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研究について

新しい治療法の開発は当センターの重要な社会的使命であり、新治療法の臨床試験に積極的に取り組んでいます。また、患者さんから採取した検体（組織、血液）は、患者さんのご了解を得て、癌の本態解明や治療法開発のための研究に利用させていただいています。

現在当科で行っている臨床研究

JCOG0802/WJOG4607L肺野末梢小型非小細胞肺癌に対する肺葉切除と縮小切除(区域切除)の第III相試験
JCOG1413：臨床病期I/II期非小細胞肺癌に対する選択的リンパ節郭清の治療的意義に関するランダム化比較試験
胸部腫瘍の臨床病理学的な特性と治療の効果・安全性等に関する研究
肺癌登録合同委員会：胸腺上皮性腫瘍の前方視的データベース研究
JCOG1708：特発性肺線維症（IPF）合併臨床病期I期非小細胞肺癌に対する肺縮小手術に関するランダム化比較第III相試験
原発性肺癌の術前画像所見に基づく病理所見・予後の予測に関する観察研究
JCOG1807C: 肺尖部胸壁浸潤癌に対する化学放射線療法後の術前後デュルバルマブもしくはデュルバルマブ維持療法を併用した集学的治療に関する単群検証的試験
JCOG1909：肺葉切除高リスク臨床病期IA期非小細胞肺癌に対する区域切除と楔状切除のランダム化比較試験
JCOG1906：胸部薄切CT所見に基づく早期肺癌に対する経過観察の単群検証的試験
JCOG1916：病理学的N2非小細胞肺癌に対する術後放射線治療に関するランダム化比較第III相試験
2021年に外科治療を施行された肺癌症例のデータベース研究: 肺癌登録合同委員会第11次事業
転移性肺腫瘍に対する外科切除後の予後に関する観察研究
肺腫瘍、胸腺腫瘍患者の臨床検体（組織や血液など）を用いたゲノムプロファイリングに関する研究
JCOG2012：病理病期II-IIIA期非小細胞肺癌に対する術後サーベイランスに関するランダム化比較試験
NCDを用いた本邦における悪性胸膜中皮腫に対する根治術の有用性および予後予測因子の検討: 肺癌登録合同委員会　第12次事業
JCOG2109：80歳以上の高齢者肺野末梢小型非小細胞肺癌における区域切除 vs. 楔状切除のランダム化比較試験
原発性胸部悪性腫瘍に対する外科切除の長期的記録を用いた周術期成績と術後予後の観察研究
CLDN6陽性非小細胞肺癌に関する観察研究
JCOG2103：画像上診断困難な胸膜播種を有する臨床病期IVA期（cT1-2bN0-1M1a）非小細胞肺癌に対する原発巣切除追加の治療的意義を検証するランダム化比較第III相試験
3Dセンサーを使用した、見守り支援サービスシステムの共同開発を目的とした実用性の研究
AI技術を用いた透視画像の疑似3D化に関する多機関共同観察研究
JCOG2108：非小細胞肺癌術後オリゴ再発に対する全身治療後の維持療法と局所療法を比較するランダム化比較第III相試験
肺がん手術が患者さんの運動耐容能に与える影響の調査(介入研究)
2017年に外科治療を施行された肺癌症例のデータベース研究（肺癌登録合同委員会第10次事業）
JCOG2217：胸部薄切 CT 上すりガラス成分を伴う充実成分優位な非小細胞肺癌（＞2-3 cm）に対する肺葉切除と区域切除のランダム化比較試験
JCOG2317: 切除可能な臨床病期II-III期非小細胞肺癌に対する術前療法後手術と手術先行療法に関するランダム化比較第III相試験

2024年度業績（2024年4月～2025年3月）

雑誌論文（欧文）

Watanabe SI, Yotsukura M, Miyoshi T, Hattori A, Isaka T, Maniwa T, Isaka M, Yoshioka H, Endo M, Mimae T, Tsutani Y, Nakagawa K, Aokage K; Lung Cancer Surgical Study Group (LCSSG) of the Japan Clinical Oncology Group (JCOG). Updated review of perioperative treatment for non-small-cell lung cancer in the new era of immune checkpoint inhibitors: past, present, and future. Jpn J Clin Oncol. 2024 Dec 7;54(12):1244-1253. PMID: 39163130. DOI: 10.1093/jjco/hyae106.
Yotsukura M, Yoshida Y, Nakagawa K, Watanabe SI.　 Prognostic Indicator for Pleural Mesothelioma. Ann Thorac Surg Short Rep. 2024 Jun 6;2(4):597-602. PMID: 39790586. PMCID: PMC11708647. DOI: 10.1016/j.atssr.2024.05.011. eCollection 2024 Dec.

