研究について

研修・研究に関するお問い合わせ

国立がん研究センター東病院　循環器科　科長：田尻　和子
メールアドレス：＜ktajiri●east.ncc.go.jp＞

当科では、当院で腫瘍循環器の臨床や研究を学ぶレジデントや、他施設で所属しながら当院で研究を行う外来研究員を受け入れています。ご興味がおありの方はお気軽にご連絡ください。

研究内容

準備中

業績

雑誌論文(英文)

2023年度

1. Okabe Y, Murakoshi N, Kurebayashi N, Inoue H, Ito Y, Murayama T, Miyoshi C, Funato H, Ishii K, Xu D, Tajiri K, Qin R, Aonuma K, Murakata Y, Song Z, Wakana S, Yokoyama U, Sakurai T, Aonuma K, Ieda M, Yanagisawa M. An inherited life-threatening arrhythmia model established by screening randomly mutagenized mice. Proc Natl Acad Sci U S A. 2024 121(17):e2218204121.
2. Inoue K, Machino-Ohtsuka T, Nakazawa, Iida N, Sasamura R, Bando H, Chiba S, Tasaka N, Ishizu T, Murakoshi N, Xu D, Sekine I, Tajiri K. Early Detection and Prediction of Anthracycline-Induced Cardiotoxicity: A Prospective Cohort Study. Circ J. 2024 Mar 8. doi:10. 1253/circj. CJ-24-0065. Online ahead of print.
3. Osawa T, Tajiri K, Hoshi T, Ieda M, Ishizu T. Successful Treatment of Malignant Lymphoma Following Transcatheter Aortic Valve Replacement: A Case Report. Intern Med. 2024 Feb 1. doi:10.2169/internalmedicine. 3065-23. Online ahead of print.

4. Shoji M, Yamashita Y, Ishii M, Inoue H, Kato H, Fujita S, Matsui K, Tajiri K, Nameki M, Muraoka N, Nonaka A, Sugino H, Kono M, Oka T, Sueta D, Komuro I, Tsujita K; J-Khorana Registry Investigators. A Predictive Model for Cancer-Associated Thrombosis in Japanese Cancer Patients: Findings from the J-Khorana Registry. TH Open. 2024 8(1):e9-e18. 

5. Ishizuka Y, Tajiri K. The Need for Next-generation Anticoagulation Therapies for Cancer-associated Venous Thromboembolism. Intern Med. 2023 doi:10. 2169/internalmedicine. 3012-23. Online ahead of print.

6. Shibutani Y, Tajiri K, Suzuki S, Enokida T, Sagara A, Okano S, Fujisawa T, Sato F, Yumoto T, Sano M, Kawasaki T, Tahara M. Association between baseline blood pressure and the incidence of lenvatinib-induced hypertension in patients with thyroid cancer. Cancer Med. 2023 12(22):20773-20782. 

7. Osawa T, Tajiri K, Ieda M, Ishizu T. Clinical outcomes of takotsubo syndrome in patients with cancer: a systematic review and meta-analysis. Front Cardiovasc Med. 2023 10時12分44808.

8. Osawa T, Tajiri K. Neoplastic Cardiac Tamponade. Intern Med. 2023 62(17):2447-2448. 

9. Nagai T, Inomata T, Kohno T, Sato T, Tada A, Kubo T, Nakamura K, Oyama-Manabe N, Ikeda Y, Fujino T, Asaumi Y, Okumura T, Yano T, Tajiri K, Matsuura H, Baba Y, Sunami H, Tsujinaga S, Ota Y, Ohta-Ogo K, Ishikawa Y, Matama H, Nagano N, Sato K, Yasuda K, Sakata Y, Kuwahara K, Minamino T, Ono M, Anzai T; Japanese Circulation Society Joint Working Group. JCS 2023 Guideline on the Diagnosis and Treatment of Myocarditis. Circ J. 2023 87(5):674-754. 

2022年度

1. Murakata Y, Yamagami F, Murakoshi N, Xu D, Song Z, Li S, Okabe Y, Aonuma K, Yuan Z, Mori H, Aonuma K, Tajiri K, Ieda M. Electrical, structural, and autonomic atrial remodeling underlies atrial fibrillation in inflammatory atrial cardiomyopathy. Front Cardiovasc Med. 2023 9時10分75358.

