 189-195.
2. Nakao M, Hishida T, Ishii G, Yoshida J, Nishimura M, Nagai K, Malignant granular cell tumor of the posterior mediastinum with dissemination, Asian Cardiovasc Thorac Annals, 2012, 20(1): 71-73.
3. Shimada Y, Niho S, Ishii G, Hishida T, Yoshida J, Nishimura M,YohK, Goto K, Ohmatsu H, Ohe Y, Nagai K, Clinical features of unressectable high-grade lung neuroendocrine carcinoma diagnosed using biopsy specimens, Lung Cancer, 2012 Apr, 75(3): 368-373.
4. Matsumura Y, Ishii G, Aokage K, Kuwata T, Hishida T, Yoshida J, Nishimura M, Nagai K, Ochiai A, Morphophenotypic characteristics of intralymphatic cancer and stromal cells susceptible to lymphogenic metastasis, Cancer　Science, 2012 Jul, 103(7): 1342-1347.
5. Takuwa T, Ishii G, Nagai K, Yoshida J, Nishimura M, Hishida T, Neri S, Hasegawa S, Ochiai A, Characteristic immunophenotype of solid subtype component in lung adenocarcinoma, Annals of Surgical Oncology, 2012 Nov, 19:3943-3952.
6. Neri S, Ishii G, Taira T, Hishida T, Yoshida J, Nishimura M, Nagai K, Ochiai A, Recruitment of podoplanin positive cancer-associated fibroblasts in metastatic lymph nodes predicts poor prognosis in pathological N2 stage 3 lung adenocarcinoma, Annals of Surgical Oncology, 2012 19:3953-3962.
7. Maeda R, Ishii G, Itoh M, Hishida T, Yoshida J, Nishimura M, Haga H, Nagai K, Achiai A, Number of circulating endothelial progenitor cells and intratumoral microvessel density in non-small cell lung cancer patients: differences in angiogenic status between adenocarcinoma histologic subtypes, J Thorac Oncol, 2012 Mar,7(3): 503-511.
8. Maeda R, Yoshida J, Ishii G, Hishida T, Nishimura M, Nagai K, Influence of cigarette smoking on survival and tumor invasiveness in clinical stage IA lung adenocarcinoma, Ann Thorac Surg. 2012 May, 93(5): 1626-1632.
9. Nakao M, Yoshida J, Goto K, Ishii G, Kawase A, Aokage K, Hishida T, Nishimura M, Nagai K, Long-term outcomes of 50 cases of limited-resection trial for pulmonary ground-glass opacity nodules, J Thorac Oncol, 2012 Oct, 7(10): 1563-1566.
10. 10. MatsumuraY, Hishida T, Yoshida J, Aokage K, Ishii G, Nagai K, Reasonable extent of lymph node dissection in intentional segmentectomy for small-sized peripherak non-small cell lung cancer. J Thorac Oncol. 2012, 7(11): 1691-1697.
11. Kinoshita T, Yoshida J, Ishii G, Aokage K, Hishida T, Nagai K. Pulmonary metastasis from encapsulated cervical ectopic type a thymoma. Ann Thorac Surg 94(6): e141-142, 2012
12. Shimada Y, Yoshida J, Hishida T, Nishimura M, Ishii G, Nagai K. Predictive factors of pathologically proven noninvasive tumor characteristics in T1aN0M0 peripheral non-small cell lung cancer. Chest141(4): 1003-1009, 2012
13. 13. Kinoshita T, Ishii G, Matsumura Y, Shiozawa T, Aokage K, Hishida T, Yoshida J, Nagai K, The recurrence of malignant pleural mesothelioma 14 years after extrapleural pneumonectomy:Possible histological transformation。Pathology International.　2012,62：754-757.