共著者論文

Takamochi K, Suzuki K, Okada M, Niho S, Ishikura S, Oyamada S, Yamaguchi T, Horio H, Ikeda N, Tanaka F, Shiono S, Haruki T, Yoshino I, Ito H, Uramoto H, Okumura N, Iwata H, Saji H, Fujiwara T, Funai K, Ueno T, Sugio K, Tsuboi M; Advanced Clinical Trial Chest Surgery Group ACTG. CRES3T: A single-arm confirmatory trial of S-1 plus cisplatin with concurrent radical-dose radiotherapy followed by surgery for superior sulcus tumors. Lung Cancer. 2025 Mar 19:202:108506. PMID: 40120334 DOI: 10.1016/j.lungcan.2025.108506. Online ahead of print.　
Torasawa M, Yoshida T, Shiraishi K, Yagishita S, Ono H, Uehara Y, Miyakoshi J, Tateishi A, Igawa YS, Higashiyama RI, Mochizuki A, Masuda K, Matsumoto Y, Shinno Y, Okuma Y, Goto Y, Horinouchi H, Hamamoto R, Yamamoto N, Watanabe SI, Yatabe Y, Takahashi K, Kohno T, Ohe Y. Implications of EGFR expression on EGFR signaling dependency and adaptive immunity against EGFR-mutated lung adenocarcinoma. Lung Cancer. 2025 Mar 11:202:108494. doi: 10.1016/j.lungcan.2025.108494. Online ahead of print. PMID: 40088580 DOI: 10.1016/j.lungcan.2025.108494.
Kayawake H, Okami J, Shintani Y, Ito H, Ohtsuka T, Toyooka S, Mori T, Watanabe SI, Asamura H, Chida M, Endo S, Kadokura M, Nakanishi R, Miyaoka E, Yoshino I, Date H; Japanese Joint Committee of Lung Cancer Registry. Predictors of nodal upstaging in clinical N1 nonsmall cell lung cancer. Jpn J Clin Oncol. 2025 Mar 5;55(3):283-289. PMID: 39537201. DOI: 10.1093/jjco/hyae161.
Nakagawa K, Watanabe SI, Wakabayashi M, Sekino Y. A Response to Letter to the Editor: "Considerations on Genetics and Treatment Factors in NSCLC Segmentectomy Outcomes". J Thorac Oncol. 2025 Feb;20(2):e27-e28. PMID: 39914927. DOI: 10.1016/j.jtho.2024.11.030.
Nakagawa K, Watanabe SI, Wakabayashi M, Sekino Y. A Response to the Letter to the Editor: "Sites of Primary Tumors as Crucial Points When Conducting Segmentectomy for NSCLC". J Thorac Oncol. 2025 Feb;20(2):e24-e25. PMID: 39914925. DOI: 10.1016/j.jtho.2024.11.031 .
Nakagawa K, Watanabe SI, Wakabayashi M, Sekino Y. A Response to Letter to the Editor: "Refining Risk Stratification for Locoregional Relapse in Clinical Stage IA Small-Sized Peripheral NSCLC After Segmentectomy". J Thorac Oncol. 2025 Feb;20(2):e22-e23. PMID: 39914923. DOI: 10.1016/j.jtho.2024.11.029 .
Ikeda S, Ogura T, Miyaoka E, Sekine I, Shukuya T, Takayama K, Inoue A, Okamoto I, Seike M, Takahashi K, Yamamoto N, Yotsukura M, Watanabe SI, Shintani Y. Survival benefit and potential markers of chemotherapy for elderly and poor performance status patients with advanced non-small cell lung cancer: Results from the Japanese Joint Committee of lung cancer registry database. Lung Cancer. 2025 Feb:200:108102. PMID: 39924255. DOI: 10.1016/j.lungcan.2025.108102.
Kosuge A, Yoshida Y, Yotsukura M, Watanabe SI. En bloc upper and lower lobe bisegmentectomy for non-small-cell lung cancer invading the fissure. Jpn J Clin Oncol. 2025 Feb 4;55(2):194-197. PMID: 39902921. DOI: 10.1093/jjco/hyae140.