2. Tajiri K, Suehara Y, Suzuki T, Sekine I. Clonal heamatopoiesis and associated cardiovascular diseases. Jpn J Clin Oncol. 2023 53(3):187-194.

3. Negishi T, Thavendiranathan P, Penicka M, Lemieux J, Murbraech K, Miyazaki S, Shirazi M, Santoro C, Cho GY, Popescu BA, Kosmala W, Costello B, la Gerche A, Mottram P, Thomas L, Seldrum S, Hristova K, Bansal M, Kurosawa K, Fukuda N, Yamada H, Izumo M, Tajiri K, Sinski M, Vinereanu D, Shkolnik E, Banchs J, Kutty S, Negishi K, Marwick TH. Cardioprotection Using Strain-Guided Management of Potentially Cardiotoxic Cancer Therapy: 3-Year Results of the SUCCOUR Trial. JACC Cardiovasc Imaging. 2023 16(3):269-278.

4. Inoue K, Tajiri K, Xu D, Murakoshi N, Ieda M. ASO Visual Abstract: Risk Factors and In-Hospital Outcomes of Perioperative Atrial Fibrillation in Patients with Cancer: A Meta-analysis. Ann Surg Oncol. 2023 30(2):723-724.

5. Tajiri K, Inoue K. ASO Author Reflections: Perioperative Atrial Fibrillation in Patients Undergoing Cancer Surgery. Ann Surg Oncol. 2023 30(2):722.

6. Inoue K, Tajiri K, Xu D, Murakoshi N, Ieda M. Risk Factors and In-Hospital Outcomes of Perioperative Atrial Fibrillation for Patients with Cancer: A Meta-Analysis. Ann Surg Oncol. 2023 30(2):711-721.

7. Aonuma K, Xu D, Murakoshi N, Tajiri K, Okabe Y, Yuan Z, Li S, Murakata Y, Tominaga K, Nogami A, Aonuma K, Ieda M, Isoda H. Novel preventive effect of isorhamnetin on electrical and structural remodeling in atrial fibrillation. Clin Sci (Lond). 2022 136(24):1831-1849.

8. Nowatzke J, Guedeney P, Palaskas N, Lehmann L, Ederhy S, Zhu H, Cautela J, Francis S, Courand PY, Deswal A, Ewer SM, Aras M, Arangalage D, Ghafourian K, Fenioux C, Finke D, Peretto G, Zaha V, Itzhaki Ben Zadok O, Tajiri K, Akhter N, Levenson J, Baldassarre L, Power J, Huang S, Collet JP, Moslehi J, Salem JE; International ICI-myocarditis registry contributors. Coronary artery disease and revascularization associated with immune checkpoint blocker myocarditis: Report from an international registry. Eur J Cancer. 2022 177:197-205.

9. Yuan Z, Murakoshi N, Xu D, Tajiri K, Okabe Y, Aonuma K, Murakata Y, Li S, Song Z, Shimoda Y, Mori H, Aonuma K, Ieda M. Identification of potential dilated cardiomyopathy-related targets by meta-analysis and co-expression analysis of human RNA-sequencing datasets. Life Sci. 2022 36時12分0807. 

10. Nakagomi Y, Tajiri K, Shimada S, Li S, Inoue K, Murakata Y, Murata M, Sakai S, Sato K, Ieda M. Immune Checkpoint Inhibitor-Related Myositis Overlapping With Myocarditis: An Institutional Case Series and a Systematic Review of Literature. Front Pharmacol. 2022 13:884776.

11. Shimoda Y, Murakoshi N, Mori H, Xu D, Tajiri K, Hemmi Y, Sato I, Noguchi M, Nakamura Y, Hayashi Y, Ieda M. Generation of a human induced pluripotent stem cell line derived from a patient with dilated cardiomyopathy carrying LMNA nonsense mutation. Stem Cell Res. 2022 62:102793.

12. Yamamoto M, Tajiri K, Ayuzawa S, Ieda M. Pathological findings of clinically suspected myocarditis temporally associated with COVID-19 vaccination. Eur J Heart Fail. 2022 24(6):1132-1138.