Sekino Y, Hishida T, Yoshioka H, Wakabayashi M, Mitome N, Shiono S, Kenmotsu H, Nosaki K, Aokage K, Horinouchi H, Fukuda H, Ohe Y, Watanabe SI; Lung Cancer Surgical Study Group (LCSSG) and the Lung Cancer Study Group (LCSG) of the Japan Clinical Oncology Group (JCOG). Protocol summary of a randomized phase III study: comparing systemic therapy with and without debulking surgery (primary tumour resection) for clinical stage IVA (cT1-2bN0-1M1a) non-small cell lung cancer with radiologically undetermined pleural dissemination JCOG2103 (DEBULK-LUNG). Jpn J Clin Oncol. 2025 Feb 4;55(2):176-182. PMID: 39444315. DOI: 10.1093/jjco/hyae143.
Nakagawa K, Watanabe SI, Wakabayashi M, Yotsukura M, Mimae T, Hattori A, Miyoshi T, Isaka M, Endo M, Yoshioka H, Tsutani Y, Isaka T, Maniwa T, Nakajima R, Suzuki K, Aokage K, Saji H, Tsuboi M, Okada M, Asamura H, Sekino Y, Nakamura K, Fukuda H. Risk Factors for Locoregional Relapse After Segmentectomy: Supplementary Analysis of the JCOG0802/WJOG4607L Trial. J Thorac Oncol. 2025 Feb;20(2):157-166. PMID: 39327855. DOI: 10.1111/his.15328. Epub 2024 Oct 10.
Kojima N, Nishino S, Sasahara Y, Taki T, Imada H, Miyoshi T, Watanabe SI, Ishii G, Yatabe Y, Mori T, Yoshida A. Inflammatory spindle cell PEComa of the lung with YAP1::TFE3 fusion: a report of two cases and a potential relationship with clear cell stromal tumour. Histopathology. 2025 Feb;86(3):365-372. doi: 10.1111/his.15328. Epub 2024 Sep 26.
Masuda K, Yoshida T, Motoi N, Shinno Y, Matsumoto Y, Okuma Y, Goto Y, Horinouchi H, Yamamoto N, Watanabe SI, Hoshino T, Yatabe Y, Ohe Y. Schlafen 11 Expression in Patients With Small Cell Lung Cancer and Its Association With Clinical Outcomes. Thorac Cancer. 2025 Jan;16(1):e15529. PMID: 39809728. PMCID: PMC11732703. DOI: 10.1111/1759-7714.15529 .
Yamamoto G, Tanaka K, Kamata R, Saito H, Yamamori-Morita T, Nakao T, Liu J, Mori S, Yagishita S, Hamada A, Shinno Y, Yoshida T, Horinouchi H, Ohe Y, Watanabe SI, Yatabe Y, Kitai H, Konno S, Kobayashi SS, Ohashi A. WEE1 confers resistance to KRASG12C inhibitors in non-small cell lung cancer. Cancer Lett. 2024 Dec 24:611:217414. PMID: 39725152, DOI: 10.1016/j.canlet.2024.217414.　Online ahead of print.
Ohashi K, Nishito Y, Fukuda H, Sadahiro R, Yoshida Y, Watanabe SI, Motoi N, Sonobe Y, Mizuno H, Tsunoda H, Tatsumi K, Suzuki T, Ochiai A, Aoki K.　 Author Correction: Neutrophil-to-lymphocyte ratio is a prognostic factor reflecting immune condition of tumor microenvironment in squamous cell lung cancer. Sci Rep. 2024 Dec 13;14(1):30457. PMID: 39672904. PMCID: PMC11645401 DOI: 10.1038/s41598-024-81463-2.
Miyoshi T, Aokage K, Watanabe SI, Ito H, Sakakura N, Mun M, Yamashita M, Ohde Y, Aoki T, Nishio W, Taguri M, Tsuboi M.　 The effect of epidermal growth factor receptor mutation on adjuvant chemotherapy with tegafur/uracil for patients with completely resected, non-lymph node metastatic non-small cell lung cancer (> 2 cm): a multicenter, retrospective, observational study as exploratory analysis of the CSPOR-LC03 study. Jpn J Clin Oncol. 2024 Nov 2;54(11):1185-1193.　PMID: 39255996. PMCID: PMC11532619. DOI: 10.1093/jjco/hyae073.
Nakagawa K, Yotsukura M, Mimae T, Hattori A, Miyoshi T, Isaka M, Endo M, Tsutani Y, Isaka T, Maniwa T, Nakajima R, Yoshioka H, Takei H, Aokage K, Watanabe SI. The Lung Cancer Surgical Study Group of the Japan Clinical Oncology Group: outstanding contribution and entering a new phase. Jpn J Clin Oncol. 2024 Dec 7;54(12):1237-1243. doi: 10.1093/jjco/hyae100.　 PMID: 39158320 DOI: 10.1093/jjco/hyae100.
Kayawake H, Okami J, Shintani Y, Ito H, Ohtsuka T, Toyooka S, Mori T, Watanabe SI, Asamura H, Chida M, Endo S, Kadokura M, Nakanishi R, Miyaoka E, Yoshino I, Date H; Japanese Joint Committee of Lung Cancer Registry.　 Predictors of nodal upstaging in clinical N1 nonsmall cell lung cancer. Jpn J Clin Oncol. 2024 Nov 13:hyae161. PMID: 39537201 DOI: 10.1093/jjco/hyae161. Online ahead of print.　
Blechter B, Hsiung CA, Wang X, Zhang H, Seow WJ, Shi J, Chatterjee N, Kim HN, Wong MP, Hong YC, Wong JY, Dai J, Hosgood HD, Wang Z, Chang IS, Choi J, Wang J, Song M, Hu W, Zheng W, Kim JH, Zhou B, Albanes D, Shin MH, Chung LP, An SJ, Zheng H, Yatabe Y, Zhang XC, Kim YT, Shu XO, Kim YC, Vermeulen RCH, Bassig BA, Chang J, Man Ho JC, Ji BT, Kubo M, Daigo Y, Momozawa Y, Kamatani Y, Honda T, Kunitoh H, Watanabe SI, Miyagi Y, Nakayama H, Matsumoto S, Tsuboi M, Goto K, Yin Z, Takahashi A, Goto A, Minamiya Y, Shimizu K, Tanaka K, Wu T, Wei F, Su J, Kim YH, Oh IJ, Fun Lee VH, Su WC, Chen YM, Chang GC, Chen KY, Huang MS, Lin HC, Seow A, Park JY, Kweon SS, Chen CJ, Gao YT, Wu C, Qian B, Lu D, Liu J, Jeon HS, Hsiao CF, Sung JS, Tsai YH, Jung YJ, Guo H, Hu Z, Chen TY, Burdett L, Yeager M, Hutchinson A, Berndt SI, Wu W, Wang J, Choi JE, Park KH, Sung SW, Liu L, Kang CH, Chen CH, Xu J, Guan P, Tan W, Wang CL, Loon Sihoe AD, Chen Y, Choi YY, Kim JS, Yoon HI, Cai Q, Park IK, Xu P, He Q, Chen CY, Wu J, Lim WY, Chen KC, Chan JKC, Li J, Chen H, Yu CJ, Jin L, Fraumeni JF Jr, Liu J, Landi MT, Yamaji T, Yang Y, Hicks B, Wyatt K, Li SA, Ma H, Song B, Wang Z, Cheng S, Li X, Ren Y, Iwasaki M, Zhu J, Jiang G, Fei K, Wu G, Chien LH, Tsai FY, Yu J, Stevens VL, Yang PC, Lin D, Chen K, Wu YL, Matsuo K, Rothman N, Shiraishi K, Shen H, Chanock SJ, Kohno T, Lan Q. Polygenic risk score and lung adenocarcinoma risk among never-smokers by EGFR mutation status-a brief report. J Thorac Oncol. 2024 Nov 22:S1556-0864(24)02482-1. PMID: 39581378. DOI: 10.1016/j.jtho.2024.11.019. Online ahead of print.
Blechter B, Wang X, Shi J, Shiraishi K, Choi J, Matsuo K, Chen TY, Dai J, Hung RJ, Chen K, Shu XO, Kim YT, Choudhury PP, Williams J, Landi MT, Lin D, Zheng W, Yin Z, Zhou B, Wang J, Seow WJ, Song L, Chang IS, Hu W, Chien LH, Cai Q, Hong YC, Kim HN, Wu YL, Wong MP, Richardson BD, Li S, Zhang T, Breeze C, Wang Z, Bassig BA, Kim JH, Albanes D, Wong JY, Shin MH, Chung LP, Yang Y, An SJ, Zheng H, Yatabe Y, Zhang XC, Kim YC, Caporaso NE, Chang J, Man Ho JC, Kubo M, Daigo Y, Song M, Momozawa Y, Kamatani Y, Kobayashi M, Okubo K, Honda T, Hosgood HD, Kunitoh H, Watanabe SI, Miyagi Y, Nakayama H, Matsumoto S, Horinouchi H, Tsuboi M, Hamamoto R, Goto K, Ohe Y, Takahashi A, Goto A, Minamiya Y, Hara M, Nishida Y, Takeuchi K, Wakai K, Matsuda K, Murakami Y, Shimizu K, Suzuki H, Saito M, Ohtaki Y, Tanaka K, Wu T, Wei F, Dai H, Machiela MJ, Su J, Kim YH, Oh IJ, Fun Lee VH, Chang GC, Tsai YH, Che KY, Huang MS, Su WC, Chen YM, Seow A, Park JY, Kweon SS, Chen KC, Gao YT, Qian B, Wu C, Lu