13. Inoue K, Tajiri K. Galectin-3 as an Arrhythmogenic Predictive Marker for Heart Failure. Intern Med. 2022 61(7):933-934.

14. Tajiri K, Sekine I. Atherosclerotic cardiovascular events associated with immune checkpoint inhibitors in cancer patients. Jpn J Clin Oncol. 2022 52(7):659-664.

15. Murakata Y, Tajiri K. A Diverse Range of Cardiac Adverse Events Associated with Immune Checkpoint Inhibitor Therapy. Intern Med. 2022 61(14):2099-2100.

16. Iida N, Tajiri K, Ishizu T, Sasamura-Koshizuka R, Nakajima H, Kawamatsu N, Sato K, Yamamoto M, Machino-Ohtsuka T, Bando H, Sekine I, Kawakami Y, Ieda M. Echocardiography image quality of global longitudinal strain in cardio-oncology: a prospective real-world investigation. J Echocardiogr. 2022 20(3):159-165.

17. Kosuge H, Nakamura M, Oyane A, Tajiri K, Murakoshi N, Sakai S, Sato A, Taninaka A, Chikamori T, Shigekawa H, Aonuma K. Potential of Gold Nanoparticles for Noninvasive Imaging and Therapy for Vascular Inflammation. Mol Imaging Biol. 2022 24(5):692-699.

雑誌論文（和文）

2023年度

1. 田尻和子. 免疫チェックポイント阻害薬関連心筋炎の病態と機序. 日本臨床. 2024 in press
2. 柴山さゆり, 田尻和子. 分子標的薬による心血管毒性の心エコー診断. 心エコー図. in press
3. 田尻和子. 岩本論文に対するEditorial Comment. 心臓 2023;55(12):1174-1175.

4. 田尻 和子. 診断と治療 がん治療関連心機能障害(CTRCD). 日本臨床. 2023 81(11):1712-1720.

5. 村田桃子, 田尻和子. 腫瘍循環器のガイドライン─がん関連血栓症. 心エコー図. 2023 24(9):870-875.

6. 石塚 祐紀, 田尻 和子. 森論文に対するEditorial Comment. 心臓. 2023 55(7):681-682.

7. 石塚祐紀, 田尻和子. 免疫チェックポイント阻害薬関連心筋炎のマネジメント. BIO Clinica. 2023 38(5):

   73-77.

2022年度

1. 田尻和子, 家田真樹. 心筋梗塞後の抗炎症治療. 循環器内科. 2023 93(3):326-330.

2. 中込祐紀, 田尻和子. 免疫チェックポイント阻害薬関連心筋炎. カレントテラピー. 2023 41(2):174.

3. 井上 慶子, 田尻 和子. トラスツズマブ心毒性の分子メカニズム. Heart View 2022 26(10), 978-984

4. 田尻和子, Onco-Cardiologyにおける心筋炎. 医学のあゆみ. 2022 282(11):998-1002

5. 田尻和子. 岡田論文に対するEditorial Comment. 心臓. 2022 54(8):952-953

6. 田尻和子. Masters Summit on PE/DVT in Tsukuba「婦人科がん治療におけるOnco-Cardiology」. 県母医報 2022 261-263:20-23

7. 田尻 和子, 中澤 陽子. 藤井論文に対するEditorial Comment. 心臓. 2022 54(7):821-822

8. 田尻和子. 免疫チェックポイント阻害薬関連心筋炎の病態と管理. Precision Medicin. 2022 5(8):754-758

書籍（和文）

2023年度

1. 腫瘍循環器領域 薬物療法ポケットブック。2023 in press
2. 腫瘍循環器診療 実践トレーニング。日本腫瘍循環器学会, メジカルビュー社, 2024

1. 今日の治療指針 2024年版―私はこう治療している。第6章　循環器疾患（担当：『がんに伴う循環器疾患』）, 医学書院, 2024

2022年度

1. がん免疫療法ガイドライン第3版,―日本臨床腫瘍学会編,―金原出版,― 2023

2. 2023年改訂版 心筋炎の診断・治療に関するガイドライン, 日本循環器学会, 2023