D, Liu J, Schwartz AG, Houlston R, Spitz MR, Gorlov IP, Wu X, Yang P, Lam S, Tardon A, Chen C, Bojesen SE, Johansson M, Risch A, Bickeböller H, Ji BT, Wichmann HE, Christiani DC, Rennert G, Arnold S, Brennan P, McKay J, Field JK, Davies MPA, Shete SS, Marchand LL, Liu G, Andrew A, Kiemeney LA, Zienolddiny-Narui S, Grankvist K, Johansson M, Cox A, Taylor F, Yuan JM, Lazarus P, Schabath MB, Aldrich MC, Jeon HS, Jiang SS, Sung JS, Chen CH, Hsiao CF, Jung YJ, Guo H, Hu Z, Burdett L, Yeager M, Hutchinson A, Hicks B, Liu J, Zhu B, Berndt SI, Wu W, Wang J, Li Y, Choi JE, Park KH, Sung SW, Liu L, Kang CH, Wang WC, Xu J, Guan P, Tan W, Yu CJ, Yang G, Sihoe ADL, Chen Y, Choi YY, Kim JS, Yoon HI, Park IK, Xu P, He Q, Wang CL, Hung HH, Vermeulen RCH, Cheng I, Wu J, Lim WY, Tsai FY, Chan JKC, Li J, Chen H, Lin HC, Jin L, Liu J, awada N, Yamaji T, Wyatt K, Li SA, Ma H, Zhu M, Wang Z, Cheng S, Li X, Ren Y, Chao A, Iwasaki M, Zhu J, Jiang G, Fei K, Wu G, Chen CY, Chen CJ, Yang PC, Yu J, Stevens VL, Fraumeni JF, Chatterjee N, Gorlova OY, Amos CI, Shen H, Hsiung CA, Chanock SJ, Rothman N, Kohno T, Lan Q, Zhang H. Stratifying Lung Adenocarcinoma Risk with Multi-ancestry Polygenic Risk Scores in East Asian Never-Smokers. medRxiv [Preprint]. 2024 Nov 6:2024.06.26.24309127. PMID: 38978671. PMCID: PMC11230324. DOI: 10.1101/2024.06.26.24309127.
Nakagawa K, Watanabe SI, Wakabayashi M, Yotsukura M, Mimae T, Hattori A, Miyoshi T, Isaka M, Endo M, Yoshioka H, Tsutani Y, Isaka T, Maniwa T, Nakajima R, Suzuki K, Aokage K, Saji H, Tsuboi M, Okada M, Asamura H, Sekino Y, Nakamura K, Fukuda H. Risk factors for locoregional relapse after segmentectomy: Supplementary analysis of the JCOG0802/WJOG4607L trial. J Thorac Oncol. 2024 Oct 10:S1556-0864(24)02376-1. PMID: 39395662 DOI: 10.1016/j.jtho.2024.10.002. Online ahead of print.
Sekino Y, Hishida T, Yoshioka H, Wakabayashi M, Mitome N, Shiono S, Kenmotsu H, Nosaki K, Aokage K, Horinouchi H, Fukuda H, Ohe Y, Watanabe SI; Lung Cancer Surgical Study Group (LCSSG) and the Lung Cancer Study Group (LCSG) of the Japan Clinical Oncology Group (JCOG). Protocol summary of a randomized phase III study: comparing systemic therapy with and without debulking surgery (primary tumour resection) for clinical stage IVA (cT1-2bN0-1M1a) non-small cell lung cancer with radiologically undetermined pleural dissemination JCOG2103 (DEBULK-LUNG). Jpn J Clin Oncol. 2024 Oct 23:hyae143. PMID: 39444315 DOI: 10.1093/jjco/hyae143. Online ahead of print.
Tane S, Okami J, Maniwa Y, Shintani Y, Ito H, Ohtsuka T, Toyooka S, Mori T, Watanabe SI, Chida M, Endo S, Nakanishi R, Kadokura M, Suzuki H, Miyaoka E, Yoshino I, Date H; Japanese Joint Committee of Lung Cancer Registry. Clinical outcomes of left upper segmentectomy vs. lobectomy for early non-small-cell lung cancer: a nationwide database study in Japan. Surg Today. 2024 Oct;54(10):1162-1172. PMID: 38635057 PMCID: PMC11413095 DOI: 10.1007/s00595-024-02844-8. Epub 2024 Apr 18.
Miyoshi T, Aokage K, Watanabe SI, Ito H, Sakakura N, Mun M, Yamashita M, Ohde Y, Aoki T, Nishio W, Taguri M, Tsuboi M. The effect of epidermal growth factor receptor mutation on adjuvant chemotherapy with tegafur/uracil for patients with completely resected, non-lymph node metastatic non-small cell lung cancer (> 2 cm): a multicenter, retrospective, observational study as exploratory analysis of the CSPOR-LC03 study. Jpn J Clin Oncol. 2024 Nov 2;54(11):1185-1193. doi: 10.1093/jjco/hyae073.　 PMID: 39255996 PMCID: PMC11532619 DOI: 10.1093/jjco/hyae073.
Kojima N, Nishino S, Sasahara Y, Taki T, Imada H, Miyoshi T, Watanabe SI, Ishii G, Yatabe Y, Mori T, Yoshida A. Inflammatory spindle cell PEComa of the lung with YAP1::TFE3 fusion: a report of two cases and a potential relationship with clear cell stromal tumour. Histopathology. 2024 Sep 26. PMID: 39327855 DOI: 10.1111/his.15328. Online ahead of print.
Asada K, Kaneko S, Takasawa K, Shiraishi K, Shinkai N, Shimada Y, Takahashi S, Machino H, Kobayashi K, Bolatkan A, Komatsu M, Yamada M, Miyake M, Watanabe H, Tateishi A, Mizuno T, Okubo Y, Mukai M, Yoshida T, Yoshida Y, Horinouchi H, Watanabe SI, Ohe Y, Yatabe Y, Kohno T, Hamamoto R. Multi-omics and clustering analyses reveal the mechanisms underlying unmet needs for patients with lung adenocarcinoma and identify potential therapeutic targets. Mol Cancer. 2024 Sep 2;23(1):182. PMID: 39218851 PMCID: PMC11367768 DOI: 10.1186/s12943-024-02093-w.
Fujiwara Y, Takahashi RU, Saito M, Umakoshi M, Shimada Y, Koyama K, Yatabe Y, Watanabe SI, Koyota S, Minamiya Y, Tahara H, Kono K, Shiraishi K, Kohno T, Goto A, Tsuchiya N. Oncofetal IGF2BP3-mediated control of microRNA structural diversity in the malignancy of early-stage lung adenocarcinoma. Proc Natl Acad Sci U S A. 2024 Sep 3;121(36):e2407016121. PMID: 39196622 PMCID: PMC11388381 (available on 2025-02-28) DOI: 10.1073/pnas.2407016121. Epub 2024 Aug 28.
Fujiwara W, Yotsukura M, Yoshida Y, Nakagawa K, Kashima J, Yatabe Y, Watanabe SI. Clinical and Pathologic Differences between Small-Cell Carcinoma and Large-Cell Neuroendocrine Carcinoma of the Lung. Comparative Study Ann Surg Oncol. 2024 Sep;31(9):5697-5705. PMID: 38811497. DOI: 10.1245/s10434-024-15505-4. Epub 2024 May 29.
Maniwa T, Okami J, Miyoshi T, Wakabayashi M, Yoshioka H, Mimae T, Endo M, Hattori A, Nakagawa K, Isaka T, Isaka M, Kita R, Sekino Y, Mitome N, Aokage K, Saji H, Nakajima R, Okada M, Tsuboi M, Asamura H, Fukuda H, Watanabe SI; West Japan Oncology Group and Japan Clinical Oncology Group. Lymph node dissection in small peripheral lung cancer: Supplemental analysis of JCOG0802/WJOG4607L. J Thorac Cardiovasc Surg. 2024 Sep;168(3):674-683.e1. doi: 10.1016/j.jtcvs.2023.11.023. Epub 2023 Nov 23. PMID: 38000629 DOI: 10.1016/j.jtcvs.2023.11.023. Online ahead of print.
Kaseda K, Asakura K, Shintani Y, Okami J, Toyooka S, Sato Y, Watanabe SI, Chida M, Suzuki H, Miyaoka E, Yoshino I, Date H; Japanese Joint Committee of Lung Cancer Registry. Surgically resected sarcomatoid carcinoma of the lung: a nationwide retrospective study in 2010. BMC Cancer. 2024 Aug 2;24(1):938. PMID: 39095716. PMCID: PMC11295483. DOI: 10.1186/s12885-024-12728-2.
Nakagawa K, Yotsukura M, Mimae T, Hattori A, Miyoshi T, Isaka M, Endo M, Tsutani Y, Isaka T, Maniwa T, Nakajima R, Yoshioka H, Takei H, Aokage K, Watanabe SI.　 The Lung Cancer Surgical Study Group of the Japan Clinical Oncology Group: outstanding contribution and entering a new phase. Jpn J Clin Oncol. 2024 Aug 19:hyae100. PMID: 39158320 DOI: 10.1093/jjco/hyae100. Online ahead of print.
Tane K, Shiono S, Wakabayashi M, Kataoka T, Mitome N, Fukuda H, Aokage K, Watanabe SI; In behalf of the Lung Cancer Surgical Study Group/Japan Clinical Oncology Group. A randomized phase III trial of postoperative surveillance for pathological stage II and IIIA non-small cell lung cancer (JCOG2012, PHOENIX). Clinical Trial Jpn J Clin Oncol. 2024 Aug 14;54(8):926-929. PMID: 38693750 DOI: 10.1093/jjco/hyae056.
Kaseda K, Asakura K, Shintani Y, Okami J, Toyooka S, Sato Y, Watanabe SI, Chida M, Suzuki H, Miyaoka E, Yoshino I, Date H; Japanese Joint Committee of Lung Cancer Registry. Surgically resected sarcomatoid carcinoma of the lung: a nationwide retrospective study in 2010. BMC Cancer. 2024 Aug 2;24(1):938.　　PMID: 39095716 PMCID: PMC11295483 DOI: 10.1186/s12885-024-12728-2.
Mochizuki A, Shiraishi K, Honda T, Higashiyama RI, Sunami K, Matsuda M, Shimada Y, Miyazaki Y, Yoshida Y, Watanabe SI, Yatabe Y, Hamamoto R, Kohno T. Passive Smoking-Induced Mutagenesis as a Promoter of Lung Carcinogenesis. J Thorac Oncol. 2024 Jul;19(7):984-994. PMID: 38382595. DOI: 10.1016/j.jtho.2024.02.006. Epub 2024 Feb 19.
Rami-Porta R, Nishimura KK, Giroux DJ, Detterbeck F, Cardillo G, Edwards JG, Fong KM, Giuliani M, Huang J, Kernstine KH Sr, Marom EM, Nicholson AG, Van Schil PE, Travis WD, Tsao MS, Watanabe SI, Rusch VW, Asamura H; Members of the IASLC Staging and Prognostic Factors Committee and of the Advisory Boards, and Participating Institutions. The International Association for the Study of Lung Cancer Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groups in the Forthcoming (Ninth) Edition of the TNM Classification for Lung Cancer. J Thorac Oncol. 2024 Jul;19(7):1007-1027. doi: 10.1016/j.jtho.2024.02.011. Epub 2024 Mar 4.
Travis WD, Eisele M, Nishimura KK, Aly RG, Bertoglio P, Chou TY, Detterbeck FC, Donnington J, Fang W, Joubert P, Kernstine K, Kim YT, Lievens Y, Liu H, Lyons G, Mino-Kenudson M, Nicholson AG, Papotti M, Rami-Porta R, Rusch V, Sakai S, Ugalde P, Van Schil P, Yang CJ, Cilento VJ, Yotsukura M, Asamura H; Members of the International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee, Members of the Advisory Boards, and Participating Institutions of the Lung Cancer Domain. The International Association for the Study of Lung Cancer (IASLC) Staging Project for Lung Cancer: Recommendation to Introduce Spread Through Air Spaces as a Histologic Descriptor in the Ninth Edition of the TNM Classification of Lung Cancer. Analysis of 4061 Pathologic Stage I NSCLC. J Thorac Oncol. 2024 Jul;19(7):1028-1051. PMID: 38508515 DOI: 10.1016/j.jtho.2024.03.015. Epub 2024 Mar 18.
Kaneko S, Takasawa K, Asada K, Shiraishi K, Ikawa N, Machino H, Shinkai N, Matsuda M, Masuda M, Adachi S, Takahashi S, Kobayashi K, Kouno N, Bolatkan A, Komatsu M, Yamada M, Miyake M, Watanabe H, Tateishi A, Mizuno T, Okubo Y, Mukai M, Yoshida T, Yoshida Y, Horinouchi H, Watanabe SI, Ohe Y, Yatabe Y, Saloura V, Kohno T, Hamamoto R. Mechanism of ERBB2 gene overexpression by the formation of super-enhancer with genomic structural abnormalities in lung adenocarcinoma without clinically actionable genetic alterations. Mol Cancer. Mol Cancer. 2024 Jun 11;23(1):126. PMID: 38862995 PMCID: PMC11165761 DOI: 10.1186/s12943-024-02035-6.
Fukuda H, Arai K, Mizuno H, Nishito Y, Motoi N, Arai Y, Hiraoka N, Shibata T, Sonobe Y, Kayukawa Y, Hashimoto E, Takahashi M, Fujii E, Maruyama T, Kuwabara K, Nishizawa T, Mizoguchi Y, Yoshida Y, Watanabe SI, Yamashita M, Kitano S, Sakamoto H, Nagata Y, Mitsumori R, Ozaki K, Niida S, Kanai Y, Hirayama A, Soga T, Tsukada K, Yabuki N, Shimada M, Kitazawa T, Natori O, Sawada N, Kato A, Yoshida T, Yasuda K, Ochiai A, Tsunoda H, Aoki K. Molecular subtypes of lung adenocarcinoma present distinct immune tumor microenvironments. Cancer Sci. 2024 Jun;115(6):1763-1777. PMID: 38527308 PMCID: PMC11145114. DOI: 10.1111/cas.16154. Epub 2024 Mar 25.
Van Schil PE, Asamura H, Nishimura KK, Rami-Porta R, Kim YT, Bertoglio P, Cangir AK, Donington J, Fang W, Giroux DJ, Lievens Y, Liu H, Lyons G, Sakai S, Travis WD, Ugalde P, Jeffrey Yang CF, Yotsukura M, Detterbeck F; Members of the International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee, Advisory Boards and Participating Institutions. The International Association for the Study of Lung Cancer Lung Cancer Staging Project: Proposals for the Revisions of the T-Descriptors in the Forthcoming Ninth Edition of the TNM Classification for Lung Cancer. J Thorac Oncol. 2024 May;19(5):749-765.　 PMID: 38070600 PMCID: PMC11081813 (available on 2025-05-01) DOI: 10.1016/j.jtho.2023.12.006. Epub 2023 Dec 7.
Yoshizumi Y, Yokota Y, Ishikawa T, Nagae K, Watanabe SI, Nakamura Y, Kouno K. Quantitative identification of causes of instrumental acoustic signal distortion in Global Navigation Satellite System-Acoustics Combination observations. J Acoust Soc Am. 2024 Apr 1;155(4):2786-2793. PMID: 38662606 DOI: 10.1121/10.0025770.
Tane S, Okami J, Maniwa Y, Shintani Y, Ito H, Ohtsuka T, Toyooka S, Mori T, Watanabe SI, Chida M, Endo S, Nakanishi R, Kadokura M, Suzuki H, Miyaoka E, Yoshino I, Date H; Japanese Joint Committee of Lung Cancer Registry. Clinical outcomes of left upper segmentectomy vs. lobectomy for early non-small-cell lung cancer: a nationwide database study in Japan. Surg Today. 2024 Apr 18. PMID: 38635057 DOI: 10.1007/s00595-024-02844-8. Online ahead of print.
Detterbeck FC, Ostrowski M, Hoffmann H, Rami-Porta R, Osarogiagbon RU, Donnington J, Infante M, Marino M, Marom EM, Nakajima J, Nicholson AG, van Schil P, Travis WD, Tsao MS, Edwards JG, Asamura H; Members of the Staging and Prognostic Factors Committee and Advisory Boards.. The IASLC Lung Cancer Staging Project: Proposals for Revision of the Classification of Residual Tumor after Resection for the Forthcoming (9th) Edition of the TNM Classification of Lung Cancer. J Thorac Oncol. 2024 Apr 1:S1556-0864(24)00129-1. PMID:38569931, DOI: 10.1016/j.jtho.2024.03.021. Online ahead of print.
Sakashita M, Motoi N, Yamamoto G, Gambe E, Suzuki M, Yoshida Y, Watanabe SI, Takazawa Y, Aoki K, Ochiai A, Sakashita S. An algorithm-based technique for counting mitochondria in cells using immunohistochemical staining of formalin-fixed and paraffin-embedded sections. J Cancer Res Clin Oncol. 2024 Apr 3;150(4):172. PMID: 38565653 DOI: 10.1007/s00432-024-05653-1.

雑誌論文（和文）

1．和文論文

竹村千尋,渡辺俊一．定期的区域切除における基本手技,II. 呼吸器外科領域,【特集】胸部外科手術の基本手技とコツ 2024,胸部外科,77（10）,2024年9月号増刊．

2．著書・総説・Textbook

渡辺俊一（監修）,大江裕一郎（監修）,大熊加恵（監修）．尾和みゆき（発行人）．国立がん研究センターの肺がんの本（改訂新版）．小学館． pp1-169,2025年3月．発行所：東京．